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Cited by 53Endometriosis Research and TreatmentMenstrual Health and DisordersEctopic Pregnancy Diagnosis and Management

Length of Menstrual Cycle and Risk of Endometriosis: A Meta-Analysis of 11 Case–Control Studies

Open access
Wei, Ming, Cheng, Yanfei, Bu, Huaien, Zhao, Ye, Zhao, Wenli·2016·Medicine
DOI 10.1097/md.0000000000002922PMC PMC4782879
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Abstract

Endometriosis is a complex disease that affects a large number of women worldwide and may cause pain and infertility. To systematically review published studies evaluating the relationship between menstrual cycle length and risk of endometriosis. We searched the Cochrane Library, PubMed, Web of Science, and EMBASE in databases in July 2014 using the keywords "case-control studies," "epidemiologic determinants," "risk factors," "menstrual cycle," "menstrual length," "menstrual character," and "endometriosis." We included case-control studies published in English that investigated cases of surgically confirmed endometriosis and examined the relationship between endometriosis risk and menstrual cycle. Eleven articles that met the inclusion criteria included data of 3392 women with endometriosis and 5006 controls. Fixed-effects and random-effects models were used for the evaluation. For the association of risk of endometriosis and menstrual cycle length shorter than or equal to 27 days (SEQ27) or length longer than or equal to 29 days (LEQ29), the odds ratio was 1.22 (95% confidence interval [CI]: 1.05-1.43) and 0.68 (95% CI: 0.48-0.96), respectively. In conclusion, this meta-analysis suggests that menstrual cycle length SEQ27 increase the risk of endometriosis and cycle length LEQ29 decrease the risk.

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  • Women with endometriosis demonstrate shorter menstrual cycles relative to unaffected women.

    “Women with endometriosis, by contrast, demonstrate shorter menstrual cycles relative to unaffected women (Arumugam & Lim, 1997; Wei et al., 2016; Yasui et al., 2015).”

    From Endometriosis and polycystic ovary syndrome are diametric disorders (2021) · cites this paper as Wei et al., 2016

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Research works printed but not linked: 33

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Cited by

Sorted by citations

Authors
Wei, M., Cheng, Y., Bu, H., Zhao, Y., & Zhao, W.
Affiliations
Tianjin University of Traditional Chinese Medicine (CN)
Corresponding author
  • Zhao, Ye
  • Zhao, Wenli
ORCID
Venue
Medicine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2016-03
Volume
95
Issue
9
Pages
e2922
ISSN
0025-7974 (ISSN-L)
DOI
10.1097/md.0000000000002922
PMC
PMC4782879
OpenAlex
W2292913502
Cited by
53
References
4
Citations by year
2026: 7 · 2025: 5 · 2024: 4 · 2023: 8 · 2022: 7 · 2021: 6 · 2020: 5 · 2019: 3 · 2018: 6 · 2017: 1 · 2016: 1
FWCI
0.53
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Medicine (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Menstrual Health and Disorders
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
Keywords
endometriosis, menstrual cycle length, endometriosis risk factors, menstrual characteristics, infertility, dysmenorrhea
MeSH terms
Endometriosis, Female, Humans, Menstrual Cycle, Risk Factors, Case-Control Studies

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