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Cited by 4Reproductive Health and TechnologiesOvarian function and disordersObesity, Physical Activity, Diet

Associations between weight-adjusted-waist index and infertility: Results from NHANES 2013 to 2020

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Zhong, Huanxin, Yu, Bin, Zhao, Fen, Cui, Hongyin, You, Lifang, Feng, Dao, Lu, Yi·2023·Medicine
DOI 10.1097/md.0000000000036388PMC PMC10695495
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Abstract

Female infertility is a significant problem for women of reproductive age worldwide. Obesity has been proven to pose a danger for infertility in women. Weight-adjusted waist circumference index (WWI) is a recently created biomarker of obesity, and this research aims to explore the relationship between female infertility and WWI. Data for this investigation were gathered from National Health and Nutrition Examination Survey. We used weighted multivariate logistic regression, subgroup analysis, interaction testing, and smoothed curve fitting to investigate the relationship between infertility and WWI. A total of 6333 women were included and 708 (11.18%) had infertility. It was discovered that women with higher WWI had increased probabilities of infertility (OR = 1.92, 95% CI: 1.42–2.59) adjusting for confounders. In addition, WWI was linked to increased chances of infertility in women aged 28 to 36 years (OR = 1.59, 95% CI: 1.28–1.97). According to the results of this cross-sectional survey, WWI is positively associated with infertility among adult females in the U.S. And it can help identify infertile women and may help reduce the risk of infertility.

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Authors
Zhong, H., Yu, B., Zhao, F., Cui, H., You, L., Feng, D., & Lu, Y.
Affiliations
  • Second Affiliated Hospital of Zhejiang University (CN)
  • Gynecology Department, Linping Campus, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
Corresponding author
Zhong, Huanxin
ORCID
Venue
Medicine
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2023-12-01
Volume
102
Issue
48
Pages
e36388
ISSN
  • 0025-7974 (ISSN-L)
  • 1536-5964
DOI
10.1097/md.0000000000036388
PMC
PMC10695495
OpenAlex
W4389257675
Cited by
4
References
4
Citations by year
2026: 2 · 2025: 1 · 2024: 1
FWCI
0.96
Type
journal article
Language
en
Open access
Licence
Locations
  • Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
female infertility, weight-adjusted waist index, obesity, waist circumference, obesity biomarkers, women of reproductive age, NHANES
MeSH terms
Adult, Cross-Sectional Studies, Female, Humans, Infertility, Female, Nutrition Surveys, Obesity, Waist Circumference

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