Mammalian target of rapamycin complex 1 and FoxO1 in the transcriptional control of lipolysis and de novo lipogenesis

mTOR Signaling in Growth, Metabolism, and Disease

Saxton, R. A., & Sabatini, D. M. (2017) · Cell · doi:10.1016/j.cell.2017.02.004 · Cited by 7,555 · see citing works

Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

Watterson, K. R., Bestow, D., Gallagher, J. R., Hamilton, D. L., Ashford, F. B., Meakin, P. J., & Ashford, M. L. J. (2012) · Neurosignals · doi:10.1159/000334144 · Cited by 3,395 · see citing works

Critical nodes in signalling pathways: insights into insulin action

Taniguchi, C. M., Emanuelli, B., & Kahn, C. R. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1837 · Cited by 2,760 · see citing works

Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase

Zimmermann, R., Bogner‐Strauß, J. G., Haemmerle, G., Schoiswohl, G., Birner‐Gruenberger, R., Riederer, M., Lass, A., Neuberger, G., Eisenhaber, F., Hermetter, A., et al. (2004) · Science · doi:10.1126/science.1100747 · Cited by 2,121 · see citing works

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

Düvel, K., Yecies, J. L., Menon, S., Raman, P., Lipovsky, A. I., Souza, A. L., Triantafellow, E., Ma, Q., Gorski, R., Cleaver, S., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.06.022 · Cited by 2,020 · see citing works

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

Um, S. H., Frigerio, F., Watanabe, M., Picard, F., Joaquin, M., Sticker, M., Fumagalli, S., Allegrini, P. R., Kozma, S. C., Auwerx, J., et al. (2004) · Nature · doi:10.1038/nature02866 · Cited by 1,677 · see citing works

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

Porstmann, T., Santos, C. R., Griffiths, B., Cully, M., Wu, M., Leevers, S., Griffiths, J. R., Chung, Y.-L., & Schulze, A. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.07.007 · Cited by 1,413 · see citing works

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

Haemmerle, G., Lass, A., Zimmermann, R., Gorkiewicz, G., Meyer, C., Rozman, J., Heldmaier, G., Maier, R., Theussl, C., Eder, S., et al. (2006) · Science · doi:10.1126/science.1123965 · Cited by 1,375 · see citing works

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

Peterson, T. R., Sengupta, S., Harris, T. E., Carmack, A. E., Kang, S. A. W., Balderas, E., Guertin, D. A., Madden, K. L., Carpenter, A. E., Finck, B. N., et al. (2011) · Cell · doi:10.1016/j.cell.2011.06.034 · Cited by 1,233 · see citing works

The mTOR‐regulated phosphoproteome reveals a mechanism of mTORC1‐mediated inhibition of growth factor signaling

Hsu, P. P., Kang, S. A., Rameseder, J., Zhang, Y., Ottina, K. A., Lim, D., Peterson, T. R., Choi, Y., Gray, N. S., Yaffe, M. B., et al. (2011) · Science · doi:10.1126/science.1199498 · Cited by 1,084 · see citing works

Regulation of Lipolysis in Adipocytes

Duncan, R. E., Ahmadian, M., Jaworski, K., Sarkadi-Nagy, E., & Sul, H. S. (2007) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.27.061406.093734 · Cited by 1,021 · see citing works

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

Yu, Y., Yoon, S.-O., Poulogiannis, G., Yang, Q., Ma, X. M., Villén, J., Kubica, N., Hoffman, G. R., Cantley, L. C., Gygi, S. P., et al. (2011) · Science · doi:10.1126/science.1199484 · Cited by 855 · see citing works

Lipolysis and lipid mobilization in human adipose tissue

Lafontan, M., & Langin, D. (2009) · Progress in Lipid Research · doi:10.1016/j.plipres.2009.05.001 · Cited by 825 · see citing works

Inappropriate Activation of the TSC/Rheb/mTOR/S6K Cassette Induces IRS1/2 Depletion, Insulin Resistance, and Cell Survival Deficiencies

