Cited by 43Skin Protection and AgingDermatologic Treatments and Researchmelanin and skin pigmentation

Daily Use of a Facial Broad Spectrum Sunscreen Over One-Year Significantly Improves Clinical Evaluation of Photoaging

Randhawa, Manpreet, Wang, Steven, Leyden, James J., Cula, Gabriela O., Pagnoni, Alessandra, Southall, Michael D.·2016·Dermatologic Surgery

Abstract

BACKGROUND: Sunscreens are known to protect from sun damage; however, their effects on the reversal of photodamage have been minimally investigated. OBJECTIVE: The aim of the prospective study was to evaluate the efficacy of a facial sun protection factor (SPF) 30 formulation for the improvement of photodamage during a 1-year use. METHODS: Thirty-two subjects applied a broad spectrum photostable sunscreen (SPF 30) for 52 weeks to the entire face. Assessments were conducted through dermatologist evaluations and subjects' self-assessment at baseline and then at Weeks 12, 24, 36, and 52. RESULTS: Clinical evaluations showed that all photoaging parameters improved significantly from baseline as early as Week 12 and the amelioration continued until Week 52. Skin texture, clarity, and mottled and discrete pigmentation were the most improved parameters by the end of the study (40% to 52% improvement from baseline), with 100% of subjects showing improvement in skin clarity and texture. CONCLUSION: The daily use of a facial broad-spectrum photostable sunscreen may visibly reverse the signs of existing photodamage, in addition to preventing additional sun damage.

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Crossref · 10.1097/dss.0000000000000879

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4 of 4 references verified0 citation errors · 0 not checkable

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  • Evidence suggests that sunscreens may play a role in the reversal of extrinsic aging.

    “Not only have sunscreens been shown to prevent photoaging but evidence also suggests that they may play a role in the reversal of extrinsic aging.”

    From Sunscreens and Photoaging: A Review of Current Literature (2021) · cites this paper as [40]

  • In a prospective study, 32 subjects applying daily broad-spectrum photostable sunscreen (SPF 30) for 52 weeks showed significant improvements in skin texture, clarity, and mottled and discrete pigmentation, with 100% of subjects showing improvement in skin clarity and texture.

    “In a prospective study, 32 subjects were asked to apply daily broad-spectrum photostable sunscreen (SPF 30) for 52 weeks. At the end of the study, significant improvements in skin texture, clarity, and mottled and discrete pigmentation were observed, with 100% of subjects showing improvement in skin clarity and texture [40].”

    From Sunscreens and Photoaging: A Review of Current Literature (2021) · cites this paper as [40]

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Authors
Randhawa, M., Wang, S., Leyden, J. J., Cula, G. O., Pagnoni, A., & Southall, M. D.
Affiliations
  • Johnson & Johnson (United States) (US)
  • Memorial Sloan Kettering Cancer Center (US)
  • KGL Skin Study Center (US)
  • Pagnoni Consulting LLC
Corresponding author
  • Randhawa, Manpreet
  • Cula, Gabriela O.
  • Southall, Michael D.
Venue
Dermatologic Surgery
Published
2016-12
Volume
42
Issue
12
Pages
1354-1361
ISSN
  • 1076-0512 (ISSN-L)
  • 1524-4725
OpenAlex
W2529457061
Cited by
43
References
4
Citations by year
2026: 7 · 2025: 5 · 2024: 2 · 2023: 9 · 2022: 6 · 2021: 8 · 2020: 3 · 2019: 2 · 2018: 1
FWCI
1.20
Type
journal article
Language
en
Open access
closed
Locations
  • Dermatologic Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
Keywords
broad-spectrum sunscreen, photoprotection, photoaging, skin texture, skin pigmentation
MeSH terms
Administration, Cutaneous, Adult, Female, Humans, Middle Aged, Prospective Studies, Sunlight, Sunscreening Agents, Skin Aging

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