Relation of demographic and lifestyle factors to symptoms in a multi-racial/ethnic population of women 40-55 years of age
Abstract
A community-based survey was conducted during 1995-1997 of factors related to menopausal and other symptoms in a multi-racial/ethnic sample of 16,065 women aged 40-55 years. Each of seven sites comprising the Study of Women's Health across the Nation (SWAN) surveyed one of four minority populations and a Caucasian population. The largest adjusted prevalence odds ratios for all symptoms, particularly hot flashes or night sweats (odds ratios = 2.06-4.32), were for women who were peri- or postmenopausal. Most symptoms were reported least frequently by Japanese and Chinese (odds ratios = 0.47-0.67 compared with Caucasian) women. African-American women reported vasomotor symptoms and vaginal dryness more (odds ratios = 1.17-1.63) but urine leakage and difficulty sleeping less (odds ratios = 0.64-0.72) than Caucasians. Hispanic women reported urine leakage, vaginal dryness, heart pounding, and forgetfulness more (odds ratios = 1.22-1.85). Hot flashes or night sweats, urine leakage, and stiffness or soreness were associated with a high body mass index (odds ratios = 1.15-2.18 for women with a body mass index > or =27 vs. 19-26.9 kg/m2). Most symptoms were reported most frequently among women who had difficulty paying for basics (odds ratios = 1.15-2.05), who smoked (odds ratios = 1.21-1.78), and who rated themselves less physically active than other women their age (odds ratios = 1.24-2.33). These results suggest that lifestyle, menstrual status, race/ethnicity, and socioeconomic status affect symptoms in this age group.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Hot flashes occur in 60 to 80 % of women during the menopausal transition and persist for 4 to 5 years on average.
“it is generally believed that hot flashes occur in 60 to 80 % of women during the menopausal transition [102] and persist for 4 to 5 years on average [103,104].”
From Non-Pharmacological Treatment of Insomnia (2012) · cites this paper as [102]
Cites
(1990) · Choice Reviews Online · doi:10.5860/choice.27-3338 · Cited by 35,305 · see citing works
Body Weight and Mortality among Women
Manson, J. E., Willett, W. C., Stampfer, M. J., Colditz, G. A., Hunter, D. J., Hankinson, S. E., Hennekens, C. H., & Speizer, F. E. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509143331101 · Cited by 2,005 · see citing works
Epidemiology Standardization Project (American Thoracic Society).
Bg, F. (1978) · PubMed · Cited by 1,344 · see citing works
The normal menopause transition
McKinlay, S. M., Brambilla, D. J., & Posner, J. G. (1992) · Maturitas · doi:10.1016/0378-5122(92)90003-m · Cited by 1,112 · see citing works
Michnovicz, J. J., Hershcopf, R. J., Naganuma, H., Bradlow, H. L., & Fishman, J. (1986) · New England Journal of Medicine · doi:10.1056/nejm198611203152101 · Cited by 658 · see citing works
Is there a menopausal syndrome? Menopausal status and symptoms across racial/ethnic groups
Avis, N. E., Stellato, R. K., Crawford, S. L., Bromberger, J. T., Ganz, P. A., Cain, V. S., & Kagawa‐Singer, M. (2001) · Social Science & Medicine · doi:10.1016/s0277-9536(00)00147-7 · Cited by 644 · see citing works
Characterization of reproductive hormonal dynamics in the perimenopause
Santoro, N. F., Brown, J., Adel, T., & Skurnick, J. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.4.8636357 · Cited by 550 · see citing works
Sowers, M. R., Crawford, S. L., Sternfeld, B., Morganstein, D. R., Gold, E. B., Greendale, G. A., Evans, D. A., Neer, R. M., Matthews, K. A., Sherman, S., et al. (2000) · Elsevier eBooks · doi:10.1016/b978-012453790-3/50012-3 · Cited by 539 · see citing works