Shah, O. J., Wang, Z., & Hunter, T. R. (2004) · Current Biology · doi:10.1016/j.cub.2004.08.026 · Cited by 800 · see citing works

Identification, Cloning, Expression, and Purification of Three Novel Human Calcium-independent Phospholipase A2 Family Members Possessing Triacylglycerol Lipase and Acylglycerol Transacylase Activities

Jenkins, C. M., Mancuso, D. J., Yan, W., Sims, H. F., Gibson, B., & Gross, R. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407841200 · Cited by 778 · see citing works

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

Li, S., Brown, M. S., & Goldstein, J. L. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914798107 · Cited by 733 · see citing works

The Forkhead Transcription Factor Foxo1 Regulates Adipocyte Differentiation

Nakae, J., Kitamura, T., Kitamura, Y., Biggs, W., Arden, K. C., & Accili, D. (2003) · Developmental Cell · doi:10.1016/s1534-5807(02)00401-x · Cited by 727 · see citing works

Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways

Yecies, J. L., Zhang, H., Menon, S., Liu, S., Yecies, D. W., Lipovsky, A. I., Görgün, C. Z., Kwiatkowski, D. J., Hotamışlıgil, G. S., Lee, C., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.06.002 · Cited by 655 · see citing works

Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila

Grönke, S., Mildner, A., Fellert, S., Tennagels, N., Petry, S., Müller, G. A., Jäckle, H., & Kühnlein, R. P. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.04.003 · Cited by 621 · see citing works

Transcriptional Control of Adipose Lipid Handling by IRF4

Eguchi, J., Wang, X., Yu, S., Kershaw, E. E., Chiu, P. C., Dushay, J. R., Estall, J. L., Klein, U., Maratos–Flier, E., & Rosen, E. D. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.02.005 · Cited by 607 · see citing works

Desnutrin, an Adipocyte Gene Encoding a Novel Patatin Domain-containing Protein, Is Induced by Fasting and Glucocorticoids

Villena, J. A., Roy, S., Sarkadi‐Nagy, E., Kim, K., & Sul, H. S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403855200 · Cited by 606 · see citing works

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores.

Zechner, R., Kienesberger, P. C., Haemmerle, G., Zimmermann, R., & Lass, A. (2009) · Journal of Lipid Research · doi:10.1194/jlr.r800031-jlr200 · Cited by 576 · see citing works

The role of FoxO in the regulation of metabolism

Gross, D. N., van den Heuvel, A. P. J., & Birnbaum, M. J. (2008) · Oncogene · doi:10.1038/onc.2008.25 · Cited by 555 · see citing works

Expanding Roles for SREBP in Metabolism

Shao, W., & Espenshade, P. J. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.09.002 · Cited by 518 · see citing works

FoxO1 Regulates Multiple Metabolic Pathways in the Liver

Zhang, W., Patil, S., Chauhan, B., Guo, S., Powell, D. R., Le, J., Klotsas, A., Matika, R. W., Xiao, X., Franks, R. R., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600272200 · Cited by 517 · see citing works

Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration

Polak, P., Cybulski, N., Feige, J. N., Auwerx, J., Rüegg, M. A., & Hall, M. N. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.09.003 · Cited by 480 · see citing works

Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue

Houde, V. P., Brûlé, S., Festuccia, W. T., Blanchard, P.-G., Bellmann, K., Deshaies, Y., & Marette, A. (2010) · Diabetes · doi:10.2337/db09-1324 · Cited by 456 · see citing works

Regulation of Peroxisome Proliferator–Activated Receptor-γ Activity by Mammalian Target of Rapamycin and Amino Acids in Adipogenesis

Kim, J. E., & Chen, J. (2004) · Diabetes · doi:10.2337/diabetes.53.11.2748 · Cited by 454 · see citing works

Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

Matsumoto, M. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27047 · Cited by 430 · see citing works

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

Tzatsos, A., & Kandror, K. V. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.1.63-76.2006 · Cited by 399 · see citing works

Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway

Zhang, H., Huang, J., Düvel, K., Boback, B. B., Wu, S., Squillace, R. M., Wu, C., & Manning, B. D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006189 · Cited by 393 · see citing works

Adipose Triglyceride Lipase: Function, Regulation by Insulin, and Comparison With Adiponutrin

Kershaw, E. E. (2006) · Diabetes · doi:10.2337/diabetes.55.1.148 · Cited by 386 · see citing works

Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

Nielsen, T. S., Jessen, N., Jørgensen, J. O. L., Møller, N., & Lund, S. A. (2014) · Journal of Molecular Endocrinology · doi:10.1530/jme-13-0277 · Cited by 380 · see citing works

Insulin-Induced Phosphorylation and Activation of Cyclic Nucleotide Phosphodiesterase 3B by the Serine-Threonine Kinase Akt

Kitamura, T., Kitamura, Y., Kuroda, S., Hino, Y., Ando, M., Kotani, K., Konishi, H., Matsuzaki, H., Kikkawa, U., Ogawa, W., et al. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6286 · Cited by 371 · see citing works

FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor

Chen, C.-C., Jeon, S., Bhaskar, P. T., Nogueira, V., Sundararajan, D., Tonic, I., Park, Y., & Hay, N. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.03.008 · Cited by 369 · see citing works

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.

Bacquer, O. L., Petroulakis, E., Paglialunga, S., Poulin, F., Richard, D., Cianflone, K., & Sonenberg, N. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29528 · Cited by 365 · see citing works

ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells

Smirnova, E., Goldberg, E. B., Makarova, K. S., Lin, L., Brown, W. J., & Jackson, C. L. (2005) · EMBO Reports · doi:10.1038/sj.embor.7400559 · Cited by 338 · see citing works

Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis, and Signaling

Coleman, R., & Mashek, D. G. (2011) · Chemical Reviews · doi:10.1021/cr100404w · Cited by 332 · see citing works

Obese Yeast: Triglyceride Lipolysis Is Functionally Conserved from Mammals to Yeast

Kurat, C. F., Natter, K., Petschnigg, J., Wolinski, H., Scheuringer, K., Scholz, H., Zimmermann, R., Leber, R., Zechner, R., & Kohlwein, S. D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508414200 · Cited by 323 · see citing works

The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1

Han, J., Li, E., Chen, L., Zhang, Y., Wei, F., Liu, J., Deng, H., & Wang, Y. (2015) · Nature · doi:10.1038/nature14557 · Cited by 312 · see citing works

Renal angiomyolipomata

Bissler, J. J., & Kingswood, J. C. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00838.x · Cited by 306 · see citing works

Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production

Titchenell, P. M., Quinn, W. J., Lu, M., Chu, Q., Lu, W., Li, C., Chen, H., Monks, B. R., Chen, J., Rabinowitz, J. D., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.04.022 · Cited by 281 · see citing works

Insulin signalling mechanisms for triacylglycerol storage

Czech, M., Tencerová, M., Pedersen, D. J., & Aouadi, M. (2013) · Diabetologia · doi:10.1007/s00125-013-2869-1 · Cited by 272 · see citing works

Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage

Chakrabarti, P., English, T., Shi, J., Smas, C. M., & Kandror, K. V. (2010) · Diabetes · doi:10.2337/db09-1602 · Cited by 228 · see citing works

Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells.

