The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Estimating the Effect of Palliative Care Interventions and Advance Care Planning on ICU Utilization: A Systematic Review*
Open accessAbstract
OBJECTIVE: We conducted a systematic review to answer three questions: 1) Do advance care planning and palliative care interventions lead to a reduction in ICU admissions for adult patients with life-limiting illnesses? 2) Do these interventions reduce ICU length of stay? and 3) Is it possible to provide estimates of the magnitude of these effects? DATA SOURCES: We searched MEDLINE, EMBASE, Cochrane Controlled Clinical Trials, and Cumulative Index to Nursing and Allied Health Literature databases from 1995 through March 2014. STUDY SELECTION: We included studies that reported controlled trials (randomized and nonrandomized) assessing the impact of advance care planning and both primary and specialty palliative care interventions on ICU admissions and ICU length of stay for critically ill adult patients. DATA EXTRACTION: Nine randomized controlled trials and 13 nonrandomized controlled trials were selected from 216 references. DATA SYNTHESIS: Nineteen of these studies were used to provide estimates of the magnitude of effect of palliative care interventions and advance care planning on ICU admission and length of stay. Three studies reporting on ICU admissions suggest that advance care planning interventions reduce the relative risk of ICU admission for patients at high risk of death by 37% (SD, 23%). For trials evaluating palliative care interventions in the ICU setting, we found a 26% (SD, 23%) relative risk reduction in length of stay with these interventions. CONCLUSIONS: Despite wide variation in study type and quality, patients who received advance care planning or palliative care interventions consistently showed a pattern toward decreased ICU admissions and reduced ICU length of stay. Although SDs are wide and study quality varied, the magnitude of the effect is possible to estimate and provides a basis for modeling impact on healthcare costs.
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Cites
Consort 2010 statement: extension to cluster randomised trials
Campbell, M. K., Piaggio, G., Elbourne, D. R., Altman, D. G., & for the CONSORT Group (2012) · BMJ · doi:10.1136/bmj.e5661 · Cited by 3,510
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CONSORT statement: extension to cluster randomised trials
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Detering, K. M., Hancock, A. D., Reade, M. C., & Silvester, W. (2010) · BMJ · doi:10.1136/bmj.c1345 · Cited by 2,332 · cited 3×
“In the first trial, Detering et al (24) assessed the impact of advance care planning on end-of-life care.”
BackgroundMethodInfluentialBoutron, I., Moher, D., Altman, D. G., Schulz, K. F., Ravaud, P., & for the CONSORT Group* (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-4-200802190-00008 · Cited by 2,292
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A communication strategy and brochure for relatives of patients dying in the ICU.
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“…not designed to study the effect of the intervention on resource utilization because patients were recruited if expected to die within a few days (18); 3) one study with a very small sample size (n = 10/2009 eligible) (19); and 4) one study confounded by indication bias that did not report…”
BackgroundSelf-citationTeno, J. M., Gozalo, P. L., Bynum, J. P. W., Leland, N. E., Miller, S. C., Morden, N. E., Scupp, T., Goodman, D. C., & Mor, V. (2013) · JAMA · doi:10.1001/jama.2012.207624 · Cited by 966
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Cited by
Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4683-6 · Cited by 6,621
Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002255 · Cited by 3,652
Guidelines for Family-Centered Care in the Neonatal, Pediatric, and Adult ICU
Davidson, J. E., Aslakson, R. A., Long, A. C., Puntillo, K. A., Kross, E. K., Hart, J., Cox, C. E., Wunsch, H., Wickline, M. A., Nunnally, M. E., et al. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002169 · Cited by 1,540
Self-citationMcMahan, R. D., Tellez, I., & Sudore, R. L. (2021) · Journal of the American Geriatrics Society · doi:10.1111/jgs.16801 · Cited by 506
Early palliative care consultation in the medical ICU: A cluster randomized crossover trial.
Ma, J., Chi, S., Buettner, B., Pollard, K., Muir, M., Kolekar, C., Al-Hammadi, N., Chen, L., Kollef, M., & Dans, M. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000004016 · Cited by 166
Metadata
- Authors
- Khandelwal, N., Kross, E. K., Engelberg, R. A., Coe, N. B., Long, A. C., & Curtis, J. R.
- Venue
- Critical Care Medicine
- Published
- 2015-05
- Volume
- 43
- Issue
- 5
- Pages
- 1102-1111
- ISSN
- 0090-3493 (ISSN-L)
- OpenAlex
- W2011510408
- Cited by
- 317
- References
- 40
- FWCI
- 31.38
- Type
- journal article
- Language
- en
- Open access
- green
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- Khandelwal, N., Kross, E. K., Engelberg, R. A., Coe, N. B., Long, A. C., & Curtis, J. R. (2015). Estimating the Effect of Palliative Care Interventions and Advance Care Planning on ICU Utilization: A Systematic Review*. Critical Care Medicine. https://doi.org/10.1097/ccm.0000000000000852
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