Cited by 359Nutrition and Health in AgingMuscle Physiology and DisordersFrailty in Older Adults

The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.

Functional consequences of sarcopenia and dynapenia in the elderly

Open access

Clark, Brian C, Manini, Todd M·2010·Current Opinion in Clinical Nutrition and Metabolic Care

DOI 10.1097/mco.0b013e328337819ePMC PMC2895460

Open this paper in CoChat — free account

Abstract

PURPOSE OF REVIEW: The economic burden due to the sequela of sarcopenia (muscle wasting in the elderly) are staggering and rank similarly to the costs associated with osteoporotic fractures. In this article, we discuss the societal burden and determinants of the loss of physical function with advancing age, the physiologic mechanisms underlying dynapenia (muscle weakness in the elderly), and provide perspectives on related critical issues to be addressed. RECENT FINDINGS: Recent epidemiological findings from longitudinal aging studies suggest that dynapenia is highly associated with both mortality and physical disability even when adjusting for sarcopenia indicating that sarcopenia may be secondary to the effects of dynapenia. These findings are consistent with the physiologic underpinnings of muscle strength, as recent evidence demonstrates that alterations in muscle quantity, contractile quality and neural activation all collectively contribute to dynapenia. SUMMARY: Although muscle mass is essential for regulation of whole body metabolic balance, overall neuromuscular function seems to be a critical factor for maintaining muscle strength and physical independence in the elderly. The relative contribution of physiologic factors contributing to muscle weakness are not fully understood and further research is needed to better elucidate these mechanisms between muscle groups and across populations.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1097/mco.0b013e328337819e

Cites

53 of 53 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Epidemiology of Sarcopenia among the Elderly in New Mexico
Baumgartner, R. N., Koehler, K. M., Gallagher, D., Romero, L., Heymsfield, S. B., Ross, R. R., Garry, P. J., & Lindeman, R. D. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009520 · Cited by 4,004
The Loss of Skeletal Muscle Strength, Mass, and Quality in Older Adults: The Health, Aging and Body Composition Study
Goodpaster, B. H., Park, S. W., Harris, T. B., Kritchevsky, S. B., Nevitt, M., Schwartz, A. V., Simonsick, E. M., Tylavsky, F. A., Visser, M., Newman, A. B., et al. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.10.1059 · Cited by 3,083
Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery
Guralnik, J. M., Ferrucci, L., Pieper, C. F., Leveille, S. G., Markides, K. S., Ostir, G. V., Studenski, S., Berkman, L. F., & Wallace, R. B. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.4.m221 · Cited by 2,898
Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia
Lauretani, F., Russo, C. R., Bandinelli, S., Bartali, B., Cavazzini, C., Di Iorio, A., Corsi, A. M., Rantanen, T., Guralnik, J. M., & Ferrucci, L. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00246.2003 · Cited by 1,946
Strength, But Not Muscle Mass, Is Associated With Mortality in the Health, Aging and Body Composition Study Cohort
Newman, A. B., Kupelian, V., Visser, M., Simonsick, E. M., Goodpaster, B. H., Kritchevsky, S. B., Tylavsky, F. A., Rubin, S. M., Harris, T. B., & on Behalf of the Health, A. A. B. C. S. I. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.1.72 · Cited by 1,692
The healthcare costs of sarcopenia in the United States
Janssen, I., Shepard, D. S., Katzmarzyk, P. T., & Roubenoff, R. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52014.x · Cited by 1,546
Longitudinal study of muscle strength, quality, and adipose tissue infiltration
Delmonico, M. J., Harris, T. B., Visser, M., Park, S. W., Conroy, M. B., Velasquez-Mieyer, P., Boudreau, R., Manini, T. M., Nevitt, M., Newman, A. B., et al. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28047 · Cited by 1,446
Self-citation
Muscle Mass, Muscle Strength, and Muscle Fat Infiltration as Predictors of Incident Mobility Limitations in Well-Functioning Older Persons
Visser, M., Goodpaster, B. H., Kritchevsky, S. B., Newman, A. B., Nevitt, M., Rubin, S. M., Simonsick, E. M., Harris, T. B., & Study, F. T. H. A. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.3.324 · Cited by 1,403
Medical Expenditures for the Treatment of Osteoporotic Fractures in the United States in 1995: Report from the National Osteoporosis Foundation
Ray, N. F., Chan, J. K., Thamer, M., & Melton, L. J. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.1.24 · Cited by 1,281
Summary comments
Rosenberg, I. H. (1989) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/50.5.1231 · Cited by 1,234

