The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
The MicroRNA-17-92 Family of MicroRNA Clusters in Development and Disease
Open accessAbstract
Overwhelming experimental evidence accumulated over the past decade indicates that microRNAs (miRNAs) are key regulators of gene expression in animals and plants and play important roles in development, homeostasis, and disease. The miR-17-92 family of miRNA clusters is composed of 3 related, highly conserved, polycistronic miRNA genes that collectively encode for a total of 15 miRNAs. We discuss recent studies demonstrating that these miRNAs are essential for vertebrate development and homeostasis. We also show how their mutation or deregulation contributes to the pathogenesis of a variety of human diseases, including cancer and congenital developmental defects. Finally, we discuss the current evidence suggesting how the different miRNAs encoded by these 3 clusters can functionally cooperate to fine-tune signaling and developmental pathways.
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1 retracted
Retracted: Post‐transcriptional regulation of the let‐7 microRNA during neural cell specification
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Cited by
Regulation of microRNA biogenesis and its crosstalk with other cellular pathways
Treiber, T., Treiber, N., & Meister, G. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0059-1 · Cited by 1,252
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A myriad of roles of miR-25 in health and disease
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Selective inhibition of miR‐92 in hippocampal neurons alters contextual fear memory
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Metadata
- Authors
- Concepcion, C. P., Bonetti, C., & Ventura, A.
- Venue
- The Cancer Journal
- Published
- 2012-05
- Volume
- 18
- Issue
- 3
- Pages
- 262-267
- ISSN
- 1528-9117 (ISSN-L)
- OpenAlex
- W2316081269
- Cited by
- 285
- References
- 85
- FWCI
- 4.62
- Type
- journal article
- Language
- en
- Open access
- green
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- Concepcion, C. P., Bonetti, C., & Ventura, A. (2012). The MicroRNA-17-92 Family of MicroRNA Clusters in Development and Disease. The Cancer Journal. https://doi.org/10.1097/ppo.0b013e318258b60a
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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