Relationship between body mass index, nutrition, strength, and function in elderly individuals with chronic obstructive pulmonary disease
Abstract
In Brief PURPOSE: Individuals with severe chronic obstructive pulmonary disease are frequently characterized as cachectic and suffering from generalized weight loss and muscle wasting. Loss of body mass is associated with disability and premature mortality, and body mass index (BMI) has been used as a marker for nutritional status and to predict survival. This cross-sectional study evaluated the association between BMI (kg/m2), nutritional intake, strength, and function in 19 elderly (70 ± 1 years) men and women (BMI = 27.8 ± 1.1 kg/m2) enrolled in a pulmonary rehabilitation program. METHODS: Three-day prospective diet records were collected and analyzed using Food Processor software. Upper and lower body strength was measured using 1 repetition maximum testing for chest and leg press. Function (endurance, strength, and power) was assessed using the Senior Fitness Test battery (6-minute walk, up-and-go, chair stand, arm curl). RESULTS: BMI was positively associated with upper (P < .05) and lower (P < .01) body strength but was not related to nutrition or function. Total daily caloric (kcal/d), protein (g/d), and carbohydrate (g/d) intakes were positively related to upper body strength (P < .01, P < .01, and P < .05, respectively) and lower body strength (P < .05, P < .05, and P < .05, respectively) and 6-minute walk (P < .05). Fat intake (g/d) was positively related to upper body strength (P < 0.05) alone. CONCLUSIONS: Despite health concerns regarding obesity and overweight, clinicians should consider the impact of BMI and dietary intake before initiating weight loss interventions in patients with chronic obstructive pulmonary disease. In elderly patients with chronic obstructive pulmonary disease, body mass index and nutritional intake were strongly related to strength, but only nutrition was related to function. Results suggest that although adequate long-term nutrition is needed to maintain body mass index and strength, adequate short-term nutrition is needed for function.
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Benton et al. found that higher carbohydrate intakes were associated with higher strength, both in upper and lower body in overweight elderly people.
“Benton et al. found that higher carbohydrate intakes were associated with higher strength, both in upper and lower body in overweight elderly people [54].”
From Identification of factors associated with sarcopenic obesity development: Literature review and expert panel voting (2024) · cites this paper as [54]
Cites
Rabe, K. F., Hurd, S., Anzueto, A., Barnes, P. J., Buist, S. A., Calverley, P., Fukuchi, Y., Jenkins, C., Rodriguez-Roisin, R., van Weel, C., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200703-456so · Cited by 4,925 · see citing works
Rabe, K. F. (2007) · American Journal of Respiratory and Critical Care Medicine · Cited by 2,567 · see citing works
Development and Validation of a Functional Fitness Test for Community-Residing Older Adults
Rikli, R. E., & Jones, C. J. (1999) · Journal of Aging and Physical Activity · doi:10.1123/japa.7.2.129 · Cited by 2,090 · see citing works
Prognostic Value of Nutritional Status in Chronic Obstructive Pulmonary Disease
LANDBO, C., Prescott, E., Lange, P., Vestbo, J., & Almdal, T. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.6.9902115 · Cited by 1,028 · see citing works
Marquis, K., Debigaré, R., Lacasse, Y., Leblanc, P., Jobin, J., Carrier, G., & Maltais, F. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2107031 · Cited by 840 · see citing works
Peripheral Muscle Weakness in Patients with Chronic Obstructive Pulmonary Disease
BERNARD, S., LeBLANC, P., WHITTOM, F., CARRIER, G., JOBIN, J., BELLEAU, R., & MALTAIS, F. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.2.9711023 · Cited by 817 · see citing works
Vestbo, J., Prescott, E., Almdal, T., Dahl, M., Nordestgaard, B. G., Andersen, T., Sørensen, T. I. A., & Lange, P. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200506-969oc · Cited by 642 · see citing works
Trabulsi, J., & Schoeller, D. A. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.281.5.e891 · Cited by 476 · see citing works
Neuhouser, M. L., Tinker, L. F., Shaw, P. A., Schoeller, D. A., Bingham, S. A., Horn, L. V., Beresford, S. A. A., Caan, B. J., Thomson, C. A., Satterfield, S., et al. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn026 · Cited by 355 · see citing works
Prevalence of nutritional depletion in a large out-patient population of patients with COPD
Vermeeren, M. A. P., Creutzberg, E. C., Schols, A. M. W. J., Postma, D. S., Pieters, W. R., Roldaan, A. C., & Wouters, E. F. �. (2006) · Respiratory Medicine · doi:10.1016/j.rmed.2005.11.023 · Cited by 287 · see citing works
The Origins of Cachexia in Acute and Chronic Inflammatory Diseases*
Delano, M. J., & Moldawer, L. L. (2006) · Nutrition in Clinical Practice · doi:10.1177/011542650602100168 · Cited by 197 · see citing works
Slinde, F., Grönberg, A., Engström, C.-P., Rossander-Hulthén, L., & Larsson, S. (2005) · Respiratory Medicine · doi:10.1016/j.rmed.2004.09.024 · Cited by 115 · see citing works
Effect of Supplementing a High-Fat, Low-Carbohydrate Enteral Formula in COPD Patients
Cai, B., Zhu, Y.-J., Ma, Y., Xu, Z., Zao, Y., Wang, J., Lin, Y., & Comer, G. M. (2003) · Nutrition · doi:10.1016/s0899-9007(02)01064-x · Cited by 98 · see citing works
Farber, M. O., & Mannix, E. T. (2000) · Neurologic Clinics · doi:10.1016/s0733-8619(05)70188-2 · Cited by 38 · see citing works
Dietary prescription for chronic obstructive pulmonary disease
Thomas, D. R. (2002) · Clinics in Geriatric Medicine · doi:10.1016/s0749-0690(02)00033-2 · Cited by 10 · see citing works
Nutritional status of COPD patients with acute exacerbation.
