The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.
The interaction between thyroid and kidney disease: an overview of the evidence.
Open accessAbstract
PURPOSE OF REVIEW: Hypothyroidism is highly prevalent in chronic kidney disease (CKD) patients, including those receiving dialysis. This review examines potential mechanistic links between thyroid and kidney disease; current evidence for hypothyroidism as a risk factor for de novo CKD and CKD progression; and studies of thyroid functional disorders, cardiovascular disease, and death in the CKD population. RECENT FINDINGS: Epidemiologic data have demonstrated an incrementally higher prevalence of hypothyroidism with increasing severity of kidney dysfunction. Various thyroid functional test abnormalities are also commonly observed in CKD due to alterations in thyroid hormone synthesis, metabolism, and regulation. Although the mechanistic link between thyroid and kidney disease remains unclear, observational studies suggest that hypothyroidism is associated with abnormal kidney structure and function. Previously thought to be a physiologic adaptation, recent studies show that hypothyroidism is associated with higher risk of cardiovascular disease and death in CKD. SUMMARY: A growing body of evidence suggests that hypothyroidism is a risk factor for incident CKD, CKD progression, and higher death risk in kidney disease patients. Rigorous studies are needed to determine the impact of thyroid hormone replacement upon kidney disease progression, cardiovascular disease, and mortality, which may shed light onto the causal implications of hypothyroidism in CKD.
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Cites
Thyroid hormone and the cardiovascular system.
Klein, I., & Ojamaa, K. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102153440707 · Cited by 2,300
Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.1.0455 · Cited by 1,853
Subclinical Hypothyroidism and the Risk of Coronary Heart Disease and Mortality
Rodondi, N., den Elzen, W. P. J., Bauer, D. C., Cappola, A. R., Razvi, S., Walsh, J. P., Åsvold, B. O., Iervasi, G., Imaizumi, M., Collet, T.-H., et al. (2010) · JAMA · doi:10.1001/jama.2010.1361 · Cited by 1,216
Use of Transesophageal Echocardiography to Guide Cardioversion in Patients with Atrial Fibrillation
Klein, A. L., Grimm, R. A., Murray, R. D., Apperson-Hansen, C., ASINGER, R. W., Black, I. W., Davidoff, R., Erbel, R., Halperin, J. L., Orsinelli, D. A., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105103441901 · Cited by 952
Lo, J. C.-M., Chertow, G. M., Go, A. S., & Hsu, C. (2005) · Kidney International · doi:10.1111/j.1523-1755.2005.00169.x · Cited by 372
Interactions between thyroid disorders and kidney disease
Basu, G., & Mohapatra, A. (2012) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.93737 · Cited by 326
Thyroid Hormone Metabolism and Thyroid Diseases in Chronic Renal Failure
Kaptein, E. M. (1996) · Endocrine Reviews · doi:10.1210/edrv-17-1-45 · Cited by 294
The Renal Manifestations of Thyroid Disease
Mariani, L. H., & Berns, J. S. (2011) · Journal of the American Society of Nephrology · doi:10.1681/asn.2010070766 · Cited by 291
Vascular and renal function in experimental thyroid disorders
Vargas, F., Moreno, J. M., Rodríguez‐Gómez, I., Wangensteen, R., Osuna, A., Álvarez-Guerra, M., & García‐Estañ, J. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02093 · Cited by 285
Prevalence of Subclinical Hypothyroidism in Patients with Chronic Kidney Disease
Chonchol, M., Lippi, G., Salvagno, G. L., Zoppini, G., Muggeo, M., & Targher, G. (2008) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.00800208 · Cited by 266
Research works printed but not linked: 1
- Soldin, 2013, Measuring serum thyroid-stimulating hormone, thyroid hormones, thyroid-directed antibodies, and transport proteins, Werner and Ingbar's the thyroid, 279
Cited by
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Blake, B. E., & Fenton, S. E. (2020) · Toxicology · doi:10.1016/j.tox.2020.152565 · Cited by 499
Chaker, L., Razvi, S., Bensenor, I. M., Azizi, F., Pearce, E. N., & Peeters, R. P. (2022) · Nature Reviews Disease Primers · doi:10.1038/s41572-022-00357-7 · Cited by 330
The Interplay Between Thyroid Dysfunction and Kidney Disease
Narasaki, Y., Sohn, P., & Rhee, C. M. (2021) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2021.03.008 · Cited by 84
Self-citationDiabetic Nephropathy: Novel Molecular Mechanisms and Therapeutic Targets
Zoja, C., Xinaris, C., & Macconi, D. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.586892 · Cited by 83
Sohn, S. Y., Inoue, K., Rhee, C. M., & Leung, A. M. (2024) · Endocrine Reviews · doi:10.1210/endrev/bnae019 · Cited by 72
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Metadata
- Authors
- Rhee, C. M.
- Affiliations
- University of California, Irvine (US)
- Corresponding author
- Rhee, Connie M.
- ORCID
- Rhee, Connie M.
- Venue
- Current Opinion in Endocrinology, Diabetes & Obesity
- Published
- 2016-10
- Volume
- 23
- Issue
- 5
- Pages
- 407-415
- ISSN
- 1752-296X (ISSN-L)
- 1752-2978
- PMC
- PMC5094898
- OpenAlex
- W2473748378
- Cited by
- 135
- References
- 80
- Citations by year
- 2026: 14 · 2025: 14 · 2024: 15 · 2023: 19 · 2022: 16 · 2021: 20 · 2020: 21 · 2019: 8 · 2018: 7 · 2017: 1
- FWCI
- 0.78
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Current Opinion in Endocrinology Diabetes and Obesity (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (K23DK102903)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
- Keywords
- hypothyroidism, chronic kidney disease, dialysis, chronic kidney disease progression, cardiovascular disease, mortality, thyroid hormone metabolism, thyroid hormone replacement, thyroid dysfunction
- MeSH terms
- Humans, Hypothyroidism, Renal Insufficiency, Chronic
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