Yeh, W., Bierer, B. E., & McKnight, S. L. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.24.11086 · Cited by 226 · see citing works

FoxO1 Controls Insulin-dependent Adipose Triglyceride Lipase (ATGL) Expression and Lipolysis in Adipocytes*

Chakrabarti, P., & Kandror, K. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.c800241200 · Cited by 226 · see citing works

Translational regulation mechanisms of AP-1 proteins

Vesely, P. W., Staber, P. B., Höefler, G., & Kenner, L. (2009) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2009.01.001 · Cited by 222 · see citing works

Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Lipolysis in hMADS Adipocytes

Bézaire, V., Mairal, A., Ribet, C., Lefort, C., Girousse, A., Jocken, J. W. E., Laurencikiene, J., Anesia, R., Rodriguez, A., Rydén, M., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.008631 · Cited by 219 · see citing works

Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway

Choi, S. M., Tucker, D. F., Gross, D. N., Easton, R., DiPilato, L. M., Dean, A. S., Monks, B. R., & Birnbaum, M. J. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00797-10 · Cited by 211 · see citing works

S6K1 Plays a Critical Role in Early Adipocyte Differentiation

Carnevalli, L. S., Masuda, K., Frigerio, F., Bacquer, O. L., Um, S. H., Gandin, V., Topisirović, I., Sonenberg, N., Thomas, G., & Kozma, S. C. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.02.018 · Cited by 205 · see citing works

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors

Haeusler, R. A., Hartil, K., Vaitheesvaran, B., Arrieta‐Cruz, I., Knight, C. M., Cook, J. R., Kammoun, H. L., Febbraio, M. A., Juárez, R. G., Kurland, I. J., et al. (2014) · Nature Communications · doi:10.1038/ncomms6190 · Cited by 192 · see citing works

Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway

West, M. J., Stoneley, M., & Willis, A. E. (1998) · Oncogene · doi:10.1038/sj.onc.1201990 · Cited by 183 · see citing works

Insulin Inhibits Lipolysis in Adipocytes via the Evolutionarily Conserved mTORC1-Egr1-ATGL-Mediated Pathway

Chakrabarti, P., Kim, J. Y., Singh, M., Shin, Y., Kim, J., Kumbrink, J., Wu, Y., Lee, M., Kirsch, K. H., Fried, S. K., et al. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01584-12 · Cited by 176 · see citing works

Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity

Luong, N., Davies, C. R., Wessells, R. J., Graham, S. M., King, M. T., Veech, R. L., Bodmer, R., & Oldham, S. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.05.013 · Cited by 171 · see citing works

Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes

Miyoshi, H., Perfield, J. W., Obin, M. S., & Greenberg, A. S. (2008) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21964 · Cited by 169 · see citing works

Insulin signaling to hepatic lipid metabolism in health and disease

Leavens, K. F., & Birnbaum, M. J. (2011) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2011.562481 · Cited by 162 · see citing works

FoxO1 Inhibits Sterol Regulatory Element-binding Protein-1c (SREBP-1c) Gene Expression via Transcription Factors Sp1 and SREBP-1c

Deng, X., Zhang, W., O‐Sullivan, I., Williams, J. B., Dong, Q., Park, E. A., Raghow, R., Unterman, T. G., & Elam, M. B. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.347211 · Cited by 147 · see citing works

Postprandial Hepatic Lipid Metabolism Requires Signaling though Akt2 Independent of the Transcription Factors FoxA2, FoxO1 and SREBP1c

Wan, M., Leavens, K. F., Saleh, D., Easton, R., Guertin, D., Peterson, T. R., Kaestner, K., Sabatini, D., & Birnbaum, M. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.09.001 · Cited by 138 · see citing works

EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice

Arif, A., Terenzi, F., Potdar, A. A., Jia, J., Sacks, J., China, A., Halawani, D., Vasu, K. I., Li, X., Brown, J. M., et al. (2017) · Nature · doi:10.1038/nature21380 · Cited by 129 · see citing works

Grb10 Promotes Lipolysis and Thermogenesis by Phosphorylation-Dependent Feedback Inhibition of mTORC1

Liu, M., Bai, J., He, S., Villarreal, R., Hu, D., Zhang, C., Yang, X., Liang, H., Slaga, T. J., Yu, Y., et al. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2014.03.018 · Cited by 122 · see citing works

Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease

Lee, P. L., Tang, Y., Li, H., & Guertin, D. A. (2016) · Molecular Metabolism · doi:10.1016/j.molmet.2016.04.001 · Cited by 115 · see citing works

DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

Laplante, M., Horvat, S., Festuccia, W. T., Birsoy, K., Prevoršek, Z., Efeyan, A., & Sabatini, D. M. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.07.008 · Cited by 114 · see citing works

Drosophila Melted Modulates FOXO and TOR Activity

Teleman, A. A., Chen, Y., & Cohen, S. M. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.07.004 · Cited by 113 · see citing works

Transcriptional regulation of the stress response by mTOR

Aramburu, J. F., Ortells, M. C., Vaquero, S. T., Buxadé, M., & López‐Rodríguez, C. (2014) · Science Signaling · doi:10.1126/scisignal.2005326 · Cited by 98 · see citing works

The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation

Boyle, K. B., Hadaschik, D., Virtue, S., Cawthorn, W. P., Ridley, S. H., O’Rahilly, S., & Siddle, K. (2009) · Cell Death and Differentiation · doi:10.1038/cdd.2009.11 · Cited by 96 · see citing works

20-Hydroxyecdysone-induced transcriptional activity of FoxO upregulates brummer and acid lipase-1 and promotes lipolysis in Bombyx fat body

Hossain, M. S., Liu, Y., Zhou, S., Li, K., Tian, L., & Li, S. (2013) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2013.06.007 · Cited by 95 · see citing works

Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins

Zhang, W., Bu, S. Y., Mashek, M. T., O‐Sullivan, I., Sibai, Z., Khan, S. A., Ilkayeva, O., Newgard, C. B., Mashek, D. G., & Unterman, T. G. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.03.021 · Cited by 80 · see citing works

Hepatic FoxO1 Integrates Glucose Utilization and Lipid Synthesis through Regulation of Chrebp O-Glycosylation

Ido-Kitamura, Y., Sasaki, T., Kobayashi, M., Kim, H., Lee, Y., Kikuchi, O., Yokota‐Hashimoto, H., Iizuka, K., Accili, D., & Kitamura, T. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047231 · Cited by 75 · see citing works

Rheb Is Essential for Murine Development

Goorden, S. M. I., Hoogeveen‐Westerveld, M., Cheng, C., van Woerden, G. M., Mozaffari, M., Post, L. C., Duckers, H. J., Nellist, M. D., & Elgersma, Y. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.00985-10 · Cited by 75 · see citing works

KSRP and MicroRNA 145 Are Negative Regulators of Lipolysis in White Adipose Tissue

Lin, Y.-Y., Chou, C., Giovarelli, M., et al. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.00042-14 · Cited by 72 · see citing works

Tuberous Sclerosis Complex-1 Deficiency Attenuates Diet-Induced Hepatic Lipid Accumulation

Kenerson, H. L., Yeh, M. M., & Yeung, R. S. W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018075 · Cited by 70 · see citing works

mTORC1 Inhibition via Rapamycin Promotes Triacylglycerol Lipolysis and Release of Free Fatty Acids in 3T3‐L1 Adipocytes

Soliman, G. A., Acosta-Jaquez, H. A., & Fingar, D. C. (2010) · Lipids · doi:10.1007/s11745-010-3488-y · Cited by 69 · see citing works

Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death

Kim, J. Y., Liu, K., Zhou, S., Tillison, K., Wu, Y. H., & Smas, C. M. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00104.2007 · Cited by 64 · see citing works

Early Growth Response 1 (Egr1) Regulates Cholesterol Biosynthetic Gene Expression

Gokey, N. G., Lopez-Anido, C. B., Gillian‐Daniel, A. L., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.263509 · Cited by 62 · see citing works

Fat-specific Protein 27 Inhibits Lipolysis by Facilitating the Inhibitory Effect of Transcription Factor Egr1 on Transcription of Adipose Triglyceride Lipase

Singh, M., Kaur, R., Lee, M., Pickering, R. T., Sharma, V. M., Puri, V., & Kandror, K. V. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.c114.563080 · Cited by 58 · see citing works