Flagged first, then by citations

Show all 53 references

Research works printed but not linked: 1

Russ, 2009, Med Sci Sports Exercise, 41, Abstract

Sorted by citations

Items 101–200 of 357

The Current Understanding of Sarcopenia
Delmonico, M. J., & Beck, D. T. (2015) · American Journal of Lifestyle Medicine · doi:10.1177/1559827615594343 · Cited by 53
Usefulness of Preclinical Models for Assessing the Efficacy of Late-Life Interventions for Sarcopenia
Carter, C. S., Marzetti, E., Leeuwenburgh, C., Manini, T. M., Foster, T. C., Groban, L., Scarpace, P. J., & Morgan, D. (2011) · The Journals of Gerontology Series A · doi:10.1093/gerona/glr042 · Cited by 45
Terminal Schwann Cell Aging: Implications for Age-Associated Neuromuscular Dysfunction
Fuertes-Álvarez, S., & Izeta, A. (2021) · Aging and Disease · doi:10.14336/ad.2020.0708 · Cited by 46
The correlation of muscle thickness and pennation angle assessed by ultrasound with sarcopenia in elderly Chinese community dwellers
Zhu, S., Lin, W., Chen, S., Qi, H., Wang, S., Zhang, A., Cai, J., Lai, B., Sheng, Y., & Ding, G. (2019) · Clinical Interventions in Aging · doi:10.2147/cia.s201777 · Cited by 47
Neuroprotective effects of exercise on the aging human neuromuscular system
Allen, M. D., Dalton, B. H., Gilmore, K. J., McNeil, C. J., Doherty, T. J., Rice, C. L., & Power, G. A. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111465 · Cited by 47
Effects of Exergames and Protein Supplementation on Body Composition and Musculoskeletal Function of Prefrail Community-Dwelling Older Women: A Randomized, Controlled Clinical Trial
Biesek, S., Vojciechowski, A. S., Filho, J. M., Ferreira, A. C. R. D. M., Borba, V. Z. C., Rabito, E. I., & Gomes, A. R. S. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18179324 · Cited by 44
Skeletal muscle dysfunction with advancing age
Pabla, P., Jones, E. J., Piasecki, M., & Phillips, B. E. (2024) · Clinical Science · doi:10.1042/cs20231197 · Cited by 50
A Review of Combined Training Studies in Older Adults According to a New Categorization of Conventional Interventions
Torre, M. M., & Temprado, J.-J. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.808539 · Cited by 43
Rehabilitation and Total Joint Arthroplasty
Westby, M. D. (2012) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2012.05.005 · Cited by 40
The association between sarcopenia and fracture in middle-aged and elderly people: A systematic review and meta-analysis of cohort studies
Chen, H., Ma, J., Liu, A., Cui, Y., & Ma, X. (2020) · Injury · doi:10.1016/j.injury.2020.02.072 · Cited by 39
Nutrition and Physical Therapy: A Position Paper by the Physical Therapist Section of the Japanese Association of Rehabilitation Nutrition (Secondary Publication)
Inoue, T., Iida, Y., Takahashi, K., Shirado, K., Nagano, F., Miyazaki, S., Takeuchi, I., Yoshimura, Y., Momosaki, R., Maeda, K., et al. (2022) · JMA Journal · doi:10.31662/jmaj.2021-0201 · Cited by 37
Development and validation of anthropometric equations to estimate appendicular muscle mass in elderly women
Pereira, P. M. G., da Silva, G. A., Júnior, G. M. S., Petróski, E. L., & Geraldes, A. A. R. (2013) · Nutrition Journal · doi:10.1186/1475-2891-12-92 · Cited by 38
The Frequency of Low Muscle Mass and Its Overlap With Low Bone Mineral Density and Lipodystrophy in Individuals With HIV—A Pilot Study Using DXA Total Body Composition Analysis
Buehring, B., Kirchner, E., Sun, Z., & Calabrese, L. H. (2011) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2011.10.003 · Cited by 39
Independent and combined effect of home-based progressive resistance training and nutritional supplementation on muscle strength, muscle mass and physical function in dynapenic older adults with low protein intake: A randomized controlled trial
Bastone, A. D. C., Nobre, L. N., Moreira, B. D. S., Rosa, I. F., Ferreira, G. B., Santos, D. D. L., Monteiro, N. K. S. S., Alves, M. D., Gandra, R. A., & de Lira, E. M. (2020) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2020.104098 · Cited by 37
Signatures and Clinical Significance of Amino Acid Flux in Sarcopenia: A Systematic Review and Meta-Analysis
Dai, M., Lin, T., Yue, J., & Dai, L. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.725518 · Cited by 37
Short-term, high-fat diet accelerates disuse atrophy and protein degradation in a muscle-specific manner in mice.
Roseno, S. L., Davis, P. R., Bollinger, L. M., Powell, J. J. S., Witczak, C. A., & Brault, J. J. (2015) · Nutrition & Metabolism · doi:10.1186/s12986-015-0037-y · Cited by 36
Effects of Traditional and Pyramidal Resistance Training Systems on Muscular Strength, Muscle Mass, and Hormonal Responses in Older Women: A Randomized Crossover Trial
