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Cited by 973

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

World Allergy Organization Guidelines for the Assessment and Management of Anaphylaxis

Open access
Simons, F. Estelle R., Ardusso, Ledit R.F., Bilò, M. Beatrice, El-Gamal, Yehia M., Ledford, Dennis K., Ring, Johannes, Sanchez-Borges, Mario, Senna, Gian Enrico, Sheikh, Aziz, Thong, Bernard Y.·2011·World Allergy Organization Journal

Abstract

The illustrated World Allergy Organization (WAO) Anaphylaxis Guidelines were created in response to absence of global guidelines for anaphylaxis. Uniquely, before they were developed, lack of worldwide availability of essentials for the diagnosis and treatment of anaphylaxis was documented. They incorporate contributions from more than 100 allergy/immunology specialists on 6 continents. Recommendations are based on the best evidence available, supported by references published to the end of December 2010. The Guidelines review patient risk factors for severe or fatal anaphylaxis, co-factors that amplify anaphylaxis, and anaphylaxis in vulnerable patients, including pregnant women, infants, the elderly, and those with cardiovascular disease. They focus on the supreme importance of making a prompt clinical diagnosis and on the basic initial treatment that is urgently needed and should be possible even in a low resource environment. This involves having a written emergency protocol and rehearsing it regularly; then, as soon as anaphylaxis is diagnosed, promptly and simultaneously calling for help, injecting epinephrine (adrenaline) intramuscularly, and placing the patient on the back or in a position of comfort with the lower extremities elevated. When indicated, additional critically important steps include administering supplemental oxygen and maintaining the airway, establishing intravenous access and giving fluid resuscitation, and initiating cardiopulmonary resuscitation with continuous chest compressions. Vital signs and cardiorespiratory status should be monitored frequently and regularly (preferably, continuously). The Guidelines briefly review management of anaphylaxis refractory to basic initial treatment. They also emphasize preparation of the patient for self-treatment of anaphylaxis recurrences in the community, confirmation of anaphylaxis triggers, and prevention of recurrences through trigger avoidance and immunomodulation. Novel strategies for dissemination and implementation are summarized. A global agenda for anaphylaxis research is proposed.

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Metadata

Authors
Simons, F. E. R., Ardusso, L. R. F., Bilò, M. B., El-Gamal, Y. M., Ledford, D. K., Ring, J., Sanchez-Borges, M., Senna, G. E., Sheikh, A., & Thong, B. Y.
Venue
World Allergy Organization Journal
Publisher
Elsevier BV
Published
2011
Volume
4
Issue
2
Pages
13-37
ISSN
1939-4551 (ISSN-L)
OpenAlex
W2132885099
Cited by
973
References
8
FWCI
31.64
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: World Allergy Organization Guidelines for the Assessment and Management of Anaphylaxis. https://app.cochat.ai/papers/10.1097/wox.0b013e318211496c
The paper
Simons, F. E. R., Ardusso, L. R. F., Bilò, M. B., El-Gamal, Y. M., Ledford, D. K., Ring, J., Sanchez-Borges, M., Senna, G. E., Sheikh, A., & Thong, B. Y. (2011). World Allergy Organization Guidelines for the Assessment and Management of Anaphylaxis. World Allergy Organization Journal. https://doi.org/10.1097/wox.0b013e318211496c

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.