Self-citationMcKinlay, S. M., & Jefferys, M. (1974) · Journal of Epidemiology & Community Health · doi:10.1136/jech.28.2.108 · Cited by 433 · see citing works
"Menopausal Symptoms" in Women of Various Ages
Neugarten, B. L., & Kraines, R. J. (1965) · Psychosomatic Medicine · doi:10.1097/00006842-196505000-00009 · Cited by 382 · see citing works
Menopausal symptoms in Australian women
Dennerstein, L., Smith, A. M. A., Morse, C. A., Burger, H., Green, A. C., Hopper, J. L., & Ryan, M. (1993) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1993.tb137821.x · Cited by 333 · see citing works
Impact of climacteric on well-being
Oldenhave, A., Jaszmann, L., Haspels, A. A., & Everaerd, W. T. A. M. (1993) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(12)90817-0 · Cited by 329 · see citing works
Avis, N. E., & McKinlay, S. M. (1991) · Maturitas · doi:10.1016/0378-5122(91)90286-y · Cited by 309 · see citing works
Relationships between psychological symptoms, somatic complaints and menopausal status
Hunter, M. S., Battersby, R., & Whitehead, M. I. (1986) · Maturitas · doi:10.1016/0378-5122(86)90029-0 · Cited by 309 · see citing works
Women's health in midlife: the influence of the menopause, social factors and health in earlier life
Kuh, D. L., Wadsworth, M. E. J., & Hardy, R. (1997) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1997.tb14352.x · Cited by 304 · see citing works
The South-East England longitudinal study of the climacteric and postmenopause
Hunter, M. S. (1992) · Maturitas · doi:10.1016/0378-5122(92)90004-n · Cited by 257 · see citing works
Menopause : biology and pathobiology
Løbo, R. A., Kelsey, J. L., & Marcus, R. (2000) · Cited by 237 · see citing works
Estrogen levels in postmenopausal women with hot flashes.
Erlik, Y., Meldrum, D. R., & Judd, H. L. (1982) · PubMed · Cited by 220 · see citing works
Matthews, K. A. (1994) · Archives of Internal Medicine · doi:10.1001/archinte.1994.00420200105011 · Cited by 195 · see citing works
Menopausal Age and Symptomatology in a General Practice
Thompson, B. E., Hart, S. A., & Durno, D. (1973) · Journal of Biosocial Science · doi:10.1017/s0021932000008956 · Cited by 195 · see citing works
Psychosocial, behavioral, and health factors related to menopause symptomatology.
Avis, N. E., Crawford, S. L., & McKinlay, S. M. (1997) · PubMed · Cited by 189 · see citing works
Risk factors for menopausal hot flashes.
Schwingl, P. J., Hulka, B. S., & Harlow, S. D. (1994) · PubMed · Cited by 157 · see citing works
Cultural construction of the menopausal syndrome: the Japanese case
Lock, M. M., Kaufert, P., & Gilbert, P. (1988) · Maturitas · doi:10.1016/0378-5122(88)90067-9 · Cited by 148 · see citing works
Contested meanings of the menopause
Lock, M. M. (1991) · The Lancet · doi:10.1016/0140-6736(91)92931-q · Cited by 145 · see citing works
The Massachusetts Women's Health Study: an epidemiologic investigation of the menopause.
Avis, N. E., & McKinlay, S. M. (1995) · PubMed · Cited by 141 · see citing works
Influences of natural menopause on health complaints: A prospective study of healthy Norwegian women
Holte, A. (1992) · Maturitas · doi:10.1016/0378-5122(92)90005-o · Cited by 139 · see citing works
Hulka, B. S., & Meirik, O. (1996) · Maturitas · doi:10.1016/0378-5122(95)00967-1 · Cited by 133 · see citing works
Does Physical Exercise Influence the Frequency of Postmenopausal Hot Flushes?
Hammar, M. L., And, G. B., & Lindgren, R. (1990) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349009013303 · Cited by 131 · see citing works
The menopausal age and climacteric complaints in Thai women in Bangkok
Chom-pootweep, S., Tankeyoon, M., Yamarat, K., et al. (1993) · Maturitas · doi:10.1016/0378-5122(93)90124-z · Cited by 124 · see citing works
Enhanced drug metabolism in cigarette smokers.