Ribeiro, A. S., Schoenfeld, B. J., Fleck, S. J., Pina, F. L. C., do Nascimento, M. A., & Cyrino, E. S. (2016) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001653 · Cited by 35
Selection of Resistance Exercises for Older Individuals: The Forgotten Variable
Ribeiro, A. S., Nunes, J. P., & Schoenfeld, B. J. (2020) · Sports Medicine · doi:10.1007/s40279-020-01260-5 · Cited by 40
The Impact of Low Muscle Mass Definition on the Prevalence of Sarcopenia in Older Australians
Yu, S., Appleton, S., Adams, R., Chapman, I., Wittert, G., Visvanathan, T., & Visvanathan, R. (2014) · BioMed Research International · doi:10.1155/2014/361790 · Cited by 38
Clinical Trials on Sarcopenia: Methodological Issues Regarding Phase 3 Trials
van Kan, G. A., Chumlea, W. C., Guyonnet, S., Houles, M., Dupuy, C., Rolland, Y., & Vellas, B. J. (2011) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2011.03.010 · Cited by 34
Prevalence and factors associated with sarcopenia and dynapenia in elderly people
Neves, T., Ferriolli, E., Lopes, M. B. M., Souza, M. G. C., Fett, C. A., & Fett, W. C. R. (2018) · Journal of Frailty Sarcopenia and Falls · doi:10.22540/jfsf-03-194 · Cited by 33
Diabetic Myopathy and Mechanisms of Disease
Hernández‐Ochoa, E. O., & Vanegas, O. C. (2015) · Biochemistry & Pharmacology Open Access · doi:10.4172/2167-0501.1000e179 · Cited by 32
Physical Activity Protects Men but Not Women for Sarcopenia Development
Rivera, J. D. J., Fonseca-Sánchez, M. A., Rodriguez, P., Garcia, J. M., Lara, I. P., Aristi, G., Flores-Luce, A., García, L., Trujillo, Y., & Queipo, G. (2016) · Gerontology and Geriatric Medicine · doi:10.1177/2333721416667879 · Cited by 32
Sarcopenia and piscines: the case for indeterminate-growing fish as unique genetic model organisms in aging and longevity research
Froehlich, J. M., Fowler, Z. G., Galt, N. J., Smith, D. L., & Biga, P. R. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00159 · Cited by 33
Exercise capacity, physical activity, and morbidity
Brunjes, D. L., Kennel, P. J., & Schulze, P. C. (2017) · Heart Failure Reviews · doi:10.1007/s10741-016-9592-1 · Cited by 31
Reliability and Validity of the Floor Transfer Test as a Measure of Readiness for Independent Living Among Older Adults
Ardali, G., Brody, L. T., States, R. A., & Godwin, E. M. (2017) · Journal of Geriatric Physical Therapy · doi:10.1519/jpt.0000000000000142 · Cited by 29
Body mass index, performance on activities of daily living and cognition: analysis in two different populations
Borda, M. G., Venegas‐Sanabria, L. C., Garcia-Cifuentes, E. R., Arteaga, R. C. G., Cano, C. A., Tovar, D., Aarsland, V., Khalifa, K. N., Jaramillo-Jiménez, A., Aarsland, D., et al. (2021) · BMC Geriatrics · doi:10.1186/s12877-021-02127-8 · Cited by 30
Association of plasma FGF21 levels with muscle mass and muscle strength in a national multicentre cohort study: Korean Frailty and Aging Cohort Study
Roh, E., Hwang, S. Y., Yoo, H. J., Baik, S. H., Cho, B., Park, Y. S., Kim, H. J., Lee, S., Kim, B., Jang, H. C., et al. (2021) · Age and Ageing · doi:10.1093/ageing/afab178 · Cited by 31
Relationship between different protein intake recommendations with muscle mass and muscle strength
Lemieux, F. C., Filion, M.-E., Barbat‐Artigas, S., Karelis, A. D., & Aubertin‐Leheudre, M. (2013) · Climacteric · doi:10.3109/13697137.2013.829440 · Cited by 30
Association Between Obesity and Falls Among Korean Adults
Kim, S. Y., Kim, M.-S., Sim, S., Park, B., & Choi, H. G. (2016) · Medicine · doi:10.1097/md.0000000000003130 · Cited by 30
A Randomized Trial of the Effects of Dietary n3-PUFAs on Skeletal Muscle Function and Acute Exercise Response in Healthy Older Adults
Kunz, H., Michie, K. L., Gries, K. J., Zhang, X., Ryan, Z. C., & Lanza, I. R. (2022) · Nutrients · doi:10.3390/nu14173537 · Cited by 37
Muscle function in aged women in response to a water‐based exercises program and progressive resistance training
Bento, P. C. B., & Rodacki, A. L. F. (2014) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.12418 · Cited by 28
Upper Limb Strength and Muscle Volume in Healthy Middle-Aged Adults
Saul, K. R., Vidt, M. E., Gold, G. E., & Murray, W. M. (2015) · Journal of Applied Biomechanics · doi:10.1123/jab.2014-0177 · Cited by 28
Functional Independence in the Community Dwelling Older People: a Scoping Review
Molenaar, E., Barten, D., Velde, S. J. T., van der Schoot, L., Bleijenberg, N., de Wit, N. J., & Veenhof, C. (2020) · Journal of Population Ageing · doi:10.1007/s12062-020-09315-1 · Cited by 30
Is handgrip strength normalized to body weight a useful tool to identify dynapenia and functional incapacity in post-menopausal women?
