Effects of a Weight and Pain Management Program in Patients With Rheumatoid Arthritis With Obesity: A Randomized Controlled Pilot Investigation

Somers, Tamara J.; Blumenthal, James A.; Dorfman, Caroline S.; Huffman, Kim M.; Edmond, Sara N.; Miller, Shannon N.; Wren, Anava A.; Caldwell, David; Keefe, Francis J.

doi:10.1097/rhu.0000000000001793

Cited by 13Rheumatoid Arthritis Research and TherapiesObesity and Health PracticesMusculoskeletal pain and rehabilitation

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Effects of a Weight and Pain Management Program in Patients With Rheumatoid Arthritis With Obesity: A Randomized Controlled Pilot Investigation

Somers, Tamara J., Blumenthal, James A., Dorfman, Caroline S., Huffman, Kim M., Edmond, Sara N., Miller, Shannon N., Wren, Anava A., Caldwell, David, Keefe, Francis J.·2022·JCR Journal of Clinical Rheumatology

DOI 10.1097/rhu.0000000000001793

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Abstract

Background Obesity is associated with poor outcomes for patients with rheumatoid arthritis (RA). Effective weight management is imperative. Although traditional lifestyle behavioral weight loss programs have demonstrated efficacy for reducing weight, these interventions do not meet the pain-related weight loss challenges of RA patients with obesity. Objective A 12-session group program (90 minutes per session) was developed integrating pain coping skills training into a lifestyle behavioral weight loss intervention. In addition to the weekly group sessions, participants engaged in supervised exercise sessions 3 times per week. Methods Through a small, pilot randomized trial, 50 participants were randomized to receive the intervention (n = 29) or standard care of RA (n = 21). Feasibility data (i.e., accrual, attrition, adherence) was examined using descriptive statistics (e.g., percent). We examined patterns of change in study outcomes from baseline to follow-up separately for the intervention and standard care arms using descriptive statistics and paired t tests. Effect sizes are also presented. Results Of those randomized to the intervention group,79.3% initiated treatment, with participants attending 74.3% of group skills sessions and 64.2% of exercise sessions. Intervention participants evidenced reductions in weight (mean, −2.28 kg) and waist circumference (mean, −4.76 cm) and improvements in physical functioning, eating behaviors, pain, and self-efficacy for weight control. Conclusions Findings suggest that incorporating a combined pain coping skills training and behavioral weight loss intervention into medical management of RA may improve outcomes. Study accrual and attrition, as well as intervention adherence, will inform future, larger randomized efficacy trials of the intervention. Retrospectively registered: January 29, 2020, NCT04246827

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There are several trials on weight-loss interventions in patients with chronic physical or mental illnesses, e.g., rheumatoid arthritis, breast cancer, mental disorders, and cardiovascular diseases.
“There are several trials on weight-loss interventions in patients with chronic physical or mental illnesses, e.g., rheumatoid arthritis, breast cancer, mental disorders, and cardiovascular diseases (44–47).”
From Cognitive-behavioral and dietary weight loss intervention in adult kidney transplant recipients with overweight and obesity: Results of a pilot RCT study (Adi-KTx) (2023) · cites this paper as [44]

