Cited by 296Dementia and Cognitive Impairment ResearchPhysical Activity and HealthCognitive Functions and Memory

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

The effects of exercise on cognition in older adults with and without cognitive decline: a systematic review.

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Uffelen, Jannique G Z van, Chin A Paw, Marijke J M, Hopman-Rock, Marijke, Mechelen, Willem van·2008·Clinical Journal of Sport Medicine

Abstract

OBJECTIVE: To systematically review the effect of physical exercise on cognition in older adults with and without cognitive decline. DATA SOURCES: : Randomized controlled trials were identified by literature searches in PubMed, EMBASE, CENTRAL, PsycINFO, and AgeLine. STUDY SELECTION: Papers were included on the basis of predefined inclusion criteria. DATA EXTRACTION: Data on study population, exercise intervention, and effectiveness were extracted. Two independent reviewers assessed methodological quality. DATA SYNTHESIS: Twenty-three studies were included-15 among cognitively healthy subjects and 8 among subjects with cognitive decline. Seven studies were qualified as high-quality studies, 2 in cognitively healthy subjects and 5 in subjects with cognitive decline. In cognitively healthy subjects, significant beneficial intervention effects were observed in 5 studies on information processing, executive function, or memory. Interventions in these studies included aerobic exercise only (n = 2); strength exercise (n = 1); strength and balance exercise (n = 1); or all-round exercise including aerobic, strength, balance and flexibility training (n = 1). In subjects with cognitive decline, 5 studies observed beneficial effects on general cognition, executive functions, and memory. Interventions included aerobic (n = 3) or strength exercise combined with flexibility or balance exercise (n = 2). CONCLUSIONS: Beneficial effects of various exercise programs on aspects of cognition have been observed in studies among subjects with and without cognitive decline. The majority of the studies, however, did not find any effect. The small number of included studies; lack of high-quality studies; and the large variability in study populations, exercise protocols, and outcome measures complicate interpretation of the results. More high-quality trials are needed to assess the effects of different types of exercise on cognitive function in older adults with and without cognitive decline.

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Metadata

Authors
Uffelen, J. G. Z. V., Chin A Paw, M. J. M., Hopman-Rock, M., & Mechelen, W. V.
Affiliations
Netherlands Organisation for Applied Scientific Research (NL)
Corresponding author
Hopman-Rock, Marijke
Venue
Clinical Journal of Sport Medicine
Published
2008-11
Volume
18
Issue
6
Pages
486-500
ISSN
1050-642X (ISSN-L)
OpenAlex
W2064404113
Cited by
296
References
50
Citations by year
2026: 8 · 2025: 7 · 2024: 10 · 2023: 15 · 2022: 10 · 2021: 21 · 2020: 21 · 2019: 19 · 2018: 12 · 2017: 19 · 2016: 15 · 2015: 30 · 2014: 22 · 2013: 25 · 2012: 18
FWCI
1.85
Type
journal article
Language
en
Open access
Locations
  • Clinical Journal of Sport Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
  • Victoria University Research Repository (Victoria University) (submittedVersion)
  • Lirias (submittedVersion, other-oa)
  • TNO Repository (submittedVersion)
  • Repository hosted by TU Delft Library (TU Delft) (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
Funders
Vrije Universiteit Amsterdam
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
Keywords
physical activity, cognitive function, older adults, cognitive decline, aerobic exercise, resistance training, balance training, flexibility training, executive function, memory, information processing
MeSH terms
Aging, Cognition, Humans, Exercise

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