Dulac, M., Boutros, G. E. H., Pion, C. H., Barbat‐Artigas, S., Gouspillou, G., & Aubertin‐Leheudre, M. (2016) · Brazilian Journal of Physical Therapy · doi:10.1590/bjpt-rbf.2014.0184 · Cited by 27
Effects of Different Weekly Sets-Equated Resistance Training Frequencies on Muscular Strength, Muscle Mass, and Body Fat in Older Women
Pina, F. L. C., Nunes, J. P., Schoenfeld, B. J., do Nascimento, M. A., Gerage, A. M., Januário, R. S. B., Carneiro, N. H., Cyrino, E. S., & de Oliveira, A. R. (2019) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003130 · Cited by 27
Effects of exercise training on neuromuscular junctions and their active zones in young and aged muscles
Deschenes, M. R., Tufts, H. L., Oh, J., Li, S., Noronha, A. L., & Adan, M. A. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.07.001 · Cited by 27
Does skeletal muscle morphology or functional performance better explain variance in fast gait speed in older adults?
Komforti, D., Joffe, C., Magras, A., Peller, A., Garbe, E., Garib, R., Trapuzzano, A., Dawson, N., & Stock, M. S. (2021) · Aging Clinical and Experimental Research · doi:10.1007/s40520-020-01596-y · Cited by 25
Dynapenia in all-cause mortality and its relationship with sedentary behavior in community-dwelling older adults
Silva, R. R., Galvão, L. L., Meneguci, J., Santos, D. D. A. T., Júnior, J. S. V., & Tribess, S. (2022) · Sports Medicine and Health Science · doi:10.1016/j.smhs.2022.09.002 · Cited by 25
Revista Española de Geriatría y Gerontología
Santos, R. P., Torres, C. F., Martín‐Arranz, M. D., de Parga, J. M. S., & Martínez, M. A. (2016) · Cited by 26
Regulation of gene expression mediating indeterminate muscle growth in teleosts
Ahammad, A. K. S., Md., A., Asakawa, S., Watabe, S., & Kinoshita, S. (2015) · Mechanisms of Development · doi:10.1016/j.mod.2015.02.006 · Cited by 25
Effects of resistance training on muscle strength, insulin-like growth factor-1, and insulin-like growth factor-binding protein-3 in healthy elderly subjects: a systematic review and meta-analysis of randomized controlled trials
Amiri, N., Fathei, M., & Mosaferi Ziaaldini, M. (2021) · Hormones · doi:10.1007/s42000-020-00250-6 · Cited by 25
Preserved Capacity for Adaptations in Strength and Muscle Regulatory Factors in Elderly in Response to Resistance Exercise Training and Deconditioning
Fritzen, A. M., Thøgersen, F. B., Qadri, K. A. N., Krag, T. O. B., Sveen, M., Vissing, J., & Jeppesen, T. D. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9072188 · Cited by 26
Appendicular Muscle Mass, Thigh Intermuscular Fat Infiltration, and Risk of Fall in Postmenopausal Osteoporotic Elder Women
Vitale, J. A., Messina, C., Albano, D., Fascio, E., Galbusera, F., Corbetta, S., Sconfienza, L. M., & Banfi, G. (2021) · Gerontology · doi:10.1159/000513597 · Cited by 26
Lower-Extremity Force Decrements Identify Early Mobility Decline Among Community-Dwelling Older Adults
Marko, M., Neville, C., Prince, M. A., & Ploutz‐Snyder, L. L. (2012) · Physical Therapy · doi:10.2522/ptj.20110239 · Cited by 24
Analysis of effects of loading and postural demands on upper limb reaching in older adults using statistical parametric mapping
Li, X., Santago, A. C., Vidt, M. E., & Saul, K. R. (2016) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2016.06.018 · Cited by 27
Formoterol, a Highly β2-Selective Agonist, Induces Gender-Dimorphic Whole Body Leucine Metabolism in Humans
Lee, P. Y. K., Birzniece, V., Umpleby, A. M., Poljak, A., & Ho, K. K. Y. (2014) · Metabolism · doi:10.1016/j.metabol.2014.12.005 · Cited by 25
Influence of Resistance Training Exercise Order on Muscle Strength, Hypertrophy, and Anabolic Hormones in Older Women: A Randomized Controlled Trial
Tomeleri, C. M., Ribeiro, A. S., Nunes, J. P., Schoenfeld, B. J., de Souza, M. F., Bortoloti, D. S., Paulo, S., Cavaglieri, C. R., Cunha, P. M., Venturini, D., et al. (2019) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003147 · Cited by 24
Post-operative electrical muscle stimulation attenuates loss of muscle mass and function following major abdominal surgery in older adults: a split body randomised control trial
Hardy, E., Hatt, J., Doleman, B., Smart, T., Piasecki, M., Lund, J. N., & Phillips, B. E. (2022) · Age and Ageing · doi:10.1093/ageing/afac234 · Cited by 24
Therapeutic Applications of Type 2 Diabetes Mellitus Drug Metformin in Patients with Osteoarthritis
Song, P., Hwang, J. S., Park, H. C., Kim, K. K., Son, H., Kim, Y., & Lee, K. M. (2021) · Pharmaceuticals · doi:10.3390/ph14020152 · Cited by 25
The application of different appendicular skeletal muscle cutoff points and research definitions associated with health-related quality of life in Korean older people: data from KNHANES 2008–2011
