Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 172

The DOI matches its Crossref record.

Excellent Clinical Outcomes and High Retention in Care Among Adults in a Community-Based HIV Treatment Program in Rural Rwanda

Rich, Michael L., Miller, Ann C., Niyigena, Peter, Franke, Molly F., Niyonzima, Jean Bosco, Socci, Adrienne, Drobac, Peter C., Hakizamungu, Massudi, Mayfield, Alishya, Ruhayisha, Robert, Epino, Henry, Stulac, Sara, Cancedda, Corrado, Karamaga, Adolph, Niyonzima, Saleh, Yarbrough, Chase, Fleming, Julia, Amoroso, Cheryl, Mukherjee, Joia, Murray, Megan, Farmer, Paul, Binagwaho, Agnes·2012·JAIDS Journal of Acquired Immune Deficiency Syndromes
DOI 10.1097/qai.0b013e31824476c4
Open this paper in CoChat — free account

Abstract

BACKGROUND: Access to antiretroviral therapy (ART) has rapidly expanded; as of the end of 2010, an estimated 6.6 million people are receiving ART in low-income and middle-income countries. Few reports have focused on the experiences of rural health centers or the use of community health workers. We report clinical and programatic outcomes at 24 months for a cohort of patients enrolled in a community-based ART program in southeastern Rwanda under collaboration between Partners In Health and the Rwandan Ministry of Health. METHODS AND FINDINGS: A retrospective medical record review was performed for a cohort of 1041 HIV+ adult patients initiating community-based ART between June 1, 2005, and April 30, 2006. Key programatic elements included free ART with direct observation by community health worker, tuberculosis screening and treatment, nutritional support, a transportation allowance, and social support. Among 1041 patients who initiated community-based ART, 961 (92.3%) were retained in care, 52 (5%) died and 28 (2.7%) were lost to follow-up. Median CD4 T-cell count increase was 336 cells per microliter [interquartile range: (IQR): 212-493] from median 190 cells per microliter (IQR: 116-270) at initiation. CONCLUSIONS: A program of intensive community-based treatment support for ART in rural Rwanda had excellent outcomes in 24-month retention in care. Having committed to improving access to HIV treatment in sub-Saharan Africa, the international community, including country HIV programs, should set high programmatic outcome benchmarks.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1097/qai.0b013e31824476c4

