Joint Hypermobility, Fears, and Chocolate Consumption
Abstract
Our purpose was to evaluate joint hypermobility, an inherited disorder of the connective tissue significantly associated with anxiety disorders, in a sample of nonclinical students in relation to the frequency of severe fears and consumption of chocolate, coffee, cigarettes, and alcohol. One hundred fifty students completed the Hakim and Grahame Simple Questionnaire to detect hypermobility and the self-administered modified Wolpe Fear Scale (100 items). Severe fears and daily consumption of cigarettes, alcohol, coffee, and chocolate were compared with the hypermobility scores. We found significant differences when comparing severe fears between the groups with and without hypermobility (7.6 vs. 11; p = 0.001), reinforcing the hypothesis that the intensity of fears is greater in subjects with hypermobility. Only the frequency of chocolate intake was significantly higher among subjects with hypermobility (31.2% vs. 51.2%; p = 0.038) and may correspond to attempts of self-treatment of the collagen condition.
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The number of feared items and the severity of experienced fear and anxiety are significantly increased in adolescents and young adults with asymptomatic GJH compared with peers without GJH.
“The number of items that were indicated as fearful and the severity of the experienced fear and anxiety was significantly increased in adolescents and young adults with asymptomatic GJH compared to their peers without GJH.52”
From Role of Anxiety in Individuals with Generalized Joint Hypermobility: A Systematic Review (2025) · cites this paper as [52]
Cites
Hakim, A., & Grahame, R. (2003) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2003.tb10455.x · Cited by 312 · cited 1× · see citing works
“All participants filled the self-administered simple questionnaire to detect hypermobility by Hakim and Grahame (2003).”
The relationship between frequency and intensity of fears and a collagen condition
Bulbena, A., Gago, J., Sperry, L., & Bergé, D. (2006) · Depression and Anxiety · doi:10.1002/da.20160 · Cited by 35 · see citing works
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Smith, T. O., Easton, V., Bacon, H., Jerman, E., Armon, K., Poland, F., & Macgregor, A. J. (2014) · Rheumatology · doi:10.1093/rheumatology/ket317 · Cited by 130 · see citing works
Mulvey, M. R., Macfarlane, G. J., Beasley, M., Symmons, D. P. M., Lovell, K., Keeley, P., Woby, S., & McBeth, J. (2013) · Arthritis Care & Research · doi:10.1002/acr.21979 · Cited by 115 · see citing works
Sinibaldi, L., Ursini, G., & Castori, M. (2015) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics · doi:10.1002/ajmg.c.31430 · Cited by 87 · see citing works
Bulbena, A., Pailhez, G., Bulbena-Cabré, A., Mallorquí-Bagué, N., & Baeza-Velasco, C. (2015) · Advances in Psychosomatic Medicine · doi:10.1159/000369113 · Cited by 60 · see citing works
Self-citationAnxiety and joint hypermobility association: a systematic review
Bianchi Sanches, S. H., Osório, F. D. L., Udina, M., Martín-Santos, R., & Crippa, J. A. S. (2012) · Revista Brasileira de Psiquiatria · doi:10.1590/s1516-44462012000500005 · Cited by 29 · see citing works
Increased tobacco and alcohol use among women with joint hypermobility: a way to cope with anxiety?
Baeza-Velasco, C., Stoebner-Delbarre, A., Cousson-Gélie, F., Pailhez, G., Bulbena, A., Baguet, F., & Gély-Nargeot, M. C. (2015) · Rheumatology International · doi:10.1007/s00296-014-3053-8 · Cited by 16 · see citing works
Self-citationSanches, S. B., Osório, F. L., Louzada-Junior, P., Moraes, D., Crippa, J. A. S., & Martín-Santos, R. (2014) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2014.08.016 · Cited by 12 · see citing works
Role of Anxiety in Individuals with Generalized Joint Hypermobility: A Systematic Review
van Die-de Vries, J. E., Rameckers, E., Calders, P., Engelbert, R. H., Ramaekers, S. P., Goossens, M. E., & Verbunt, J. A. (2025) · Archives of Rehabilitation Research and Clinical Translation · doi:10.1016/j.arrct.2025.100467 · Cited by 1 · see citing works
- Authors
- Pailhez, G., Rosado, S., Bulbena Cabré, A., & Bulbena, A.
- Affiliations
- Hospital Del Mar (ES)
- Venue
- Journal of Nervous & Mental Disease
- Published
- 2011-11
- Volume
- 199
- Issue
- 11
- Pages
- 903-906
- ISSN
- 0022-3018 (ISSN-L)
- OpenAlex
- W2015740507
- Cited by
- 18
- References
- 2
- Citations by year
- 2026: 1 · 2025: 1 · 2022: 1 · 2019: 1 · 2016: 1 · 2015: 3 · 2014: 4 · 2013: 3 · 2012: 3
- FWCI
- 1.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Nervous and Mental Disease (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Health Professions › Pharmacy › Oral and gingival health research
- Keywords
- joint hypermobility, connective tissue diseases, anxiety disorders, chocolate consumption, coffee consumption, cigarette smoking, alcohol consumption, self-medication, students
- MeSH terms
- Adolescent, Cacao, Cross-Sectional Studies, Diet, Fear, Female, Humans, Joint Instability, Male, Sex Factors, Spain
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