Kim, Y., Joh, J., Kim, S., Hwang, H., & Shin, I. (2014) · BMC Geriatrics · doi:10.1186/1471-2318-14-144 · Cited by 23
Follistatin-induced muscle hypertrophy in aged mice improves neuromuscular junction innervation and function
Iyer, C. C., Chugh, D., Bobbili, P. J., Blatnik, A. J., Crum, A. E., Yi, A. F., Kaspar, B. K., Meyer, K., Burghes, A. H. M., & Arnold, W. D. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.03.005 · Cited by 22
The effect of progressive resistance training on lean body mass in post-treatment cancer patients – A systematic review
Lønbro, S. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.07.008 · Cited by 23
Impact of Mild Hypohydration on Muscle Endurance, Power, and Strength in Healthy, Active Older Men
Goulet, E. D. B., Mélançon, M. O., Lafrenière, D., Paquin, J., Maltais, M. L., & Morais, J. A. (2017) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000001857 · Cited by 22
High-Velocity Quadriceps Exercises Compared to Slow-Velocity Quadriceps Exercises Following Total Knee Arthroplasty: A Randomized Clinical Study
Doerfler, D., Gurney, B., Mermier, C. M., Rauh, M. J., Black, L., & Andrews, R. (2015) · Journal of Geriatric Physical Therapy · doi:10.1519/jpt.0000000000000071 · Cited by 21
A Randomized Controlled Pilot Exercise and Protein Effectiveness Supplementation Study (EXPRESS) on Reducing Frailty Risk in Community-Dwelling Older People
Jadczak, A. D., Visvanathan, R., Barnard, R., & Luscombe‐Marsh, N. D. (2021) · Journal of Nutrition in Gerontology and Geriatrics · doi:10.1080/21551197.2021.1886222 · Cited by 21
Functional capacity depends on lower limb muscle strength rather than on abdominal obesity in active postmenopausal women
Dulac, M., Carvalho, L. P., & Aubertin‐Leheudre, M. (2017) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000000970 · Cited by 21
The perspectives of pre-frail and frail older people on being advised about exercise: a qualitative study
Jadczak, A. D., Dollard, J., Mahajan, N., & Visvanathan, R. (2017) · Family Practice · doi:10.1093/fampra/cmx108 · Cited by 21
Indices calculated by serum creatinine and cystatin C as predictors of liver damage, muscle strength and sarcopenia in liver disease
Ichikawa, T., Miyaaki, H., Miuma, S., Motoyoshi, Y., Yamashima, M., Yamamichi, S., Koike, M., Takahashi, Y., Honda, T., Yajima, H., et al. (2020) · Biomedical Reports · doi:10.3892/br.2020.1273 · Cited by 21
Can self-report instruments of shoulder function capture functional differences in older adults with and without a rotator cuff tear?
Vidt, M. E., Santago, A. C., Hegedus, E. J., Marsh, A. P., Tuohy, C. J., Poehling, G. G., Freehill, M. T., Miller, M. E., & Saul, K. R. (2015) · Journal of Electromyography and Kinesiology · doi:10.1016/j.jelekin.2015.06.009 · Cited by 21
Characteristics of Older Adults Who Are Unable to Perform a Floor Transfer: Considerations for Clinical Decision-Making
Ardali, G., States, R. A., Brody, L. T., & Godwin, E. M. (2018) · Journal of Geriatric Physical Therapy · doi:10.1519/jpt.0000000000000189 · Cited by 19
Relationship between protein intake and dynapenia in postmenopausal women
Filion, M., Barbat‐Artigas, S., Dupontgand, S., Fex, A., Karelis, A. D., & Aubertin‐Leheudre, M. (2012) · The journal of nutrition health & aging · doi:10.1007/s12603-012-0054-8 · Cited by 20
Muscle Mechanography: A Novel Method to Measure Muscle Function in Older Adults
Taani, M. H., Kovach, C. R., & Buehring, B. (2017) · Research in Gerontological Nursing · doi:10.3928/19404921-20161209-03 · Cited by 20
Microbiopsy Sampling for Examining Age-Related Differences in Skeletal Muscle Fiber Morphology and Composition
Hester, G. M., VanDusseldorp, T. A., Ha, P. L., Kiani, K., Olmos, A. A., Jabbari, M., Kalladanthyil, S., An, S., Bailly, A. R., Dalton, B. E., et al. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2021.756626 · Cited by 19
Exercise-Based Interventions to Counteract Skeletal Muscle Mass Loss in People with Cancer: Can We Overcome the Odds?
Bland, K. A., Kouw, I. W. K., van Loon, L. J. C., Zopf, E. M., & Fairman, C. M. (2022) · Sports Medicine · doi:10.1007/s40279-021-01638-z · Cited by 19
The effects of physical activity and exercise therapy on frail elderly depression: A narrative review
Zhang, Y., & Jiang, X. (2023) · Medicine · doi:10.1097/md.0000000000034908 · Cited by 26
The mediating role of inflammaging between mitochondrial dysfunction and sarcopenia in aging: a review.
Xu, X., & Wen, Z. (2023) · PubMed Central · Cited by 21
Are body fat and inflammatory markers independently associated with age-related muscle changes?
