Double-Edged Action of SOD Mimetic in Diabetic Nephropathy

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Reactive Oxygen Species-Regulated Signaling Pathways in Diabetic Nephropathy

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Translocation of Glomerular p47phox and p67phox by Protein Kinase C-β Activation Is Required for Oxidative Stress in Diabetic Nephropathy

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Oxidative Stress in Dahl Salt-Sensitive Hypertension

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Oxidant stress in hyperlipidemia-induced renal damage

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The expression of the NADPH oxidase subunit p22phox is regulated by a redox-sensitive pathway in endothelial cells

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Selenium-deficient diet induces renal oxidative stress and injury via TGF-β1 in normal and diabetic rats

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The SOD mimetic tempol restores vasodilation in afferent arterioles of experimental diabetes

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Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury

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Leukocyte-Derived Myeloperoxidase Amplifies High-Glucose—Induced Endothelial Dysfunction Through Interaction With High-Glucose—Stimulated, Vascular Non—Leukocyte-Derived Reactive Oxygen Species

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Tempol Lowers Blood Pressure and Sympathetic Nerve Activity But Not Vascular O 2 − in DOCA-Salt Rats

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Eplerenone Shows Renoprotective Effect by Reducing LOX-1–Mediated Adhesion Molecule, PKCε-MAPK-p90RSK, and Rho-Kinase Pathway

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The SOD Mimetic Tempol Ameliorates Glomerular Injury and Reduces Mitogen-Activated Protein Kinase Activity in Dahl Salt-Sensitive Rats

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Endogenous Adrenomedullin Protects Against Vascular Response to Injury in Mice

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Immunohistochemical Detection of Hypochlorite-Modified Proteins in Glomeruli of Human Membranous Glomerulonephritis

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Neuroprotection by tempol in a model of iron-induced oxidative stress in acute ischemic stroke

Mehta, S. H., Webb, R. C., Ergul, A., Tawak, A., & Dorrance, A. M. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00446.2002 · Cited by 59 · see citing works

Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet

Onozato, M. L., Tojo, A., Goto, A., & Fujita, T. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00470.x · Cited by 56 · see citing works

Tempol Attenuates the Development of Hypertensive Renal Injury in Dahl Salt-Sensitive Rats

HISAKI, R., FUJITA, H., Saito, F., & Kushiro, T. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2004.11.045 · Cited by 55 · see citing works

Tempol, an intracelullar free radical scavenger, reduces liver injury in hepatic ischemia-reperfusion in the rat

Sepodes, B. M. N., Maio, R., Pinto, R. M. A., Marques, C., Mendes-do-Vale, J., McDonald, M. C., Thiemermann, C., & Mota‐Filipe, H. (2004) · Transplantation Proceedings · doi:10.1016/j.transproceed.2004.03.050 · Cited by 45 · see citing works

Tempol, a Novel Stable Nitroxide, Reduces Brain Damage and Free Radical Production, after Acute Subdural Hematoma in the Rat

Kwon, T.-H., Chao, D. L., Malloy, K., Sun, D., Alessandri, B., & Bullock, M. R. (2003) · Journal of Neurotrauma · doi:10.1089/089771503765172291 · Cited by 41 · see citing works

Cardiac and renal antioxidant enzymes and effects of tempol in hyperthyroid rats

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Distribution of postsynaptic density proteins in rat kidney: Relationship to neuronal nitric oxide synthase

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TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney

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Nitric oxide generated by nNOS in the macula densa regulates the afferent arteriolar diameter in rat kidney

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Role of NADPH Oxidase in Hypertension and Diabetic Nephropathy

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Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes

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Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities

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Relationship between Oxidative Stress and Inflammatory Cytokines in Diabetic Nephropathy

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Antioxidants and human diseases

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Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease

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Effects of tempol and redox-cycling nitroxides in models of oxidative stress

Wilcox, C. S. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.01.003 · Cited by 466 · see citing works

Chemistry and Antihypertensive Effects of Tempol and Other Nitroxides

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Mechanistic insight of diabetic nephropathy and its pharmacotherapeutic targets: An update

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Suppressing renal NADPH oxidase to treat diabetic nephropathy

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Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells

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Antioxidant SOD Mimetic Prevents NADPH Oxidase-Induced Oxidative Stress and Renal Damage in the Early Stage of Experimental Diabetes and Hypertension

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Therapeutic strategies of diabetic nephropathy: recent progress and future perspectives

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Stimulation of Reactive Oxygen Species and Collagen Synthesis by Angiotensin II in Cardiac Fibroblasts

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NADH/NAD+ Redox Imbalance and Diabetic Kidney Disease

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Tipping the redox balance of oxidative stress in fibrogenic pathways in chronic kidney disease

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Green tea (Camellia sinensis) Attenuates Nephropathy by Downregulating Nox4 NADPH Oxidase in Diabetic Spontaneously Hypertensive Rats

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Extracellular superoxide dismutase ameliorates streptozotocin-induced rat diabetic nephropathy via inhibiting the ROS/ERK1/2 signaling

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Superoxide Modulates Myogenic Contractions of Mouse Afferent Arterioles

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Renal and metabolic effects of tempol in obese ZSF1 rats—distinct role for superoxide and hydrogen peroxide in diabetic renal injury

