Cited by 80Aging, Health, and DisabilityFrailty in Older AdultsDementia and Cognitive Impairment Research

Physical disability and depressive symptomatology in an elderly population: a complex relationship—the Italian longitudinal study on aging (ILSA)

Dalle Carbonare, Luca, Maggi, Stefania, Noale, Marianna, Giannini, Sandro, Rozzini, Renzo, Lo Cascio, Vincenzo, Crepaldi, Gaetano·2009·The American Journal of Geriatric Psychiatry

Abstract

Objectives Depressive symptoms (DS) are very frequent in elderly individuals and are associated with negative outcomes. This study was undertaken to evaluate whether DS predict physical disability in this population.Methods A prospective,community-based cohort study, this work included 5,632 individuals aged 65-84 years, who were recruited from the demographic registries of eight Italian municipalities in 1992. The complete data of 3,256 subjects were collected and analyzed. DS were assessed using the Geriatric Depression Scale with a score > or = 10/30 indicating DS. All traditional risk factors for disability established by questionnaires and physical examinations were assessed at baseline. The outcomes were self-reported disability on the activities of daily living (ADL) test and the performance-based physical function assessment (Physical Performance Tests, PPT). The contribution of the predictive variables to the outcomes evaluated after a mean follow-up of 3.5 +/- 0.4 years was assessed using hierarchical logistic nested models.Results Baseline DS was associated with higher rates of ADL disability (odds ratio [OR] 1.73, 95%confidence interval [CI] 1.12-2.66) and PPT disability (OR 1.83, 95% CI 1.17-2.85)in men and with ADL disability (OR 1.81, 95% CI 1.28 -2.55) in women. The independent predictors of PPT disability in women were arthritis (OR 2.13, 95% CI 1.28 -3.53) and age (OR 1.09; 95% CI 1.03-1.15).Conclusions This study provides evidence that older persons who report DS are at higher risk of subsequent physical decline. In women, arthritis is a more powerful predictor of preclinical disability, as measured by PPT.

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Crossref · 10.1097/jgp.0b013e31818af817

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Authors
Dalle Carbonare, L., Maggi, S., Noale, M., Giannini, S., Rozzini, R., Lo Cascio, V., & Crepaldi, G.
Affiliations
  • National Research Council (IT)
  • University of Padua (IT)
  • Fondazione Poliambulanza Istituto Ospedaliero (IT)
Venue
The American Journal of Geriatric Psychiatry
Publisher
Elsevier BV
Published
2009-02
Volume
17
Issue
2
Pages
144-154
ISSN
1064-7481 (ISSN-L)
OpenAlex
W2011344007
Cited by
80
References
38
Citations by year
2025: 2 · 2024: 3 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 5 · 2017: 7 · 2016: 2 · 2015: 6 · 2014: 6 · 2013: 11 · 2012: 7
FWCI
10.37
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Geriatric Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • CINECA IRIS Institutial Research Information System (University of Genoa) (submittedVersion)
  • Padua Research Archive (University of Padova) (submittedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
  • Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords
depressive symptoms, physical disability, older adults, activities of daily living, physical performance, arthritis, sex differences, geriatric depression, disability risk factors, Italian Longitudinal Study on Aging
MeSH terms
Activities of Daily Living, Aged, Aged, 80 and over, Arthritis, Cognition Disorders, Depression, Female, Persons with Disabilities, Humans, Italy, Longitudinal Studies, Male, Motor Activity, Prospective Studies, Psychiatric Status Rating Scales, Risk Factors, Self-Assessment, Sex Factors, Cohort Studies, Geriatric Assessment

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