Nascimento, C. M. C., Cardoso, J. D. F. Z., de Jesus, I. T. M., Orlandi, F. D. S., Costa-Guarisco, L. P., Gomes, G. A. D. O., dos Santos‐Orlandi, A. A., Vasilceac, F. A., Pavarini, S. C. I., Gramani‐Say, K., et al. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.09.021 · Cited by 19
High Intensity Interval Training (HIIT) as a Potential Countermeasure for Phenotypic Characteristics of Sarcopenia: A Scoping Review
Hayes, L. D., Elliott, B., Yasar, Z., Bampouras, T. M., Sculthorpe, N. F., Sanal‐Hayes, N. E. M., & Hurst, C. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.715044 · Cited by 21
Effects of different strength training volumes and subsequent detraining on strength performance in aging adults
Bezerra, E. D. S., Diefenthaeler, F., Sakugawa, R. L., Cadore, E. L., Izquierdo, M., & Moro, A. R. P. (2019) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2019.01.010 · Cited by 17
Prevalence and risk factors of possible sarcopenia in patients with subacute stroke
Kim, Y. H., & Choi, Y. (2023) · PLoS ONE · doi:10.1371/journal.pone.0291452 · Cited by 18
Effect of Interaction Between Dynapenic Component of the European Working Group on Sarcopenia in Older People Sarcopenia Criteria and Obesity on Activities of Daily Living in the Elderly
Kim, Y., Kim, S. Y., Joh, J., & Hwang, H. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.12.010 · Cited by 18
Effects of Modified Pyramid System on Muscular Strength and Hypertrophy in Older Women
dos Santos, L., Ribeiro, A., Cavalcante, E., Nabuco, H., Antunes, M., Schoenfeld, B., & Cyrino, E. (2018) · International Journal of Sports Medicine · doi:10.1055/a-0634-6454 · Cited by 18
Psychosocial Factors Associated With Reduced Muscle Mass, Strength, and Function in Residential Care Apartment Complex Residents
Taani, M. H., Siglinsky, E., Kovach, C. R., & Buehring, B. (2018) · Research in Gerontological Nursing · doi:10.3928/19404921-20180810-02 · Cited by 18
Effects of slow- v. fast-digested protein supplementation combined with mixed power training on muscle function and functional capacities in older men
Dulac, M., Pion, C. H., Lemieux, F. C., Carvalho, L. P., Boutros, G. E. H., Bélanger, M., Gaudreau, P., Chevalier, S., Morais, J. A., Noirez, P., et al. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520001932 · Cited by 17
AAV1.NT-3 gene therapy prevents age-related sarcopenia
Özeş, B., Tong, L., Myers, M., Moss, K., Ridgley, A., & Sahenk, Z. (2023) · Aging · doi:10.18632/aging.204577 · Cited by 17
Definición y evolución del concepto de sarcopenia
Tocino, M. L. S., Cigarrán, S., Ureña, P., González‐Casaus, M. L., Mas, S., Iguacel, C. G., Ortíz, A., & Parra, E. G. (2023) · Nefrología · doi:10.1016/j.nefro.2023.08.001 · Cited by 27
Αcute effects of essential amino acid gel-based and whey protein supplements on appetite and energy intake in older women
Butterworth, M., Lees, M. J., Harlow, P., Hind, K., Duckworth, L. C., & Ispoglou, T. (2019) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2018-0650 · Cited by 17
Effects of β-hydroxy-β-methylbutyrate (HMB) supplementation in addition to multicomponent exercise in adults older than 70 years living in nursing homes, a cluster randomized placebo-controlled trial: the HEAL study protocol
on behalf of the HEAL study group, Courel‐Ibáñez, J., & Pallarés, J. G. (2019) · BMC Geriatrics · doi:10.1186/s12877-019-1200-5 · Cited by 17
Corticospinal Control of Human Locomotion as a New Determinant of Age-Related Sarcopenia: An Exploratory Study
Gennaro, F., Maino, P., Kaelin‐Lang, A., Bock, K. D., & de Bruin, E. D. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9030720 · Cited by 18
Presence of dynapenia and association with anthropometric variables in cancer patients
Rechinelli, A. B., Marques, I. L., Viana, E. C. R. D. M., Oliveira, I. D. S., de Souza, V. F., Petarli, G. B., Marques-Rocha, J. L., & Guandalini, V. R. (2020) · BMC Cancer · doi:10.1186/s12885-020-07519-4 · Cited by 16
Multiple transcription factors mediating the expressional regulation of myosin heavy chain gene involved in the indeterminate muscle growth of fish
Ahammad, A. K. S., Asaduzzaman, M., Ceyhun, S. B., Ceylan, H., Asakawa, S., Watabe, S., & Kinoshita, S. (2018) · Gene · doi:10.1016/j.gene.2018.11.040 · Cited by 15
Clinical screening and identification of sarcopenic obesity in adults with advanced knee osteoarthritis
Godziuk, K., Woodhouse, L. J., Prado, C. M. M., & Forhan, M. A. (2020) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2020.08.005 · Cited by 16
Associations between inflammatory markers and muscle strength in older adults according to the presence or absence of obesity
Ribeiro, J. C., Duarte, J. G., Gomes, G. A. O., Costa-Guarisco, L. P., de Jesus, I. T. M., Nascimento, C. M. C., dos Santos‐Orlandi, A. A., Orlandi, F. D. S., Vasilceac, F. A., Zazzetta, M. S., et al. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111409 · Cited by 15
