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Cited by 194Menopause: Health Impacts and TreatmentsSexual function and dysfunction studiesEstrogen and related hormone effects

Duration of vasomotor symptoms in middle-aged women: a longitudinal study

Col, Nananda F., Guthrie, Janet R., Politi, Mary, Dennerstein, Lorraine·2009·Menopause
DOI 10.1097/gme.0b013e31818d414e
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Abstract

OBJECTIVE: Vasomotor symptoms adversely affect the quality of life and functional status of most women during the menopausal transition, but little is known about how long these symptoms last. The most effective treatment, hormone therapy (HT), carries risks and benefits that depend on the timing and duration of use. In this study we sought to estimate the duration of vasomotor symptoms in a longitudinal study. METHODS: We reanalyzed primary data from 438 women in the longitudinal cohort of the population-based Melbourne Women's Midlife Health Project. Two hundred and five women who had completed 13 years of follow-up were included in the analyses. The onset and cessation of vasomotor symptoms were reported, stratifying analyses according to ever use of HT. Symptom duration was calculated as the time between the first and last bothersome hot flush reported. RESULTS: The mean (SD) duration of bothersome menopausal symptoms for women who completed 13 years of follow-up and who never used HT was estimated to be 5.2 (3.8) years (median, 4 years). If women who used HT were included, the mean (SD) duration was 5.5 (4.0) years (median, 4 years). The estimated duration of symptoms varied according to the duration of longitudinal follow-up, with a mean estimate of 3.4 years (median, 3 years) when only 8 years of follow-up data were analyzed. The only factor associated with duration of hot flushes was regular exercise-more exercise was associated with shorter symptom duration. CONCLUSIONS: The average duration of vasomotor symptoms in this sample is more than 5 years, substantially longer than had been previously reported.

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Crossref · 10.1097/gme.0b013e31818d414e

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  • Hot flashes occur in 60 to 80 % of women during the menopausal transition and persist for 4 to 5 years on average.

    “it is generally believed that hot flashes occur in 60 to 80 % of women during the menopausal transition [102] and persist for 4 to 5 years on average [103,104].”

    From Non-Pharmacological Treatment of Insomnia (2012) · cites this paper as [104]

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Authors
Col, N. F., Guthrie, J. R., Politi, M., & Dennerstein, L.
Affiliations
  • Maine Medical Center (US)
  • The University of Melbourne (AU)
  • Brown University (US)
Corresponding author
Col, Nananda F.
ORCID
Venue
Menopause
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2009-05
Volume
16
Issue
3
Pages
453-457
ISSN
1072-3714 (ISSN-L)
DOI
10.1097/gme.0b013e31818d414e
OpenAlex
W2029148170
Cited by
194
References
28
Citations by year
2026: 6 · 2025: 6 · 2024: 6 · 2023: 7 · 2022: 9 · 2021: 36 · 2020: 4 · 2019: 9 · 2018: 5 · 2017: 8 · 2016: 7 · 2015: 14 · 2014: 14 · 2013: 11 · 2012: 10
FWCI
11.90
Type
journal article
Language
en
Open access
closed
Locations
  • Menopause The Journal of The North American Menopause Society (publishedVersion)
  • PubMed (publishedVersion)
Funders
Agency for Healthcare Research and Quality (2r01hs013329-04a1)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
  • Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
Keywords
vasomotor symptoms, hot flashes, menopause, symptom duration, perimenopause, hormone therapy, middle-aged women, physical activity, quality of life
MeSH terms
Cross-Sectional Studies, Female, Health Surveys, Humans, Interviews as Topic, Longitudinal Studies, Menopause, Middle Aged, Time Factors, Estrogen Replacement Therapy, Hot Flashes

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