ATS Statement: Guidelines for the Six-Minute Walk Test
(2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.166.1.at1102 · Cited by 11,195
Pain mechanisms: a new theory.
Melzack, R., & Wall, P. D. (1965) · Science · doi:10.1126/science.150.3699.971 · Cited by 11,108
Pain assessment: global use of the Brief Pain Inventory.
Cs, C., & Km, R. (1994) · PubMed · Cited by 5,178
Design and analysis of pilot studies: recommendations for good practice
Lancaster, G. A., Dodd, S., & Williamson, P. R. (2004) · Journal of Evaluation in Clinical Practice · doi:10.1111/j..2002.384.doc.x · Cited by 2,572 · cited 1×
“Given the pilot nature of this study, we did not conduct formal statistical analyses to test betweengroup differences.(36) Instead, we computed descriptive statistics and paired t tests to examine within-group changes from baseline to follow-up on study outcome variables.”
Method
The assessment of binge eating severity among obese persons
Gormally, J., Black, S., Daston, S., & Rardin, D. (1982) · Addictive Behaviors · doi:10.1016/0306-4603(82)90024-7 · Cited by 2,129
The role and interpretation of pilot studies in clinical research
Leon, A. C., Davis, L. L., & Kraemer, H. C. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.10.008 · Cited by 1,917 · cited 1×
“Given that this was a pilot feasibility study, outcome analyses were exploratory, and thus, results should be interpreted with caution.(38)”
Result
Development and evaluation of a scale to measure perceived self‐efficacy in people with arthritis
Lorig, K., Chastain, R. L., Ung, E., Shoor, S., & Holman, H. R. (1989) · Arthritis & Rheumatism · doi:10.1002/anr.1780320107 · Cited by 1,590
Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up
Franz, M. J., VanWormer, J. J., Crain, A. L., Boucher, J. L., Histon, T., Caplan, W., Bowman, J. D., & Pronk, N. P. (2007) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2007.07.017 · Cited by 1,559
Self-monitoring in weight loss: a systematic review of the literature
Burke, L. E., Wang, J., & Sevick, M. A. (2011) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2010.10.008 · Cited by 1,203
Cardiovascular death in rheumatoid arthritis: A population‐based study
Kremers, H. M., Nicola, P., Crowson, C. S., Ballman, K. V., & Gabriel, S. E. (2005) · Arthritis & Rheumatism · doi:10.1002/art.20878 · Cited by 942
AIMS2. The Content and Properties of a Revised and Expanded Arthritis Impact Measurement Scales Health Status Questionnaire
Meenan, R. F., Mason, J. H., Anderson, J. J., Guccione, A. A., & Kazis, L. E. (1992) · Arthritis & Rheumatism · doi:10.1002/art.1780350102 · Cited by 889
Self-efficacy in weight management.
Clark, M. M., Abrams, D. B., NIAURA, R. S., Eaton, C. A., & al, E. (1991) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.59.5.739 · Cited by 693
The association between chronic pain and obesity
Okifuji, A., & Hare, B. (2015) · Journal of Pain Research · doi:10.2147/jpr.s55598 · Cited by 597
Psychological Approaches to Understanding and Treating Disease-Related Pain
Keefe, F. J., Abernethy, A. P., & Campbell, L. C. (2004) · Annual Review of Psychology · doi:10.1146/annurev.psych.56.091103.070302 · Cited by 256
Self-citation
Psychological interventions for arthritis pain management in adults: A meta-analysis.
Dixon, K. E., Keefe, F. J., Scipio, C. D., Perri, L. M., & Abernethy, A. P. (2007) · Health Psychology · doi:10.1037/0278-6133.26.3.241 · Cited by 252
Self-citation
Abnormal body composition phenotypes in older rheumatoid arthritis patients: Association with disease characteristics and pharmacotherapies
Giles, J. T., Ling, S. M., Ferrucci, L., Bartlett, S. J., Andersen, R. E., Towns, M. C., Muller, D. C., Fontaine, K. R., & Bathon, J. M. (2008) · Arthritis Care & Research · doi:10.1002/art.23719 · Cited by 247
Obesity and Weight Loss in the Treatment and Prevention of Osteoarthritis
Vincent, H. K., Heywood, K., Connelly, J. O., & Hurley, R. W. (2012) · PM&R · doi:10.1016/j.pmrj.2012.01.005 · Cited by 236
Association of obesity with worse disease severity in rheumatoid arthritis as well as with comorbidities: A long‐term followup from disease onset
Ajeganova, S., Andersson, M., Hafström, I., & for the BARFOT Study Group (2012) · Arthritis Care & Research · doi:10.1002/acr.21710 · Cited by 229
Impact of Obesity on Remission and Disease Activity in Rheumatoid Arthritis: A Systematic Review and Meta‐Analysis
Liu, Y., Hazlewood, G. S., Kaplan, G. G., Eksteen, B., & Barnabe, C. C. M. (2016) · Arthritis Care & Research · doi:10.1002/acr.22932 · Cited by 226
Relationship between Body Weight Gain and Significant Knee, Hip, and Back Pain in Older Americans
Andersen, R. E., Crespo, C. J., Bartlett, S. J., Bathon, J. M., & Fontaine, K. R. (2003) · Obesity Research · doi:10.1038/oby.2003.159 · Cited by 179
Pain coping skills training and lifestyle behavioral weight management in patients with knee osteoarthritis: A randomized controlled study
Somers, T. J., Blumenthal, J. A., Guilak, F., Kraus, V. B., Schmitt, D. O., Babyak, M. A., Craighead, L. W., Caldwell, D. S., Rice, J. R., McKee, D. C., et al. (2012) · Pain · doi:10.1016/j.pain.2012.02.023 · Cited by 178
Self-citation
Redefining overweight and obesity in rheumatoid arthritis patients
Stavropoulos‐Kalinoglou, A., Metsios, G. S., Koutedakis, Y., Nevill, A. M., Douglas, K., Jamurtas, A. Z., Zanten, J. V., Labib, M., & Kitas, G. D. (2007) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.060319 · Cited by 172
Which traditional measures should be used in rheumatoid arthritis clinical trials?
Anderson, J. J., Felson, D. T., Meenan, R. F., & Williams, H. J. (1989) · Arthritis & Rheumatism · doi:10.1002/anr.1780320907 · Cited by 139
Effect of body mass index on mortality and clinical status in rheumatoid arthritis
Wolfe, F., & Michaud, K. D. (2012) · Arthritis Care & Research · doi:10.1002/acr.21627 · Cited by 131
Assessing the impact of self‐efficacy beliefs on adaptation to rheumatoid arthritis
Schiaffino, K. M., Revenson, T. A., & Gibofsky, A. (1991) · Arthritis & Rheumatism · doi:10.1002/art.1790040404 · Cited by 112
The Obesity Epidemic and Consequences for Rheumatoid Arthritis Care
George, M., & Baker, J. F. (2016) · Current Rheumatology Reports · doi:10.1007/s11926-015-0550-z · Cited by 103
Effect of weight reduction on the quality of life in obese patients with fibromyalgia syndrome: a randomized controlled trial
Senna, M. K., Sallam, R. A.-E. R., Ashour, H., & El-Arman, M. M. (2012) · Clinical Rheumatology · doi:10.1007/s10067-012-2053-x · Cited by 92
Impact of Bariatric Surgery on Patients With Rheumatoid Arthritis
Sparks, J. A., Halperin, F., Karlson, J. C., Karlson, E. W., & Bermas, B. L. (2015) · Arthritis Care & Research · doi:10.1002/acr.22629 · Cited by 91
Disease severity and domain‐specific arthritis self‐efficacy: Relationships to pain and functioning in patients with rheumatoid arthritis
Somers, T. J., Shelby, R. A., Keefe, F. J., Godiwala, N., Lumley, M. A., Mosley‐Williams, A., Rice, J. R., & Caldwell, D. S. (2010) · Arthritis Care & Research · doi:10.1002/acr.20127 · Cited by 66
Self-citation
Psychologic Interventions and Lifestyle Modifications for Arthritis Pain Management
Keefe, F. J., Somers, T. J., & Martire, L. M. (2008) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2008.03.001 · Cited by 60
Self-citation
Association of weight loss with improved disease activity in patients with rheumatoid arthritis: A retrospective analysis using electronic medical record data
Kreps, D. J., Halperin, F., Desai, S. P., Zhang, Z. Z., Losina, E., Olson, A., Karlson, E. W., Bermas, B. L., & Sparks, J. A. (2018) · International Journal of Clinical Rheumatology · doi:10.4172/1758-4272.1000154 · Cited by 47
Obesity, Weight Loss, and Progression of Disability in Rheumatoid Arthritis
Baker, J. F., England, B. R., Mikuls, T. R., Sayles, H. R., Cannon, G. W., Sauer, B. C., George, M., Caplan, L., & Michaud, K. D. (2018) · Arthritis Care & Research · doi:10.1002/acr.23579 · Cited by 44
Use of the Weight Efficacy Lifestyle Questionnaire with African American women: Validation and extension of previous findings
Dutton, G. R., Martin, P. D., Rhode, P. C., & Brantley, P. J. (2004) · Eating Behaviors · doi:10.1016/j.eatbeh.2004.04.005 · Cited by 43
The Relationship Between Pain and Eating among Overweight and Obese Individuals with Osteoarthritis: An Ecological Momentary Study
Choi, K. W., Somers, T. J., Babyak, M. A., Sikkema, K. J., Blumenthal, J. A., & Keefe, F. J. (2014) · Pain Research and Management · doi:10.1155/2014/598382 · Cited by 41
Self-citation
Maintenance of quality of life improvement for patients with chronic pain and obesity after interdisciplinary multimodal pain rehabilitation – A study using the Swedish Quality Registry for Pain Rehabilitation
Dong, H., Larsson, B. K., Fischer, M. R., & Gerdle, B. U. C. (2019) · European Journal of Pain · doi:10.1002/ejp.1457 · Cited by 22
Short-form arthritis impact measurement scales 2: Tests of reliability and validity among patients with osteoarthritis
Ren, X. S., Kazis, L., & Meenan, R. F. (1999) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199906)12:3