Peak Power Output Is Similarly Recovered After Three- and Five-Days’ Rest Following Sprint Interval Training in Young and Older Adults
Yasar, Z., Dewhurst, S., & Hayes, L. D. (2019) · Sports · doi:10.3390/sports7040094 · Cited by 16
The Relationship between Physical Activity and Depressive Symptoms in Middle-Aged and Elderly People Controlling for Demographic and Health Status Variables
Zhang, Y., & Tian, Y. (2022) · Sustainability · doi:10.3390/su142113986 · Cited by 14
Muscle strength rather than appendicular skeletal muscle mass might affect spinal sagittal alignment, low back pain, and health-related quality of life
Tanaka, Y., Miyagi, M., Inoue, G., Hori, Y., Inage, K., Murata, K., Fujimaki, H., Kuroda, A., Yokozeki, Y., Inoue, S., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-37125-w · Cited by 14
Definition and evolution of the concept of sarcopenia
Tocino, M. L. S., Guldris, S. C., Ureña, P., González‐Casaus, M. L., Mas, S., Gracia-Iguacel, C., Ortiz, A., & González‐Parra, E. (2024) · Nefrología (English Edition) · doi:10.1016/j.nefroe.2023.08.007 · Cited by 21
Assessing muscle quality as a key predictor to differentiate fallers from non-fallers in older adults
Michel, É., Zory, R., Guérin, O., Prate, F., Sacco, G., & Chorin, F. (2024) · European Geriatric Medicine · doi:10.1007/s41999-024-01020-y · Cited by 19
Do we know about dynapenia?
Sivritepe, R. (2024) · Northern Clinics of Istanbul · doi:10.14744/nci.2024.48642 · Cited by 18
The effect of increase in baggage weight on elderly women's lower extremity muscle activation during gait
Kim, S.-G., Nam, C.-W., & Yong, M.-S. (2014) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2014.07.015 · Cited by 14
A reference equation for normal standards for knee extensor isokinetic strength in Brazilian older women
Pereira, J. C., Neri, S. G. R., Vainshelboim, B., Gadelha, A. B., Bottaro, M., & Lima, R. M. (2018) · Aging Clinical and Experimental Research · doi:10.1007/s40520-018-1084-9 · Cited by 13
Metabolic Basis and Pathogenesis of Skeletal Muscle Dysfunction as Cause of Frailty in Chronic Kidney Disease
Wesson, D. E., Mathur, V. S., & Tangri, N. (2022) · American Journal of Nephrology · doi:10.1159/000526679 · Cited by 14
Effectiveness of exercise interventions on physical function in community-dwelling frail older people
Jadczak, A. D., Makwana, N. R., Luscombe‐Marsh, N. D., Visvanathan, R., & Schultz, T. (2016) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2016-003081 · Cited by 13
Independent and combined associations of cardiorespiratory fitness and muscle strength with metabolic syndrome in older adults: A cross-sectional study
Câmara, M., Browne, R. A. V., Souto, G. C., Schwade, D., Cabral, L. L. P., Macêdo, G. A. D., Farias-Junior, L. F., Gouveia, F. L., Lemos, T. M. A. M., de Lima, K. C., et al. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.110923 · Cited by 11
Novel Essential Amino Acid Supplements Following Resistance Exercise Induce Aminoacidemia and Enhance Anabolic Signaling Irrespective of Age: A Proof-of-Concept Trial
Lees, M. J., Wilson, O. J., Webb, E. K., Traylor, D. A., Prior, T., Elia, A., Harlow, P., Black, A. D., Parker, P. J., Harris, N. J., et al. (2020) · Nutrients · doi:10.3390/nu12072067 · Cited by 15
Differences in muscle adaptation to a 12-week mixed power training in elderly men, depending on usual protein intake
Dulac, M., Pion, C. H., Lemieux, F. C., Hajj, G. B. E., Bélanger, M., Gaudreau, P., Chevalier, S., Morais, J. A., Gouspillou, G., & Aubertin‐Leheudre, M. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.02.001 · Cited by 13
Pontos de corte alternativos para massa muscular apendicular para verificação da sarcopenia em idosos brasileiros: dados da Rede Fibra - Belo Horizonte/Brasil
Viana, J. U., Dias, J. M. D., Pereira, L. S. M., da Silva, S. L. A., Hoelzle, L. F., & Dias, R. C. (2018) · Fisioterapia e Pesquisa · doi:10.1590/1809-2950/17533725022018 · Cited by 13
Risk factors for 5-year mortality in a cohort of elderly patients with sarcopenia
Abbas, H. A., Perna, S., Shah, A., Al-Mannai, M. A., Gasparri, C., Infantino, V., Cereda, E., Peroni, G., Riva, A., Petrangolini, G., et al. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.110944 · Cited by 12
Increased Leg Strength After Concurrent Aerobic and Resistance Exercise Training in Older Adults Is Augmented by a Whole Food-Based High Protein Diet Intervention
Timmons, J. F., Hone, M., Cogan, K. E., Duffy, O., & Egan, B. (2021) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2021.653962 · Cited by 11

