The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Prediction Accuracy With Electronic Medical Records Versus Administrative Claims
Abstract
Objective: The objective of this study was to evaluate the incremental predictive power of electronic medical record (EMR) data, relative to the information available in more easily accessible and standardized insurance claims data. Data and Methods: Using both EMR and Claims data, we predicted outcomes for 118,510 patients with 144,966 hospitalizations in 8 hospitals, using widely used prediction models. We use cross-validation to prevent overfitting and tested predictive performance on separate data that were not used for model training. Main Outcomes: We predict 4 binary outcomes: length of stay (≥7 d), death during the index admission, 30-day readmission, and 1-year mortality. Results: We achieve nearly the same prediction accuracy using both EMR and claims data relative to using claims data alone in predicting 30-day readmissions [area under the receiver operating characteristic curve (AUC): 0.698 vs. 0.711; positive predictive value (PPV) at top 10% of predicted risk: 37.2% vs. 35.7%], and 1-year mortality (AUC: 0.902 vs. 0.912; PPV: 64.6% vs. 57.6%). EMR data, especially from the first 2 days of the index admission, substantially improved prediction of length of stay (AUC: 0.786 vs. 0.837; PPV: 58.9% vs. 55.5%) and inpatient mortality (AUC: 0.897 vs. 0.950; PPV: 24.3% vs. 14.0%). Results were similar for sensitivity, specificity, and negative predictive value across alternative cutoffs and for using alternative types of predictive models. Conclusion: EMR data are useful in predicting short-term outcomes. However, their incremental value for predicting longer-term outcomes is smaller. Therefore, for interventions that are based on long-term predictions, using more broadly available claims data is equally effective.
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Several FEMRs have been trained on insurance claims.
“Several FEMRs have been trained on insurance claims”
From The shaky foundations of large language models and foundation models for electronic health records (2023) · cites this paper as [63]
Insurance claims are typically larger in size and more diverse than EMR data but contain less granular information.
“which are typically larger in size and more diverse than EMR data but contain less granular information63.”
From The shaky foundations of large language models and foundation models for electronic health records (2023) · cites this paper as [63]
Citations
Cites
Scalable and accurate deep learning with electronic health records
Rajkomar, A., Oren, E., Chen, K., Dai, A. M., Hajaj, N., Hardt, M., Liu, P. J., Liu, X., Marcus, J., Sun, M., et al. (2018) · npj Digital Medicine · doi:10.1038/s41746-018-0029-1 · Cited by 2,648
The “Meaningful Use” Regulation for Electronic Health Records
Blumenthal, D., & Tavenner, M. (2010) · New England Journal of Medicine · doi:10.1056/nejmp1006114 · Cited by 2,059
Intelligible Models for HealthCare: Predicting Pneumonia Risk and Hospital 30-day Readmission
Caruana, R., Lou, Y., Gehrke, J., Koch, P., Sturm, M., & Elhadad, N. (2015) · Proceedings of the 21th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining · doi:10.1145/2783258.2788613 · Cited by 1,685
Krumholz, H. M. (2014) · Health Affairs · doi:10.1377/hlthaff.2014.0053 · Cited by 589
Tang, P. C., Ralston, M., Arrigotti, M. F., Qureshi, L., & Graham, J. (2007) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m2198 · Cited by 193 · cited 2×
“To understand the relative importance of these different types of information, we defined 4 nested sets of predictors: (1) Basic Claims; (2) Detailed Claims; (3) EMR and Claims combined, which includes data up to but excluding the index admission; and (4) EMR, Claims, and Admission, which include in addition EMR from…”
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Research works printed but not linked: 34