Hart, P. H., Farrell, G. C., Cooksley, W. G. E., & Powell, L. W. (1976) · BMJ · doi:10.1136/bmj.2.6028.147 · Cited by 123 · see citing works
Menopausal Age in Relation to Smoking
Lindquist, O., & Bengtsson, C. (1979) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1979.tb06006.x · Cited by 107 · see citing works
Slaven, L., & Lee, C. (1997) · Health Psychology · doi:10.1037//0278-6133.16.3.203 · Cited by 101 · see citing works
Sociodemographic Characteristics, Biological Factors, and Symptom Reporting in Midlife Women
Wilbur, J., Miller, A. M., Montgomery, A. C., et al. (1998) · Menopause The Journal of The North American Menopause Society · doi:10.1097/00042192-199805010-00008 · Cited by 96 · see citing works
3 Predictors of menopausal symptoms: psychosocial aspects
Hunter, M. S. (1993) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(05)80269-1 · Cited by 93 · see citing works
The Epidemiology of Climacteric Symptoms
Hagstad, A., & Janson, P. O. (1986) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016348609157052 · Cited by 93 · see citing works
Stadberg, E., Mattsson, L., & Milsom, I. (1997) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349709047826 · Cited by 79 · see citing works
Epidemiology of Climacteric and Post-Climacteric Complaints
Jaszmann, L. B. (2015) · Frontiers of hormone research · doi:10.1159/000394840 · Cited by 79 · see citing works
Habitual Physical Activity and Menopausal Symptoms: A Case-Control Study
Sternfeld, B., Quesenberry, C. P., & Husson, G. (1999) · Journal of Women s Health · doi:10.1089/jwh.1999.8.115 · Cited by 78 · see citing works
Physical activity and the menopause experience: A cross-sectional study
Guthrie, J. R., Smith, A. M. A., Dennerstein, L., & Morse, C. A. (1994) · Maturitas · doi:10.1016/0378-5122(94)90002-7 · Cited by 73 · see citing works
Obesity and fat distribution in relation to hot flashes in Dutch women from the DOM-project
den Tonkelaar, I., Seidell, J. C., & van Noord, P. A. H. (1996) · Maturitas · doi:10.1016/0378-5122(95)00990-6 · Cited by 69 · see citing works
A prospective study of the frequency of acute menopausal symptoms in Hong Kong Chinese women
Haines, C. J., Chung, T. K. H., & Leung, D. H. Y. (1994) · Maturitas · doi:10.1016/0378-5122(94)90123-6 · Cited by 69 · see citing works
Hormonal replacement therapy and sexuality in a population of Swedish postmenopausal women
Lindgren, R. (1993) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349309068040 · Cited by 61 · see citing works
The social and cultural context of menopause
Kaufert, P. A. (1996) · Maturitas · doi:10.1016/0378-5122(95)00972-8 · Cited by 61 · see citing works
O’Connor, V., Mar, C. D., Sheehan, M. C., Siskind, V., Fox‐Young, S., & Cragg, C. (1994) · Maturitas · doi:10.1016/0378-5122(94)90001-9 · Cited by 58 · see citing works
Cost‐Effectiveness of Hormone Replacement
Weinstein, M. C., & Tosteson, A. N. A. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb30324.x · Cited by 57 · see citing works
Adipose tissue as a source of hormones
Siiteri, P. K. (1987) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/45.1.283 · Cited by 54 · see citing works
Climacteric symptoms according to body weight in women of different socio-economic groups
Campagnoli, C., Morra, G., Belforte, P., et al. (1981) · Maturitas · doi:10.1016/0378-5122(81)90035-9 · Cited by 53 · see citing works
Wilbur, J., Dan, A. J., Hedricks, C. A., et al. (1990) · Family & Community Health · doi:10.1097/00003727-199011000-00009 · Cited by 41 · see citing works
The cross-sectional legacy: an introduction to longitudinal studies of the climacteric
Greene, J. G. (1992) · Maturitas · doi:10.1016/0378-5122(92)90002-l · Cited by 38 · see citing works
Goodman, M. J., Stewart, C. J., & Gilbert, F. J. (1977) · Journal of Gerontology · doi:10.1093/geronj/32.3.291 · Cited by 37 · see citing works
van Keep, P. A., & Lauritzen, C. (1973) · Medical Entomology and Zoology · Cited by 33 · see citing works
The relationship of energy expenditure to physical and psychologic symptoms in women at midlife.
Wilbur, J., Holm, K., & Dán, A. (1993) · PubMed · Cited by 25 · see citing works
At Third Meeting, Menopause Experts Make the Most of Insufficient Data
Skolnick, A. A. (1992) · JAMA · doi:10.1001/jama.1992.03490180015002 · Cited by 9 · see citing works
Comparison of Body Size and Age at Menopause between Mexican‐American and White American Women
Leidy, L. E. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb30368.x · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Quality of Life Among Younger Women With Breast Cancer
Avis, N. E., Crawford, S., & Manuel, J. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.05.130 · Cited by 529 · see citing works
The Role of Estrogen in Brain and Cognitive Aging
Russell, J. K., Jones, C. K., & Newhouse, P. A. (2019) · Neurotherapeutics · doi:10.1007/s13311-019-00766-9 · Cited by 257 · see citing works
Revisiting the duration of vasomotor symptoms of menopause: a meta-analysis
Politi, M. C., Schleinitz, M. D., & Col, N. F. (2008) · Journal of General Internal Medicine · doi:10.1007/s11606-008-0655-4 · Cited by 244 · see citing works
Labrie, F. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2014.06.001 · Cited by 227 · see citing works
Evaluation and management of sleep disturbance during the menopause transition
Joffe, H., Massler, A., & Sharkey, K. (2010) · Seminars in Reproductive Medicine · doi:10.1055/s-0030-1262900 · Cited by 195 · see citing works
Duration of vasomotor symptoms in middle-aged women: a longitudinal study
Col, N. F., Guthrie, J. R., Politi, M., & Dennerstein, L. (2009) · Menopause · doi:10.1097/gme.0b013e31818d414e · Cited by 194 · see citing works
Mindfulness training for coping with hot flashes: results of a randomized trial
Carmody, J. F., Crawford, S., Salmoirago-Blotcher, E., Leung, K., Churchill, L., & Olendzki, N. (2011) · Menopause · doi:10.1097/gme.0b013e318204a05c · Cited by 188 · see citing works
Menopausal hot flushes and night sweats: where are we now?
Archer, D. F., Sturdee, D. W., Baber, R., de Villiers, T. J., Pines, A., Freedman, R. R., Gompel, A., Hickey, M., Hunter, M. S., Lobo, R. A., et al. (2011) · Climacteric · doi:10.3109/13697137.2011.608596 · Cited by 185 · see citing works
Non-Pharmacological Treatment of Insomnia
Siebern, A. T., Suh, S., & Nowakowski, S. (2012) · Neurotherapeutics · doi:10.1007/s13311-012-0142-9 · Cited by 88 · see citing works
Kronenberg, F. (2010) · The Journal of Nutrition · doi:10.3945/jn.109.120840 · Cited by 73 · see citing works
Symptoms of menopause: hot flushes
SANTORO, N. (2008) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0b013e31818093f6 · Cited by 56 · see citing works
Chilcot, J., Norton, S., & Hunter, M. S. (2014) · Maturitas · doi:10.1016/j.maturitas.2014.01.007 · Cited by 45 · see citing works
Anderson, D. J., Seib, C., McCarthy, A. L., Yates, P., Porter-Steele, J., McGuire, A., & Young, L. (2015) · Menopause · doi:10.1097/gme.0000000000000421 · Cited by 45 · see citing works
Sievert, L. L., Murphy, L., Morrison, L. A., Reza, A. M., & Brown, D. E. (2013) · Maturitas · doi:10.1016/j.maturitas.2013.08.007 · Cited by 36 · see citing works
- Authors
- Gold, E. B.
- Affiliations
- University of California, Davis (US)
- Corresponding author
- Gold, E. B.
- ORCID
- Gold, E. B.
- Venue
- American Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-09-01
- Volume
- 152
- Issue
- 5
- Pages
- 463-473
- ISSN
- 0002-9262 (ISSN-L)
- OpenAlex
- W2124167012
- Cited by
- 861
- References
- 54
- Citations by year
- 2026: 25 · 2025: 25 · 2024: 25 · 2023: 16 · 2022: 29 · 2021: 35 · 2020: 30 · 2019: 20 · 2018: 35 · 2017: 24 · 2016: 40 · 2015: 32 · 2014: 38 · 2013: 47 · 2012: 36
- FWCI
- 11.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (U01-AG12505, U01AG012505, U01 AG12531, U01AG012531)
- National Institute of Nursing Research (U01-NR-04061, U01NR004061)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
- Keywords
- menopausal symptoms, hot flashes, night sweats, vasomotor symptoms, vaginal dryness, urinary incontinence, sleep disorders, body mass index, smoking, physical activity, socioeconomic status, race and ethnicity, African American women, Hispanic women, Japanese women, Chinese women, middle-aged women, Study of Women's Health Across the Nation
- MeSH terms
- Adult, Demography, Ethnicity, Female, Health Surveys, Humans, Life Style, Menopause, Middle Aged, Physical Fitness, Risk Factors, Smoking, Women's Health, Hot Flashes
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review