The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Fibrosis and Cardiac Arrhythmias
Abstract
In this review article about fibrosis and arrhythmias, we show that the amount of collagen, a normal element of the heart muscle, increases with age and in heart disease. The relation between fibrosis and electrophysiological parameters such as conduction, fractionation of electrograms, abnormal impulse initiation as well as arrhythmogenicity is discussed. Next to the amount of fibrosis, we offer data suggesting that collagen texture too plays a role in conduction slowing and arrhythmia vulnerability. Data are shown revealing that fibrosis can also be induced by reduced sodium channel and connexin43 expression. Finally contrast-enhanced magnetic resonance to detect fibrosis and ventricular tachycardia vulnerability in a noninvasive way as well as a reduction of fibrosis and arrhythmogenicity by inhibition of the renin-angiotensin-aldosterone system is discussed.
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Cites
The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure
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Kim, R. J., Fieno, D. S., Parrish, T. B., Harris, K., Chen, E.-L., Simonetti, O., Bundy, J., Finn, J. P., Klocke, F. J., & Judd, R. M. (1999) · Circulation · doi:10.1161/01.cir.100.19.1992 · Cited by 2,581
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Molecular Mechanisms of Myocardial Remodeling
SWYNGHEDAUW, B. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.1.215 · Cited by 1,460
Promotion of Atrial Fibrillation by Heart Failure in Dogs: Atrial Remodeling of a Different Sort
Li, D., Fareh, S., Leung, T. K., & Nattel, S. (1999) · Circulation · doi:10.1161/01.cir.100.1.87 · Cited by 1,341
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Slow conduction in the infarcted human heart. 'Zigzag' course of activation.
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Self-citationSchmidt, A., Azevedo, C. F., Cheng, A., Gupta, S. N., Bluemke, D. A., Foo, T. K., Gerstenblith, G., Weiss, R. G., Marbán, E., Tomaselli, G. F., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.653568 · Cited by 823
Cited by
Cardiac fibrosis – A short review of causes and therapeutic strategies
Hinderer, S., & Schenke-Layland, K. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.05.011 · Cited by 490
Zorzi, A., Perazzolo Marra, M., Rigato, I., De Lazzari, M., Susana, A., Niero, A., Pilichou, K., Migliore, F., Rizzo, S., Giorgi, B., et al. (2016) · Circulation: Arrhythmia and Electrophysiology · doi:10.1161/circep.116.004229 · Cited by 326
Mosaic deficiency in mitochondrial oxidative metabolism promotes cardiac arrhythmia during aging
Baris, O. R., Ederer, S., Neuhaus, J. F. G., von Kleist-Retzow, J.-C., Wunderlich, C. M., Pal, M., Wunderlich, F. T., Peeva, V., Zsurka, G., Kunz, W. S., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.04.005 · Cited by 87
Metadata
- Authors
- de Jong, S., van Veen, T. A. B., van Rijen, H. V. M., & de Bakker, J. M. T.
- Venue
- Journal of Cardiovascular Pharmacology
- Published
- 2011-06
- Volume
- 57
- Issue
- 6
- Pages
- 630-638
- ISSN
- 0160-2446 (ISSN-L)
- OpenAlex
- W1911769041
- Cited by
- 360
- References
- 64
- FWCI
- 7.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Fibrosis and Cardiac Arrhythmias. https://app.cochat.ai/papers/10.1097/fjc.0b013e318207a35f
- The paper
- de Jong, S., van Veen, T. A. B., van Rijen, H. V. M., & de Bakker, J. M. T. (2011). Fibrosis and Cardiac Arrhythmias. Journal of Cardiovascular Pharmacology. https://doi.org/10.1097/fjc.0b013e318207a35f
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