Authors: Clark, B. C., & Manini, T. M.
Affiliations: Ohio University (US)
University of Florida (US)
Corresponding author: Manini, Todd M
ORCID: Clark, Brian C
Manini, Todd M
Venue: Current Opinion in Clinical Nutrition and Metabolic Care
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2010-05
Volume: 13
Issue: 3
Pages: 271-276
ISSN: 1363-1950 (ISSN-L)
DOI: 10.1097/mco.0b013e328337819e
PMC: PMC2895460
OpenAlex: W2064516207
Cited by: 359
References: 53
Citations by year: 2026: 8 · 2025: 11 · 2024: 23 · 2023: 21 · 2022: 24 · 2021: 37 · 2020: 30 · 2019: 15 · 2018: 24 · 2017: 29 · 2016: 25 · 2015: 34 · 2014: 22 · 2013: 21 · 2012: 19
FWCI: 1.70
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Current Opinion in Clinical Nutrition & Metabolic Care (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Aging (R21AG031974, P30AG028740)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R15HD065552)
Topics: Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
Keywords: sarcopenia, dynapenia, muscle weakness, muscle atrophy, aging, physical function, physical disability, mortality, economic burden, muscle strength, neuromuscular function, neuronal activation, muscle mass, older adults
MeSH terms: Activities of Daily Living, Aged, Persons with Disabilities, Humans, Muscle, Skeletal, Muscle Weakness, Sarcopenia

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Functional consequences of sarcopenia and dynapenia in the elderly

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks