Heart failure and sleep-disordered breathing
Abstract
PURPOSE OF REVIEW: Sleep-disordered breathing, which includes both obstructive and central sleep apnoea (OSA and CSA, respectively), is highly prevalent in patients with heart failure. In this review, we outline our current understanding of the bidirectional relationship between these disorders and heart failure. We also explore the role of recent advances in therapeutics. RECENT FINDINGS: Although early studies suggest promise of adaptive servoventilation in treating sleep-disordered breathing, particularly CSA with associated Cheyne-Stokes respiration, the recent clinical trial in the heart failure patient population has demonstrated worse cardiovascular outcome in symptomatic patients. SUMMARY: Both OSA and CSA are highly prevalent in patients with heart failure. Effective treatment of OSA with continuous positive airway pressure can improve cardiovascular outcome in these patients. However, recent evidence suggests that adaptive servoventilation cannot be safely recommended as a therapy for CSA in the context of heart failure, as a result of increased risk of cardiovascular mortality.
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The prevalence of OSA among heart failure patients is about 30-50%, while that of central sleep apnea (CSA) is about 25-40%.
“The prevalence of OSA among heart failure patients is about 30-50% while that of central sleep apnea (CSA) is about 25-40%.”
From Sleep: important considerations for the prevention of cardiovascular disease (2016) · cites this paper as [96]
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Sleep: important considerations for the prevention of cardiovascular disease
Grandner, M. A., Alfonso-Miller, P., Fernandez-Mendoza, J., Shetty, S., Shenoy, S., & Combs, D. (2016) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000324 · Cited by 166 · see citing works
- Authors
- Zhai, A. B., Yip, A., & Haddad, H.
- Affiliations
- Ottawa Heart Institute (CA)
- ORCID
- Yip, Amelia
- Venue
- Current Opinion in Cardiology
- Published
- 2016-03
- Volume
- 31
- Issue
- 2
- Pages
- 224-228
- ISSN
- 0268-4705 (ISSN-L)
- OpenAlex
- W2401136257
- Cited by
- 13
- References
- 65
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 2 · 2017: 1 · 2016: 3
- FWCI
- 0.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Keywords
- heart failure, sleep-disordered breathing, obstructive sleep apnea, central sleep apnea, Cheyne-Stokes respiration, adaptive servo-ventilation, continuous positive airway pressure, cardiovascular mortality, bidirectional relationship
- MeSH terms
- Heart Failure, Humans, Sleep Apnea Syndromes, Continuous Positive Airway Pressure, Patient Outcome Assessment
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