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Cited by 68Cancer survivorship and careChildhood Cancer Survivors' Quality of LifeCancer-related cognitive impairment studies

Quality of Life and Symptoms of Anxiety and Depression of Patients Receiving Cancer Chemotherapy: Longitudinal Study

Saevarsdottir, Thorunn, Fridriksdottir, Nanna, Gunnarsdottir, Sigridur·2010·Cancer Nursing
DOI 10.1097/ncc.0b013e3181b4adb5
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Abstract

In Brief The overall survival gain of cancer chemotherapy is estimated to be small, and some claim that it rarely improves quality of life (QOL). The purpose of this population-based study was to describe QOL and symptoms of anxiety and depression, over time, in a group of Icelandic cancer patients receiving chemotherapy. Quality of life was measured with the Icelandic version of Cancer Rehabilitation Evaluation System, Short Form (CARES-SF), and symptoms of anxiety and depression, with the Icelandic version of Hospital Anxiety and Depression Scale (HADS). Enrolled into the study were 144 patients, 90 women and 54 men; mean (SD) age was 55 (12.1) years. Although QOL was found relatively good during the period of chemotherapy, it was significantly worse after 3 and 6 months compared to baseline. Quality of life was found worst in the sexual and physical domains. At all time points, a significant association was found between symptoms of anxiety and depression and QOL with those reporting symptoms of either anxiety or depression experiencing worse QOL. The good QOL found during the period of chemotherapy is a positive finding. The results, however, call for an intense assessment, over time, of physical symptoms, anxiety, and depression, as well as sexuality issues. The overall survival gain of cancer chemotherapy is estimated to be small, and some claim that it rarely improves quality of life (QOL). The purpose of this population-based study was to describe QOL and symptoms of anxiety and depression, over time, in a group of Icelandic cancer patients receiving chemotherapy. Quality of life was measured with the Icelandic version of Cancer Rehabilitation Evaluation System, Short Form (CARES-SF), and symptoms of anxiety and depression, with the Icelandic version of Hospital Anxiety and Depression Scale (HADS). Enrolled into the study were 144 patients, 90 women and 54 men; mean (SD) age was 55 (12.1) years. Although QOL was found relatively good during the period of chemotherapy, it was significantly worse after 3 and 6 months compared to baseline. Quality of life was found worst in the sexual and physical domains. At all time points, a significant association was found between symptoms of anxiety and depression and QOL with those reporting symptoms of either anxiety or depression experiencing worse QOL. The good QOL found during the period of chemotherapy is a positive finding. The results, however, call for an intense assessment, over time, of physical symptoms, anxiety, and depression, as well as sexuality issues.

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Authors
Saevarsdottir, T., Fridriksdottir, N., & Gunnarsdottir, S.
Venue
Cancer Nursing
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2010-01
Volume
33
Issue
1
Pages
E1-E10
ISSN
0162-220X (ISSN-L)
DOI
10.1097/ncc.0b013e3181b4adb5
OpenAlex
W2081241438
Cited by
68
References
42
Citations by year
2026: 2 · 2025: 1 · 2024: 5 · 2023: 4 · 2022: 4 · 2021: 1 · 2020: 4 · 2019: 4 · 2018: 7 · 2017: 4 · 2016: 6 · 2015: 6 · 2014: 2 · 2013: 7 · 2012: 5
FWCI
1.82
Type
journal article
Language
en
Open access
closed
Locations
  • Cancer Nursing (publishedVersion)
  • PubMed (publishedVersion)
  • Hirsla (Landspítali University Hospital) (submittedVersion)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
Keywords
quality of life, cancer chemotherapy, anxiety, depression, sexual function, somatic symptoms, Hospital Anxiety and Depression Scale
MeSH terms
Adaptation, Psychological, Analysis of Variance, Antineoplastic Agents, Anxiety, Cross-Sectional Studies, Depression, Female, Humans, Ireland, Male, Middle Aged, Neoplasms, Prospective Studies, Psychometrics, Quality of Life, Surveys and Questionnaires, Risk Factors, Stress, Psychological

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