Cites

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 26

  1. Rosen, 2007, Patient retention in antiretroviral therapy programs in sub-Saharan Africa: a systematic review., PLoS Med, 4, e298, 10.1371/journal.pmed.0040298 · DOI · Paper page
  2. Lawn, 2008, . Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa., AIDS, 22, 1897, 10.1097/QAD.0b013e32830007cd · DOI · Paper page
  3. Laurent, 2004, . Effectiveness and safety of a generic fixed-dose combination of nevirapine, stavudine, and lamivudine in HIV-1-infected adults in Cameroon: open-label multicentre trial., Lancet, 364, 29, 10.1016/S0140-6736(04)16586-0 · DOI · Paper page
  4. Koenig, 2004, Scaling-up HIV treatment programmes in resource-limited settings: the rural Haiti experience., AIDS, 18, S21, 10.1097/00002030-200406003-00005 · DOI · Paper page
  5. Bekker, 2006, . Rapid scale-up of a community-based HIV treatment service: programme performance over 3 consecutive years in Guguletu, South Africa., S Afr Med J, 96, 315
  6. Laurent, 2002, . The Senegalese governments highly active antiretroviral therapy initiative: an 18-month follow-up study., AIDS, 16, 1363, 10.1097/00002030-200207050-00008 · DOI · Paper page
  7. Zachariah, 2007, . Community support is associated with better antiretroviral treatment outcomes in a resource-limited rural district in Malawi., Trans R Soc Trop Med Hyg, 101, 79, 10.1016/j.trstmh.2006.05.010 · DOI
  8. Weidle, 2002, . Assessment of a pilot antiretroviral drug therapy programme in Uganda: patients response, survival, and drug resistance., Lancet, 360, 34, 10.1016/S0140-6736(02)09330-3 · DOI · Paper page
  9. Fox, 2010, Patient retention in antiretroviral therapy programs up to three years on treatment in sub-Saharan Africa, 2007-2009: systematic review., Trop Med Int Health, 15, 1, 10.1111/j.1365-3156.2010.02508.x · DOI · Paper page
  10. Chi, 2011, . Universal definition of loss to follow-up in HIV treatment programs: a statistical analysis of 111 facilities in Africa, Asia, and Latin America., PLoS Med, 9, e1001111, 10.1371/journal.pmed.1001111 · DOI · Paper page
  11. Mills, 2006, . Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis., JAMA, 296, 679, 10.1001/jama.296.6.679 · DOI · Paper page
  12. Tassie, 2010, . Trends in retention on antiretroviral therapy in national programs in low-income and middle-income countries., J Acquir Immune Defic Syndr, 54, 437, 10.1097/QAI.0b013e3181d73e1b · doi:10.1097/qai.0b013e3181d73e1b
  13. Hart, 2010, . Effect of directly observed therapy for highly active antiretroviral therapy on virologic, immunologic, and adherence outcomes: a meta-analysis and systematic review., J Acquir Immune Defic Syndr, 54, 167, 10.1097/QAI.0b013e3181d9a330 · DOI
  14. Behforouz, 2004, From directly observed therapy to accompagnateurs: enhancing AIDS treatment outcomes in Haiti and in Boston., Clin Infect Dis, 38, S429, 10.1086/421408 · DOI · Paper page
  15. Geng, 2010, . Retention in care among HIV-infected patients in resource-limited settings: emerging insights and new directions., Curr HIVAIDS Rep, 7, 234, 10.1007/s11904-010-0061-5 · DOI · Paper page
  16. Ivers, 2010, . Food assistance is associated with improved body mass index, food security and attendance at clinic in an HIV program in central Haiti: a prospective observational cohort study., AIDS Res Ther, 7, 33, 10.1186/1742-6405-7-33 · DOI
  17. Tuller, 2010, . Transportation costs impede sustained adherence and access to HAART in a clinic population in southwestern Uganda: a qualitative study., AIDS Behav, 14, 778, 10.1007/s10461-009-9533-2 · DOI · Paper page
  18. Beauliere, 2010, . The financial burden of morbidity in HIV-infected adults on antiretroviral therapy in Cote dIvoire., PLoS One, 5, e11213, 10.1371/journal.pone.0011213 · DOI
  19. Farmer, 2001, . Community-based approaches to HIV treatment in resource-poor settings., Lancet, 358, 404, 10.1016/S0140-6736(01)05550-7 · DOI · Paper page
  20. Walton, 2004, . Integrated HIV prevention and care strengthens primary health care: lessons from rural Haiti., J Public Health Policy, 25, 137, 10.1057/palgrave.jphp.3190013 · DOI · Paper page
  21. Munoz, 2010, . Community-based DOT-HAART accompaniment in an urban resource-poor setting., AIDS Behav, 14, 721, 10.1007/s10461-009-9559-5 · DOI
  22. Lowrance, 2009, . Adult clinical and immunologic outcomes of the national antiretroviral treatment program in Rwanda during 2004-2005., J Acquir Immune Defic Syndr, 52, 49, 10.1097/QAI.0b013e3181b03316 · DOI
  23. Toure, 2008, . Rapid scaling-up of antiretroviral therapy in 10,000 adults in Cote dIvoire: 2-year outcomes and determinants., AIDS, 22, 873, 10.1097/QAD.0b013e3282f768f8 · DOI
  24. Negin, 2011, . Anti-retroviral treatment outcomes among older adults in Zomba district, Malawi., PLoS One, 6, e26546, 10.1371/journal.pone.0026546 · DOI
  25. Nglazi, 2011, . Changes in programmatic outcomes during 7 years of scale-up at a community-based antiretroviral treatment service in South Africa., J Acquir Immune Defic Syndr, 56, E1, 10.1097/QAI.0b013e3181ff0bdc · DOI
  26. Dahab, 2008, . That is why I stopped the ART: patients providers perspectives on barriers to and enablers of HIV treatment adherence in a South African workplace programme., BMC Public Health, 8, 63, 10.1186/1471-2458-8-63 · DOI · Paper page

Cited by

See all 172

Metadata

Authors
Rich, M. L., Miller, A. C., Niyigena, P., Franke, M. F., Niyonzima, J. B., Socci, A., Drobac, P. C., Hakizamungu, M., Mayfield, A., Ruhayisha, R., Epino, H., Stulac, S., Cancedda, C., Karamaga, A., Niyonzima, S., Yarbrough, C., Fleming, J., Amoroso, C., Mukherjee, J., Murray, M., Farmer, P., & Binagwaho, A.
Venue
JAIDS Journal of Acquired Immune Deficiency Syndromes
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2012-03-01
Volume
59
Issue
3
Pages
e35-e42
ISSN
1525-4135 (ISSN-L)
DOI
10.1097/qai.0b013e31824476c4
OpenAlex
W2057543772
Cited by
172
References
0
FWCI
11.41
Type
journal article
Language
en
Open access
closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Excellent Clinical Outcomes and High Retention in Care Among Adults in a Community-Based HIV Treatment Program in Rural Rwanda. https://app.cochat.ai/papers/10.1097/qai.0b013e31824476c4
The paper
Rich, M. L., Miller, A. C., Niyigena, P., Franke, M. F., Niyonzima, J. B., Socci, A., Drobac, P. C., Hakizamungu, M., Mayfield, A., Ruhayisha, R., Epino, H., Stulac, S., Cancedda, C., Karamaga, A., Niyonzima, S., Yarbrough, C., Fleming, J., Amoroso, C., Mukherjee, J., . . . Binagwaho, A. (2012). Excellent Clinical Outcomes and High Retention in Care Among Adults in a Community-Based HIV Treatment Program in Rural Rwanda. JAIDS Journal of Acquired Immune Deficiency Syndromes. https://doi.org/10.1097/qai.0b013e31824476c4

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.