The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Fat Grafting: Evidence-Based Review on Autologous Fat Harvesting, Processing, Reinjection, and Storage
Abstract
Background: Over the past 20 years, there has been a dramatic increase in the use of autologous fat grafting to treat volume and contour defects in aesthetic and reconstructive surgery. It is generally accepted that fat grafting is safe, with good patient satisfaction. However, there are many procedural variations, and in terms of objective clinical effectiveness, the major disadvantage of this technique remains the unpredictable fat resorption rates and subsequent adverse events. Because of the rapidly evolving nature of this procedure, this review article provides an update on previous reviews by looking at the current evidence base regarding fat graft techniques and their effect on clinical outcome. Methods: A systematic review of the scientific literature listed on PubMed was performed using 20 search terms focused on harvesting, processing, reinjection, and conservation of fat grafting. An evidence-based system was used to determine eligibility for clinical and preclinical studies. Results: Thirty-seven articles were selected based on inclusion and exclusion criteria: five articles were clinical trials and 32 were experimental comparative studies examining human fat grafting. Conclusions: This systematic review revealed a lack of high-quality data despite the increase in fat grafting over the past 20 years. At present, there is no evidence that supports specific procedural standardization. Evidence-based studies that incorporate randomized controlled, prospective, multicenter trials are required to understand which factors influence positive fat grafting clinical outcomes.
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Cites
Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells
Rehman, J., Traktuev, D., Li, J., Merfeld-Clauss, S., Temm-Grove, C. J., Bovenkerk, J. E., Pell, C. L., Johnstone, B. H., Considine, R. V., & March, K. L. (2004) · Circulation · doi:10.1161/01.cir.0000121425.42966.f1 · Cited by 2,269
Structural Fat Grafting: More Than a Permanent Filler
Coleman, S. R. (2006) · Plastic & Reconstructive Surgery · doi:10.1097/01.prs.0000234610.81672.e7 · Cited by 1,282
Rigotti, G., Marchi, A., Gali??, M., Baroni, G., Benati, D., Krampera, M., Pasini, A., & Sbarbati, A. (2007) · Plastic and Reconstructive Surgery · doi:10.1097/01.prs.0000256047.47909.71 · Cited by 1,185
Facial Recontouring with Lipostructure
Coleman, S. R. (1997) · Clinics in Plastic Surgery · doi:10.1016/s0094-1298(20)31069-5 · Cited by 1,046
Improvement of Postnatal Neovascularization by Human Adipose Tissue-Derived Stem Cells
Miranville, A., Heeschen, C., Sengenès, C., Curat, C. A., Busse, R., & Bouloumié, A. (2004) · Circulation · doi:10.1161/01.cir.0000135466.16823.d0 · Cited by 899
Fat Grafting to the Breast Revisited: Safety and Efficacy
Coleman, S. R., & Saboeiro, A. P. (2007) · Plastic and Reconstructive Surgery · doi:10.1097/01.prs.0000252001.59162.c9 · Cited by 724
Matsumoto, D., Sato, K., Gonda, K., Takaki, Y., Shigeura, T., Sato, T., Aiba-Kojima, E., Iizuka, F., Inoue, K., Suga, H., et al. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.3375 · Cited by 624
Structural fat grafts: the ideal filler?
Coleman, S. R. (2001) · PubMed · Cited by 600
Nakagami, H., Maeda, K., Morishita, R., Iguchi, S., Nishikawa, T., Takami, Y., Kikuchi, Y., Saito, Y., Tamai, K., Ogihara, T., et al. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000190701.92007.6d · Cited by 577
Delay, E., Garson, S., Tousson, G., & Sinna, R. (2009) · Aesthetic Surgery Journal · doi:10.1016/j.asj.2009.08.010 · Cited by 536
Cited by
The Current State of Fat Grafting: A Review of Harvesting, Processing, and Injection Techniques
Strong, A. L., Cederna, P. S., Rubin, J. P., Coleman, S. R., & Levi, B. (2015) · Plastic and Reconstructive Surgery · doi:10.1097/prs.0000000000001590 · Cited by 436
Brown, M., Li, J., Moraes, C., Tabrizian, M., & Li-Jessen, N. Y. K. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121786 · Cited by 282
Avril, P., Duteille, F., Ridel, P., Heymann, M.-F., De Pinieux, G., Rédini, F., Blanchard, F., Heymann, D., Trichet, V., & Perrot, P. (2016) · Plastic and Reconstructive Surgery · doi:10.1097/01.prs.0000479989.88114.8b · Cited by 12
Metadata
- Authors
- Gir, P., Brown, S. A., Oni, G., Kashefi, N., Mojallal, A., & Rohrich, R. J.
- Venue
- Plastic & Reconstructive Surgery
- Published
- 2012-07
- Volume
- 130
- Issue
- 1
- Pages
- 249-258
- ISSN
- 0032-1052 (ISSN-L)
- OpenAlex
- W2318694763
- Cited by
- 334
- References
- 38
- FWCI
- 26.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Fat Grafting: Evidence-Based Review on Autologous Fat Harvesting, Processing, Reinjection, and Storage. https://app.cochat.ai/papers/10.1097/prs.0b013e318254b4d3
- The paper
- Gir, P., Brown, S. A., Oni, G., Kashefi, N., Mojallal, A., & Rohrich, R. J. (2012). Fat Grafting: Evidence-Based Review on Autologous Fat Harvesting, Processing, Reinjection, and Storage. Plastic & Reconstructive Surgery. https://doi.org/10.1097/prs.0b013e318254b4d3
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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