- Yoo, 2012, Data mining in healthcare and biomedicine: a survey of the literature, J Med Syst, 36, 2431, 10.1007/s10916-011-9710-5 · DOI
- Pencina, 2016, Moving from clinical trials to precision medicine: the role for predictive modeling, JAMA, 315, 1713, 10.1001/jama.2016.4839 · DOI
- Gulshan, 2016, Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs, JAMA, 316, 2402, 10.1001/jama.2016.17216 · DOI · Paper page
- Kim, 2017, Development of machine learning models for diagnosis of glaucoma, PLoS ONE, 12, e0177726, 10.1371/journal.pone.0177726 · DOI
- Weiss, 2012, Machine learning for personalized medicine: predicting primary myocardial infarction from electronic health records, AI Mag, 33, 33
- De Castro, 2013, Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance, Clin Pharmacol Ther, 93, 252, 10.1038/clpt.2012.237 · DOI
- Phillips, 2012, Developing targeted health service interventions using the PRECEDE-PROCEED model: two Australian case studies, Nurs Res Pract, 2012, 279431
- Bates, 2014, Big data in health care: using analytics to identify and manage high-risk and high-cost patients, Health Aff, 33, 1123, 10.1377/hlthaff.2014.0041 · DOI · Paper page
- Cai, 2015, Real-time prediction of mortality, readmission, and length of stay using electronic health record data, J Am Med Inform Assoc, 23, 553, 10.1093/jamia/ocv110 · DOI
- Choi, 2016, Doctor AI: predicting clinical events via recurrent neural networks, JMLR Workshop Conf Proc, 56, 301
- David, 2018, The effect of predictive analytics on healthcare utilization, J Health Econ, 64, 68, 10.1016/j.jhealeco.2019.02.002 · DOI
- Kansagara, 2011, Risk prediction models for hospital readmission: a systematic review, JAMA, 306, 1688, 10.1001/jama.2011.1515 · DOI
- Donzé, 2013, Potentially avoidable 30-day hospital readmissions in medical patients: derivation and validation of a prediction model, JAMA Intern Med, 173, 632, 10.1001/jamainternmed.2013.3023 · DOI · Paper page
- Betihavas, 2015, An absolute risk prediction model to determine unplanned cardiovascular readmissions for adults with chronic heart failure, Heart Lung Circ, 24, 1068, 10.1016/j.hlc.2015.04.168 · DOI
- Shadmi, 2015, Predicting 30-day readmissions with preadmission electronic health record data, Med Care, 53, 283, 10.1097/MLR.0000000000000315 · DOI
- Zhou, 2016, Utility of models to predict 28-day or 30-day unplanned hospital readmissions: an updated systematic review, BMJ Open, 6, e011060, 10.1136/bmjopen-2016-011060 · DOI
- Miller, 2014, Health information exchange, system size and information silos, J Health Econ, 33, 28, 10.1016/j.jhealeco.2013.10.004 · DOI
- Adler-Milstein, 2015, Electronic health record adoption in US hospitals: progress continues, but challenges persist, Health Aff, 34, 2174, 10.1377/hlthaff.2015.0992 · DOI · Paper page
- Goldstein, 2017, Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review, J Am Med Inform Assoc, 24, 198, 10.1093/jamia/ocw042 · DOI · Paper page
- Silva, 2006, Mortality assessment in intensive care units via adverse events using artificial neural networks, Artif Intell Med, 36, 223, 10.1016/j.artmed.2005.07.006 · DOI
- Gagne, 2011, A combined comorbidity score predicted mortality in elderly patients better than existing scores, J Clin Epidemiol, 64, 749, 10.1016/j.jclinepi.2010.10.004 · DOI · Paper page
- Tabak, 2013, Using electronic health record data to develop inpatient mortality predictive model: Acute Laboratory Risk of Mortality Score (ALaRMS), J Am Med Inform Assoc, 21, 455, 10.1136/amiajnl-2013-001790 · DOI · Paper page
- Makar, 2015, Short-term mortality prediction for elderly patients using Medicare claims data, Int J Mach Learn Comput, 5, 192, 10.7763/IJMLC.2015.V5.506 · DOI
- Awad, 2017, Early hospital mortality prediction of intensive care unit patients using an ensemble learning approach, Int J Med Inform, 108, 185, 10.1016/j.ijmedinf.2017.10.002 · DOI · Paper page
- He, 2014, Mining high-dimensional administrative claims data to predict early hospital readmissions, J Am Med Inform Assoc, 21, 272, 10.1136/amiajnl-2013-002151 · DOI