Ergün, P., Turay, Ü. Y., Aydoğdu, M., Erdoğan, Y., Biber, Ç., Direk, S. A., & Çağlar, A. (2003) · PubMed · Cited by 7 · see citing works
Flagged first, then by citations
1 of the 17 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Volpi, E., Campbell, W., Dwyer, J., Johnson, M., Jensen, G., Morley, J., & Wolfe, R. (2013) · The journals of gerontology. Series A, Biological sciences and medical sciences · doi:10.1093/gerona/gls229 · Cited by 361 · see citing works
From Current Opinion in Pulmonary Medicine
Blanchette, C. M., Berry, S. R., & Lane, S. J. (2011) · Cited by 262 · see citing works
Karelis, A. D., Messier, V., Suppère, C., Briand, P., & RABASA-LHORET, R. P. R. (2015) · The journal of nutrition health & aging · doi:10.1007/s12603-015-0442-y · Cited by 52 · see citing works
Contribution of anorexia to tissue wasting in cachexia
Molfino, A., Laviano, A., & Fanelli, F. R. (2010) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0b013e32833e4aa5 · Cited by 39 · see citing works
Circuit Training Improvements in Korean Women with Sarcopenia
Jung, W., Kim, Y.-Y., & Park, H. (2019) · Perceptual and Motor Skills · doi:10.1177/0031512519860637 · Cited by 41 · see citing works
Impact of Body Mass Index Change on the Prognosis of Chronic Obstructive Pulmonary Disease
Kim, E. K., Singh, D., Park, J. H., Park, Y. B., Kim, S. I., Park, B., Park, J., Kim, J., Kim, M., Lee, J.-H., et al. (2020) · Respiration · doi:10.1159/000511022 · Cited by 35 · see citing works
Relationship between different protein intake recommendations with muscle mass and muscle strength
Lemieux, F. C., Filion, M.-E., Barbat‐Artigas, S., Karelis, A. D., & Aubertin‐Leheudre, M. (2013) · Climacteric · doi:10.3109/13697137.2013.829440 · Cited by 30 · see citing works
Hanson, C., Bowser, E. K., Frankenfield, D. C., & Piemonte, T. A. (2020) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2019.12.001 · Cited by 29 · see citing works
Pinel, A., Guillet, C., Capel, F., Pouget, M., De Antonio, M., Pereira, B., Topinkova, E., Eglseer, D., Barazzoni, R., Cruz-Jentoft, A. J., et al. (2024) · Clinical Nutrition · doi:10.1016/j.clnu.2024.04.033 · Cited by 24 · see citing works
COPD and Associated Comorbidities: A Review of Current Diagnosis and Treatment
Carlin, B. W. (2012) · Postgraduate Medicine · doi:10.3810/pgm.2012.07.2582 · Cited by 24 · see citing works
Relationship between protein intake and dynapenia in postmenopausal women
Filion, M., Barbat‐Artigas, S., Dupontgand, S., Fex, A., Karelis, A. D., & Aubertin‐Leheudre, M. (2012) · The journal of nutrition health & aging · doi:10.1007/s12603-012-0054-8 · Cited by 20 · see citing works
Dulac, M., Pion, C. H., Lemieux, F. C., Carvalho, L. P., Boutros, G. E. H., Bélanger, M., Gaudreau, P., Chevalier, S., Morais, J. A., Noirez, P., et al. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520001932 · Cited by 17 · see citing works
Advances in chronic obstructive pulmonary disease among older adults
Blanchette, C. M., Berry, S. R., & Lane, S. J. (2010) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0b013e32834316ff · Cited by 17 · see citing works
Xu, L., Sun, X., Zhu, Z., Qiao, J., Mao, S., & Qiu, Y. (2012) · Journal of Spinal Disorders & Techniques · doi:10.1097/bsd.0b013e31825d97df · Cited by 15 · see citing works
Krónikus légzőszervi betegek tápláltsági állapotának vizsgálata – klinikai megfigyelések
Fekete, M., Pongor, V., Fehér, Á., Bálint, M. V., Varga, J. T., & Horváth, I. (2019) · Orvosi Hetilap · doi:10.1556/650.2019.31386 · Cited by 13 · see citing works
