Cited by 34Machine Learning in HealthcareMedical Coding and Health InformationElectronic Health Records Systems

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Prediction Accuracy With Electronic Medical Records Versus Administrative Claims

Zeltzer, Dan, Balicer, Ran D., Shir, Tzvi, Flaks-Manov, Natalie, Einav, Liran, Shadmi, Efrat·2019·Medical Care

Abstract

Objective: The objective of this study was to evaluate the incremental predictive power of electronic medical record (EMR) data, relative to the information available in more easily accessible and standardized insurance claims data. Data and Methods: Using both EMR and Claims data, we predicted outcomes for 118,510 patients with 144,966 hospitalizations in 8 hospitals, using widely used prediction models. We use cross-validation to prevent overfitting and tested predictive performance on separate data that were not used for model training. Main Outcomes: We predict 4 binary outcomes: length of stay (≥7 d), death during the index admission, 30-day readmission, and 1-year mortality. Results: We achieve nearly the same prediction accuracy using both EMR and claims data relative to using claims data alone in predicting 30-day readmissions [area under the receiver operating characteristic curve (AUC): 0.698 vs. 0.711; positive predictive value (PPV) at top 10% of predicted risk: 37.2% vs. 35.7%], and 1-year mortality (AUC: 0.902 vs. 0.912; PPV: 64.6% vs. 57.6%). EMR data, especially from the first 2 days of the index admission, substantially improved prediction of length of stay (AUC: 0.786 vs. 0.837; PPV: 58.9% vs. 55.5%) and inpatient mortality (AUC: 0.897 vs. 0.950; PPV: 24.3% vs. 14.0%). Results were similar for sensitivity, specificity, and negative predictive value across alternative cutoffs and for using alternative types of predictive models. Conclusion: EMR data are useful in predicting short-term outcomes. However, their incremental value for predicting longer-term outcomes is smaller. Therefore, for interventions that are based on long-term predictions, using more broadly available claims data is equally effective.

