Functional Gastrointestinal Disorders and Joint Hypermobility: A School‐based Study
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The aim of the study was to assess the prevalence of joint hypermobility (JH) among school children with and without functional gastrointestinal disorders (FGIDs). School children completed validated Rome III questionnaires to diagnose FGID. Each child diagnosed with an FGID was matched for age and sex with a healthy control. The prevalence of JH in both groups was compared. A total of 654 school children participated in the study. One hundred forty-eight (22.6%) children were diagnosed with an FGID. Data from 136 FGIDs and 136 healthy controls were analyzed. Joint laxity was assessed to establish the Beighton score (≥4 was considered JH). There was no significant difference in JH between children with and without diagnoses of FGIDs odds ratio (OR) 1.03 (95% confidence interval [CI]: 0.59-1.81, P = 0.89). Multivariate analysis showed that younger age OR 2.31 (95% CI: 1.30-4.10, P = 0.004) and female sex OR 2.27 (95% CI: 1.22-4.24, P = 0.009) were significantly associated with JH. JH is equally prevalent in school children with and without FGIDs.
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Pediatric studies of populations of children with FGID using the Beighton score ≥ 4 cut off in the literature have been negative or uncontrolled.
“Pediatric studies of populations of children with FGID using the Beighton score ≥ 4 cut off in the literature [33, 45–47] have been negative or uncontrolled.”
From Pediatric joint hypermobility: a diagnostic framework and narrative review (2023) · cites this paper as [46]
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Epidemiology of Pediatric Functional Abdominal Pain Disorders: A Meta-Analysis
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Self-citationBeighton Score: A Valid Measure for Generalized Hypermobility in Children
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“This is relevant, as the Western Australian Pregnancy Cohort study (19) found that >60% of nonselected adolescent females had JH.”
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Pediatric joint hypermobility: a diagnostic framework and narrative review
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- Authors
- Saps, M., Blom, P. J. J., Velasco‐Benitez, C. A., & Benninga, M. A.
- Affiliations
- Nationwide Children's Hospital (US)
- University of Amsterdam (NL)
- Department of Pediatrics Universidad del Valle Cali Colombia
- Corresponding author
- Saps, Miguel
- Venue
- Journal of Pediatric Gastroenterology and Nutrition
- Publisher
- Wiley
- Published
- 2018-03
- Volume
- 66
- Issue
- 3
- Pages
- 387-390
- ISSN
- 0277-2116 (ISSN-L)
- 1536-4801
- OpenAlex
- W2752750356
- Cited by
- 19
- References
- 8
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 5 · 2020: 4 · 2019: 2 · 2018: 1
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- green
- pure.amsterdamumc.nl
- Licence
- Locations
- Journal of Pediatric Gastroenterology and Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Keywords
- functional gastrointestinal disorders, joint hypermobility, elementary school students, Beighton score, prevalence, age and sex association
- MeSH terms
- Adolescent, Child, Colombia, Cross-Sectional Studies, Female, Gastrointestinal Diseases, Humans, Joint Instability, Male, Risk Factors, Schools, Prevalence, Odds Ratio, Case-Control Studies
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