The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Sexually transmitted hepatitis C infection: the evolving epidemic in HIV-positive and HIV-negative MSM.
Abstract
PURPOSE OF REVIEW: The scale-up of direct-acting antiviral (DAA) therapy and introduction of preexposure prophylaxis (PrEP) has changed the epidemiology of sexually acquired hepatitis C virus (HCV) amongst HIV-positive and HIV-negative MSM. RECENT FINDINGS: Sexually acquired HCV continues to occur predominantly amongst HIV-positive MSM. Despite an increased uptake of DAA therapy the incidence of acute HCV has not declined consistently amongst HIV-positive MSM, likely a result of high infection and reinfection rates. Increasing cases of sexually acquired HCV have been reported amongst HIV-negative MSM accessing PrEP. Despite a lower prevalence of HCV at baseline, HIV-negative MSM accessing PrEP have an equally high overall incidence of HCV compared with HIV-positive MSM during follow-up. Behavioural factors (high-risk sexual behaviours and sexualized drug use) appear to be driving this HCV epidemic amongst MSM and effective behavioural interventions and early identification of reinfections are essential to control the HCV epidemic amongst MSM. SUMMARY: An improved understanding of the epidemiology of sexually acquired HCV will allow implementation of more effective public health interventions to control the transmission of HCV amongst HIV-positive and HIV-negative MSM.
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“HCV is not efficiently transmitted through sex (1333–1335).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [1333]
Citations
Cites
EASL Recommendations on Treatment of Hepatitis C 2018
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Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1
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Self-citationTerrault, N. A., Dodge, J. L., Murphy, E. L., Tavis, J. E., Kiss, A., Levin, T. R., Gish, R. G., Busch, M. P., Reingold, A. L., & Alter, M. J. (2013) · Hepatology · doi:10.1002/hep.26164 · Cited by 263
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Cited by
Sorted by citations
Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 3,018
Horberg, M. A., Thompson, M., Agwu, A. L., Colasanti, J. A., Haddad, M. S., Jain, M. K., McComsey, G. A., Radix, A., Rakhmanina, N. Y., Short, W. R., et al. (2024) · Clinical Infectious Diseases · doi:10.1093/cid/ciae479 · Cited by 169
for the ANRS-Prevagay group, Vaux, S., Chevaliez, S., Saboni, L., Sauvage, C., Sommen, C., Barin, F., Alexandre, A. F., Jauffret‐Roustide, M., Lot, F., et al. (2019) · BMC Infectious Diseases · doi:10.1186/s12879-019-3945-z · Cited by 53
Karimi, S. E., Bayani, A., Higgs, P., Bayat, A., Hemmat, M., Ahounbar, E., Armoon, B., & Fakhri, Y. (2020) · Substance Abuse Treatment Prevention and Policy · doi:10.1186/s13011-020-00306-1 · Cited by 30
Lourenço, L., Kelly, M., Tarasuk, J., Stairs, K., Bryson, M., Popovic, N., & Aho, J. (2021) · Canada Communicable Disease Report · doi:10.14745/ccdr.v47i12a01 · Cited by 29
Metadata
- Authors
- Lockart, I., Matthews, G. V., & Danta, M.
- Affiliations
- St Vincent's Hospital Sydney (AU)
- UNSW Sydney (AU)
- Corresponding author
- Danta, Mark
- Venue
- Current Opinion in Infectious Diseases
- Published
- 2019-02
- Volume
- 32
- Issue
- 1
- Pages
- 31-37
- ISSN
- 0951-7375 (ISSN-L)
- 1473-6527
- OpenAlex
- W2904186291
- Cited by
- 37
- References
- 45
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 4 · 2020: 12 · 2019: 5
- FWCI
- 0.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Hepatology › Hepatitis C virus research
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- hepatitis C virus, sexually transmitted infections, men who have sex with men, HIV-positive MSM, HIV-negative MSM, pre-exposure prophylaxis, direct-acting antivirals, HCV reinfection, HCV incidence, sexual risk behavior, chemsex, HCV epidemiology, behavioral interventions
- MeSH terms
- Antiviral Agents, Hepatitis C, Humans, Male, Sexually Transmitted Diseases, Viral, HIV Infections, Homosexuality, Male, Epidemics
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