Overview

Integrity signals

Registry

Crossref · 10.1097/mlr.0000000000001135

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 34

  1. Yoo, 2012, Data mining in healthcare and biomedicine: a survey of the literature, J Med Syst, 36, 2431, 10.1007/s10916-011-9710-5 · DOI
  2. Pencina, 2016, Moving from clinical trials to precision medicine: the role for predictive modeling, JAMA, 315, 1713, 10.1001/jama.2016.4839 · DOI
  3. Gulshan, 2016, Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs, JAMA, 316, 2402, 10.1001/jama.2016.17216 · DOI · Paper page
  4. Kim, 2017, Development of machine learning models for diagnosis of glaucoma, PLoS ONE, 12, e0177726, 10.1371/journal.pone.0177726 · DOI
  5. Weiss, 2012, Machine learning for personalized medicine: predicting primary myocardial infarction from electronic health records, AI Mag, 33, 33
  6. De Castro, 2013, Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance, Clin Pharmacol Ther, 93, 252, 10.1038/clpt.2012.237 · DOI
  7. Phillips, 2012, Developing targeted health service interventions using the PRECEDE-PROCEED model: two Australian case studies, Nurs Res Pract, 2012, 279431
  8. Bates, 2014, Big data in health care: using analytics to identify and manage high-risk and high-cost patients, Health Aff, 33, 1123, 10.1377/hlthaff.2014.0041 · DOI · Paper page
  9. Cai, 2015, Real-time prediction of mortality, readmission, and length of stay using electronic health record data, J Am Med Inform Assoc, 23, 553, 10.1093/jamia/ocv110 · DOI
  10. Choi, 2016, Doctor AI: predicting clinical events via recurrent neural networks, JMLR Workshop Conf Proc, 56, 301
  11. David, 2018, The effect of predictive analytics on healthcare utilization, J Health Econ, 64, 68, 10.1016/j.jhealeco.2019.02.002 · DOI
  12. Kansagara, 2011, Risk prediction models for hospital readmission: a systematic review, JAMA, 306, 1688, 10.1001/jama.2011.1515 · DOI
  13. Donzé, 2013, Potentially avoidable 30-day hospital readmissions in medical patients: derivation and validation of a prediction model, JAMA Intern Med, 173, 632, 10.1001/jamainternmed.2013.3023 · DOI · Paper page
  14. Betihavas, 2015, An absolute risk prediction model to determine unplanned cardiovascular readmissions for adults with chronic heart failure, Heart Lung Circ, 24, 1068, 10.1016/j.hlc.2015.04.168 · DOI
  15. Shadmi, 2015, Predicting 30-day readmissions with preadmission electronic health record data, Med Care, 53, 283, 10.1097/MLR.0000000000000315 · DOI
  16. Zhou, 2016, Utility of models to predict 28-day or 30-day unplanned hospital readmissions: an updated systematic review, BMJ Open, 6, e011060, 10.1136/bmjopen-2016-011060 · DOI
  17. Miller, 2014, Health information exchange, system size and information silos, J Health Econ, 33, 28, 10.1016/j.jhealeco.2013.10.004 · DOI
  18. Adler-Milstein, 2015, Electronic health record adoption in US hospitals: progress continues, but challenges persist, Health Aff, 34, 2174, 10.1377/hlthaff.2015.0992 · DOI · Paper page
  19. Goldstein, 2017, Opportunities and challenges in developing risk prediction models with electronic health records data: a systematic review, J Am Med Inform Assoc, 24, 198, 10.1093/jamia/ocw042 · DOI · Paper page
  20. Silva, 2006, Mortality assessment in intensive care units via adverse events using artificial neural networks, Artif Intell Med, 36, 223, 10.1016/j.artmed.2005.07.006 · DOI
  21. Gagne, 2011, A combined comorbidity score predicted mortality in elderly patients better than existing scores, J Clin Epidemiol, 64, 749, 10.1016/j.jclinepi.2010.10.004 · DOI · Paper page
  22. Tabak, 2013, Using electronic health record data to develop inpatient mortality predictive model: Acute Laboratory Risk of Mortality Score (ALaRMS), J Am Med Inform Assoc, 21, 455, 10.1136/amiajnl-2013-001790 · DOI · Paper page
  23. Makar, 2015, Short-term mortality prediction for elderly patients using Medicare claims data, Int J Mach Learn Comput, 5, 192, 10.7763/IJMLC.2015.V5.506 · DOI
  24. Awad, 2017, Early hospital mortality prediction of intensive care unit patients using an ensemble learning approach, Int J Med Inform, 108, 185, 10.1016/j.ijmedinf.2017.10.002 · DOI · Paper page
  25. He, 2014, Mining high-dimensional administrative claims data to predict early hospital readmissions, J Am Med Inform Assoc, 21, 272, 10.1136/amiajnl-2013-002151 · DOI
  26. Kharrazi, 2017, Comparing population-based risk-stratification model performance using demographic, diagnosis and medication data extracted from outpatient electronic health records versus administrative claims, Med Care, 55, 789, 10.1097/MLR.0000000000000754 · DOI
  27. Kharrazi, 2018, A practical comparison between the predictive power of population-based risk stratification models using data from electronic health records versus administrative claims: setting a baseline for future EHR-derived risk stratification models, Med Care, 56, 202, 10.1097/MLR.0000000000000849 · DOI
  28. Shadmi, 2011, Assessing socioeconomic health care utilization inequity in Israel: impact of alternative approaches to morbidity adjustment, BMC Public Health, 11, 609, 10.1186/1471-2458-11-609 · DOI
  29. Escobar, 2008, Risk-adjusting hospital inpatient mortality using automated inpatient, outpatient, and laboratory databases, Med Care, 46, 232, 10.1097/MLR.0b013e3181589bb6 · DOI
  30. Escobar, 2015, Nonelective rehospitalizations and postdischarge mortality: predictive models suitable for use in real time, Med Care, 53, 916, 10.1097/MLR.0000000000000435 · DOI
  31. Nguyen, 2016, Predicting all-cause readmissions using electronic health record data from the entire hospitalization: model development and comparison, J Hosp Med, 11, 473, 10.1002/jhm.2568 · DOI · Paper page
  32. Tonkikh, 2016, Functional status before and during acute hospitalization and readmission risk identification, J Hosp Med, 11, 636, 10.1002/jhm.2595 · DOI
  33. Bartkowiak, 2019, Validating the Electronic Cardiac Arrest Risk Triage (eCART) Score for risk stratification of surgical inpatients in the postoperative setting: retrospective cohort study, Ann Surg, 269, 1059, 10.1097/SLA.0000000000002665 · DOI
  34. Horne, 2017, Early inpatient calculation of laboratory-based 30-day readmission risk scores empowers clinical risk modification during index hospitalization, Am Heart J, 185, 101, 10.1016/j.ahj.2016.12.010 · DOI

Cited by

Sorted by citations

Metadata

Authors
Zeltzer, D., Balicer, R. D., Shir, T., Flaks-Manov, N., Einav, L., & Shadmi, E.
Affiliations
  • Tel Aviv University (IL)
  • Ben-Gurion University of the Negev (IL)
  • Clalit Health Services (IL)
  • Clalit Health Services, Clalit Research Institute, Tel Aviv
  • Department of Economics, Stanford University, Stanford, CA
Corresponding author
Zeltzer, Dan
Venue
Medical Care
Published
2019-07
Volume
57
Issue
7
Pages
551-559
ISSN
0025-7079 (ISSN-L)
OpenAlex
W2945965960
Cited by
34
References
5
Citations by year
2026: 2 · 2025: 2 · 2024: 8 · 2023: 4 · 2022: 5 · 2021: 9 · 2020: 3
FWCI
1.94
Type
journal article
Language
en
Open access
closed
Locations
  • Medical Care (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
  • Health Sciences › Health Professions › Health Information Management › Medical Coding and Health Information
  • Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
Keywords
electronic health records, health insurance claims, hospital readmission prediction, in-hospital mortality prediction, length of hospital stay, prediction accuracy, incremental predictive value, hospitalization outcomes
MeSH terms
Data Accuracy, Adult, Cause of Death, Female, Hospitalization, Humans, Insurance Claim Reporting, Israel, Length of Stay, Male, Middle Aged, Patient Readmission, Hospital Mortality, Electronic Health Records

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review