- Kharrazi, 2017, Comparing population-based risk-stratification model performance using demographic, diagnosis and medication data extracted from outpatient electronic health records versus administrative claims, Med Care, 55, 789, 10.1097/MLR.0000000000000754 · DOI
- Kharrazi, 2018, A practical comparison between the predictive power of population-based risk stratification models using data from electronic health records versus administrative claims: setting a baseline for future EHR-derived risk stratification models, Med Care, 56, 202, 10.1097/MLR.0000000000000849 · DOI
- Shadmi, 2011, Assessing socioeconomic health care utilization inequity in Israel: impact of alternative approaches to morbidity adjustment, BMC Public Health, 11, 609, 10.1186/1471-2458-11-609 · DOI
- Escobar, 2008, Risk-adjusting hospital inpatient mortality using automated inpatient, outpatient, and laboratory databases, Med Care, 46, 232, 10.1097/MLR.0b013e3181589bb6 · DOI
- Escobar, 2015, Nonelective rehospitalizations and postdischarge mortality: predictive models suitable for use in real time, Med Care, 53, 916, 10.1097/MLR.0000000000000435 · DOI
- Nguyen, 2016, Predicting all-cause readmissions using electronic health record data from the entire hospitalization: model development and comparison, J Hosp Med, 11, 473, 10.1002/jhm.2568 · DOI · Paper page
- Tonkikh, 2016, Functional status before and during acute hospitalization and readmission risk identification, J Hosp Med, 11, 636, 10.1002/jhm.2595 · DOI
- Bartkowiak, 2019, Validating the Electronic Cardiac Arrest Risk Triage (eCART) Score for risk stratification of surgical inpatients in the postoperative setting: retrospective cohort study, Ann Surg, 269, 1059, 10.1097/SLA.0000000000002665 · DOI
- Horne, 2017, Early inpatient calculation of laboratory-based 30-day readmission risk scores empowers clinical risk modification during index hospitalization, Am Heart J, 185, 101, 10.1016/j.ahj.2016.12.010 · DOI
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Sorted by citations
The shaky foundations of large language models and foundation models for electronic health records
Wornow, M., Xu, Y., Thapa, R., Patel, B., Steinberg, E., Fleming, S., Pfeffer, M. A., Fries, J., & Shah, N. H. (2023) · npj Digital Medicine · doi:10.1038/s41746-023-00879-8 · Cited by 324
“Several FEMRs have been trained on insurance claims, which are typically larger in size and more diverse than EMR data but contain less granular information 63 .”
Background
Metadata
- Authors
- Zeltzer, D., Balicer, R. D., Shir, T., Flaks-Manov, N., Einav, L., & Shadmi, E.
- Affiliations
- Tel Aviv University (IL)
- Ben-Gurion University of the Negev (IL)
- Clalit Health Services (IL)
- Clalit Health Services, Clalit Research Institute, Tel Aviv
- Department of Economics, Stanford University, Stanford, CA
- Corresponding author
- Zeltzer, Dan
- Venue
- Medical Care
- Published
- 2019-07
- Volume
- 57
- Issue
- 7
- Pages
- 551-559
- ISSN
- 0025-7079 (ISSN-L)
- OpenAlex
- W2945965960
- Cited by
- 34
- References
- 5
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 8 · 2023: 4 · 2022: 5 · 2021: 9 · 2020: 3
- FWCI
- 1.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Medical Care (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
- Health Sciences › Health Professions › Health Information Management › Medical Coding and Health Information
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Keywords
- electronic health records, health insurance claims, hospital readmission prediction, in-hospital mortality prediction, length of hospital stay, prediction accuracy, incremental predictive value, hospitalization outcomes
- MeSH terms
- Data Accuracy, Adult, Cause of Death, Female, Hospitalization, Humans, Insurance Claim Reporting, Israel, Length of Stay, Male, Middle Aged, Patient Readmission, Hospital Mortality, Electronic Health Records
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