Rafikova, O., Salah, E., & Tofovic, S. P. (2008) · Metabolism · doi:10.1016/j.metabol.2008.05.014 · Cited by 41 · see citing works

The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy

Blasio, M. J. D., Ramalingam, A. R., Cao, A. H., Prakoso, D., Ye, J., Pickering, R. J., Watson, A. M. D., de Haan, J. B., Kaye, D. M., & Ritchie, R. H. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.04.026 · Cited by 41 · see citing works

Circulating Expression Level of LncRNA Malat1 in Diabetic Kidney Disease Patients and Its Clinical Significance

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Inhibition of Superoxide Dismutase Induces Collagen Production in Cardiac Fibroblasts

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Effect of Chronic Antioxidant Therapy with Superoxide Dismutase-Mimetic Drug, Tempol, on Progression of Renal Disease in Rats with Renal Mass Reduction

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Effects of Single and Combined Losartan and Tempol Treatments on Oxidative Stress, Kidney Structure and Function in Spontaneously Hypertensive Rats with Early Course of Proteinuric Nephropathy

Karanović, D., Grujić-Milanović, J. D., Miloradović, Z., Ivanov, M., Jovović, D., Vajić, U.-J., Životić, M., Markovic‐Lipkovski, J., & Mihailovic‐Stanojevic, N. (2016) · PLoS ONE · doi:10.1371/journal.pone.0161706 · Cited by 31 · see citing works

Tempol Prevents Altered K + Channel Regulation of Afferent Arteriolar Tone in Diabetic Rat Kidney

Brindeiro, C. M. T., Lane, P. H., & Carmines, P. K. (2012) · Hypertension · doi:10.1161/hypertensionaha.111.184218 · Cited by 29 · see citing works

Inhibition of renal gluconeogenesis contributes to hypoglycaemic action of NADPH oxidase inhibitor, apocynin

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Free radical scavenging decreases endothelin‐1 excretion and glomerular albumin permeability during type 1 diabetes

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Serum and urinary SOD3 in patients with type 2 diabetes: comparison with early chronic kidney disease patients and association with development of diabetic nephropathy

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Discovery of 1-(4-((3-(4-methylpiperazin-1-yl)propyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one, an orally active multi-target agent for the treatment of diabetic nephropathy

Chen, J., Peng, Z., Lu, M., Xiong, X., Chen, Z., Li, Q., Cheng, Z., Jiang, D., Tao, L., & Hu, G. (2017) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2017.07.001 · Cited by 8 · see citing works

Modulation of Reactive Oxygen Species and Collagen Synthesis by Angiotensin II in Cardiac Fibroblasts

Lijnen, P. J. (2011) · The Open Hypertension Journal · doi:10.2174/1876526201104010001 · Cited by 7 · see citing works

Mitochondrial Oxidative Stress in Diabetes

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Novel Mn-SOD Mimetics Offer Superior Protection Against Oxidative Damages in Hek293 Kidney Cells

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O cha verde (Camellia sinensis) atenua a nefropatia atraves da redução da expressão da subunidade NOX-4 da ND(P)H oxidase no diabetes mellitus experimental

Ribaldo, P. D. B. (2008) · doi:10.47749/t/unicamp.2008.434390

Tempol e renoprotetor na nefropatia diabetica experimental

Peixoto, E. B. M. I. (2010) · doi:10.47749/t/unicamp.2010.476391

Studies on Angiotensin Converting Enzyme 2, Angiotensin-(1-7), and p47phox-Dependent NADPH Oxidase and their Roles in Diabetic Nephropathy

Liu, C. (2012) · TSpace (University of Toronto)

Antioxidative Effects of Tempol on Mitochondrial Dysfunction in Diabetic Nephropathy.

Ranjbar, A., Kheiripour, N., Ghasemi, H., Rabiei, M. A. S., Dadras, F., & Khoshjou, F. (2018) · Iranian Journal of Kidney Diseases · Cited by 16 · see citing works

The superoxide dismutase mimetic tempol blunts diabetes-induced upregulation of NADPH oxidase and endoplasmic reticulum stress in a rat model of diabetic nephropathy

Blasio, M. J. D., Ramalingam, A. R., Cao, A. H., Prakoso, D., Ye, J., Pickering, R. J., Watson, A. M. D., de Haan, J. B., Kaye, D. M., & Ritchie, R. H. (2017) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2017.04.026 · Cited by 41 · see citing works

Antioxidant SOD Mimetic Prevents NADPH Oxidase-Induced Oxidative Stress and Renal Damage in the Early Stage of Experimental Diabetes and Hypertension

Peixoto, E. B. M. I., Pessôa, B. S., Biswas, S. K., & de Faria, J. B. L. (2008) · American Journal of Nephrology · doi:10.1159/000163767 · Cited by 86 · see citing works

Tempol effects on diabetic nephropathy in male rats

Ranjbar, A., Ghasemi, H., Hatami, M., Dadras, F., Shayesteh, T. H., & Khoshjou, F. (2016) · Journal of Renal Injury Prevention · doi:10.15171/jrip.2016.16 · Cited by 18 · see citing works

Renal and metabolic effects of tempol in obese ZSF1 rats—distinct role for superoxide and hydrogen peroxide in diabetic renal injury

Rafikova, O., Salah, E., & Tofovic, S. P. (2008) · Metabolism · doi:10.1016/j.metabol.2008.05.014 · Cited by 41 · see citing works