Fatty Foci in the Myocardium in Patients with Tuberous Sclerosis Complex: Common Finding at CT

Adriaensen, M. E. A. P. M., Schaefer‐Prokop, C. M., Duyndam, D., Zonnenberg, B. A., & Prokop, M. (2009) · Radiology · doi:10.1148/radiol.2533082118 · Cited by 49 · see citing works

Mechanistic target of rapamycin controls homeostasis of adipogenesis

Yoon, M., Zhang, C., Sun, Y., Schoenherr, C. J., & Chen, J. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m037705 · Cited by 48 · see citing works

Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice

Magdalon, J., Chimin, P., Belchior, T., das Neves, R. X., Vieira‐Lara, M. A., Andrade, M. L., Farias, T. S. M., Lopes, A. B., Paschoal, V. A., Yamashita, A. S., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.02.023 · Cited by 45 · see citing works

The role of mTOR in lipid homeostasis and diabetes progression

Chakrabarti, P., & Kandror, K. V. (2015) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000187 · Cited by 43 · see citing works

Livers with Constitutive mTORC1 Activity Resist Steatosis Independent of Feedback Suppression of Akt

Kenerson, H. L., Subramanian, S., McIntyre, R. L., Kazami, M., & Yeung, R. S. W. (2015) · PLoS ONE · doi:10.1371/journal.pone.0117000 · Cited by 31 · see citing works

Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes

Ito, M., Nagasawa, M., Omae, N., Ide, T., Akasaka, Y., & Murakami, K. (2011) · Journal of Lipid Research · doi:10.1194/jlr.m012427 · Cited by 29 · see citing works

4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL

Singh, M., Shin, Y., Yang, X., Zehr, B., Chakrabarti, P., & Kandror, K. V. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.631895 · Cited by 28 · see citing works

Signaling Pathways Leading to Transcription and Translation Cooperatively Regulate the Transient Increase in Expression of c-Fos Protein

Takeuchi, K., Shibamoto, S., Nagamine, K., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102704200 · Cited by 19 · see citing works

Identification of two polymorphisms in the early growth response protein-1 gene: possible association with lipid variables

Brand, E., Herrmann, S.-M., Nicaud, V., et al. (2000) · Journal of Molecular Medicine · doi:10.1007/s001090000074 · Cited by 17 · see citing works

Beyond Calories: Individual Metabolic and Hormonal Adaptations Driving Variability in Weight Management—A State-of-the-Art Narrative Review

Theodorakis, N., Kreouzi, M., Pappas, A., & Nikolaou, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413438 · Cited by 43 · see citing works

Effects of Age and Adenosine in the Modulation of Insulin Action on Rat Adipocyte Metabolism

Rolband, G. C., FURTH, E. D., Staddon, J. M., et al. (1990) · Journal of Gerontology · doi:10.1093/geronj/45.5.b174 · Cited by 27 · see citing works

Insulin Receptor Binding to Fat and Blood Cells and Insulin Action in Fat Cells from Insulin-dependent Diabetics

Pedersen, O. B., & Hjøllund, E. (1982) · Diabetes · doi:10.2337/diab.31.8.706 · Cited by 64 · see citing works

Altered lipid metabolism in vasopressin V receptor-deficient mice

Hiroyama, M., Fujiwara, Y., Nakamura, K., Aoyagi, T., Mizutani, R., Sanbe, A., Tasaki, R., & Tanoue, A. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.11.043 · Cited by 33 · see citing works

Insulin binding and insulin action in rat fat cells after adrenalectomy

H�ring, H. U., Calle, C., Bug, A., Renner, R., Hepp, K. D., & KEMMLER, W. K. (1980) · Diabetologia · doi:10.1007/bf00280524 · Cited by 14 · see citing works

In Vitro Insulin-Like Actions of the Growth Factor from the Tapeworm, Spirometra mansonoides

Salem, M. A. M., & Phares, C. K. (1989) · Experimental Biology and Medicine · doi:10.3181/00379727-190-42851 · Cited by 7 · see citing works