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Cited by 125Substance Abuse Treatment and OutcomesMental Health Treatment and AccessPersonality Disorders and Psychopathology

Comorbidity of psychiatric and substance use disorders in the United States: current issues and findings from the NESARC

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Hasin, Deborah, Kilcoyne, Bari·2012·Current Opinion in Psychiatry
DOI 10.1097/yco.0b013e3283523dccPMC PMC3767413
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Abstract

PURPOSE OF REVIEW: The comorbidity between psychiatric and substance use disorders remains an important phenomenon to understand, and an active area of investigation. The purpose of this review is to highlight key 2011 issues and novel findings on psychiatric and substance disorders comorbidity from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a large national survey of the US general population. RECENT FINDINGS: Topics of active investigation included the internalizing/externalizing meta-structure of common mental disorders; the 10 Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) personality disorders; the 3-year incidence and persistence of disorders; treatment of major depression; and many other topics not as easily categorized. SUMMARY: Meta-structure may increasingly offer a parsimonious way of addressing comorbidity, although adding new disorders adds complexity and the value of etiologic analyses utilizing broad dimensions of psychopathology rather than individual disorders is not yet fully known. Expanding the range of personality disorders beyond antisocial personality disorder appears essential in understanding the incidence and persistence of substance use disorders. Substance use disorders have low rates of treatment relative to major depression, but increase the likelihood of depression treatment among comorbid cases, a phenomenon that needs to be understood. These comorbidity studies provide much novel information, and indicate many potentially fruitful directions for new research.

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  • Half of those who meet diagnostic criteria for one disorder also meet diagnostic criteria for another disorder.

    “such that half of those who meet diagnostic criteria for one disorder also meet diagnostic criteria for another disorder.”

    From Atypical interoception as a common risk factor for psychopathology: A review (2021) · cites this paper as Hasin and Kilcoyne, 2012

    The Meta-Structure of Mental Disorders section discusses comorbidity among psychiatric and substance use disorders. It does not state that half of people meeting criteria for one disorder also meet criteria for another; searches for the quoted wording and a 50% prevalence figure did not establish that proportion. (LLM, conf=0.78)

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Authors
Hasin, D., & Kilcoyne, B.
Affiliations
Columbia University (US)
Corresponding author
Hasin, Deborah
ORCID
Hasin, Deborah
Venue
Current Opinion in Psychiatry
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2012-05
Volume
25
Issue
3
Pages
165-171
ISSN
0951-7367 (ISSN-L)
DOI
10.1097/yco.0b013e3283523dcc
PMC
PMC3767413
OpenAlex
W2036387589
Cited by
125
References
6
Citations by year
2026: 3 · 2025: 6 · 2024: 9 · 2023: 7 · 2022: 6 · 2021: 6 · 2020: 10 · 2019: 6 · 2018: 8 · 2017: 17 · 2016: 12 · 2015: 8 · 2014: 17 · 2013: 9 · 2012: 1
FWCI
1.40
Type
journal article
Language
en
Open access
Locations
  • Current Opinion in Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute on Alcohol Abuse and Alcoholism (U01AA018111, K05AA014223)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords
psychiatric comorbidity, substance use disorders, internalizing disorders, externalizing disorders, personality disorders, antisocial personality disorder, major depressive disorder, depression treatment, NESARC, DSM-IV, psychopathology dimensions
MeSH terms
Mental Disorders, Depressive Disorder, Humans, Internal-External Control, Personality Disorders, Risk Factors, United States, Comorbidity, Incidence, Substance-Related Disorders

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