Saha, A., Barma, P., Biswas, A., Ghosh, S., Malik, T., Mitra, M., Panchadhyayee, P., Roy, A., & Saha, K. (2013) · The Journal of Association of Chest Physicians · doi:10.4103/2320-8775.123217 · Cited by 11 · see citing works
Pichon, R., Hove, O. V., Ménard, M., Haering, D., & Crétual, A. (2022) · Disability and Rehabilitation · doi:10.1080/09638288.2022.2107083 · Cited by 9 · see citing works
Hirsch, K. R., Tweedell, A. J., Kleinberg, C. R., Gerstner, G. R., Barnette, T. J., Mota, J. A., Smith‐Ryan, A. E., & Ryan, E. D. (2018) · Journal of the American College of Nutrition · doi:10.1080/07315724.2018.1455071 · Cited by 8 · see citing works
Body mass index and its relation to GOLD stage in chronic obstructive pulmonary disease patients
Assal, H. H., & Kamal, E. (2016) · Egyptian Journal of Chest Diseases and Tuberculosis · doi:10.1016/j.ejcdt.2016.01.002 · Cited by 7 · see citing works
Thompson, B. J., Ryan, E. D., Sobolewski, E. J., & Smith‐Ryan, A. E. (2015) · Nutrition Research · doi:10.1016/j.nutres.2015.02.003 · Cited by 5 · see citing works
Rao, Z., Wu, X., Wang, M., & Hu, W. (2012) · PubMed · Cited by 5 · see citing works
Mouri, T., Hatamochi, C., Uchino, J., & Takayama, K. (2020) · Europe PMC (PubMed Central) · doi:10.24546/81012559 · Cited by 4 · see citing works
Bedside Caregivers as Change Agents
Kelly, M. K. (2014) · Critical Care Nursing Clinics of North America · doi:10.1016/j.ccell.2014.02.001 · Cited by 2 · see citing works
Clinical Implications of Overweight and Obesity in Chronic Obstructive Pulmonary Disease
Haagen, E., & Jonker, R. (2011)
Pattern of antiendothelial cell antibodies in patients with chronic obstructive pulmonary disease
Mohamed, R. S. E., El-Batanouny, M. M., Mohamed, A., & Elhadary, S. (2017) · Egyptian Journal of Bronchology · doi:10.4103/1687-8426.203801
Roubertoux, P. L., & Carlier, M. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3777-6_5
(2011) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0b013e3283440e26
Li, R., Cai, L.-L., Hu, W., Lian, L.-R., Meng, W.-Y., Zhang, J., Guo, J., Yao, X., Pan, H., Liu, L., et al. (2023) · Ageing and Cancer Research & Treatment · doi:10.37155/2972-4759-2023-01-01-7
Masaki, M., Yokota, M., Takeuchi, M., Kasahara, M., Maruyama, S., & Sugawara, K. (2025) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2025.05.009
- Authors
- Benton, M. J., Wagner, C. L., & Alexander, J. L.
- Affiliations
- Valdosta State University (US)
- Corresponding author
- Benton, Melissa J.
- Venue
- Journal of Cardiopulmonary Rehabilitation and Prevention
- Published
- 2010-07
- Volume
- 30
- Issue
- 4
- Pages
- 260-263
- ISSN
- 1932-7501 (ISSN-L)
- OpenAlex
- W2313951913
- Cited by
- 29
- References
- 17
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2020: 4 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 1 · 2013: 2 · 2012: 5
- FWCI
- 2.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Cardiopulmonary Rehabilitation and Prevention (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Keywords
- chronic obstructive pulmonary disease, body mass index, nutritional intake, muscle strength, physical function, elderly patients, pulmonary rehabilitation, dietary fat intake, protein intake, obesity, cachexia, weight loss interventions, 6-minute walk test
- MeSH terms
- Aged, Aged, 80 and over, Energy Intake, Cross-Sectional Studies, Energy Metabolism, Female, Humans, Leg, Male, Middle Aged, Nutritional Status, Obesity, Physical Endurance, Physical Fitness, Prospective Studies, Spirometry, Statistics as Topic, Thorax, Weight Loss, Body Mass Index, Muscle, Skeletal, Pulmonary Disease, Chronic Obstructive, Overweight, Muscle Strength
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