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Authors: Somers, T. J., Blumenthal, J. A., Dorfman, C. S., Huffman, K. M., Edmond, S. N., Miller, S. N., Wren, A. A., Caldwell, D., & Keefe, F. J.
Affiliations: Psychiatry and Behavioral Sciences
Duke Medical Center (US)
Yale University (US)
Stanford Medicine (US)
Duke University (US)
Corresponding author: Somers, Tamara J.
Blumenthal, James A.
Dorfman, Caroline S.
Miller, Shannon N.
Keefe, Francis J.
ORCID: Somers, Tamara J.
Blumenthal, James A.
Dorfman, Caroline S.
Huffman, Kim M.
Edmond, Sara N.
Wren, Anava A.
Keefe, Francis J.
Venue: JCR Journal of Clinical Rheumatology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2021-10-19
Volume: 28
Issue: 1
Pages: 7-13
ISSN: 1076-1608 (ISSN-L)
1536-7355
DOI: 10.1097/rhu.0000000000001793
OpenAlex: W4288063403
Cited by: 13
References: 36
Citations by year: 2026: 2 · 2025: 1 · 2024: 3 · 2023: 3 · 2022: 4
FWCI: 1.89
Type: journal article
Language: en
Open access: closed
Locations: JCR Journal of Clinical Rheumatology (publishedVersion)
Topics: Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity and Health Practices
Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Keywords: rheumatoid arthritis, obesity, weight management, pain coping skills training, behavioral weight loss, supervised exercise, physical function, dietary habits, waist circumference, intervention feasibility

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Effects of a Weight and Pain Management Program in Patients With Rheumatoid Arthritis With Obesity: A Randomized Controlled Pilot Investigation

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