Wide-field optical mapping of neural activity and brain haemodynamics: considerations and novel approaches

Ultrasensitive fluorescent proteins for imaging neuronal activity

Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature · doi:10.1038/nature12354 · Cited by 6,474

Millisecond-timescale, genetically targeted optical control of neural activity

Boyden, E. S., Zhang, F., Bamberg, E., Nagel, G., & Deisseroth, K. A. (2005) · Nature Neuroscience · doi:10.1038/nn1525 · Cited by 5,015

MCML—Monte Carlo modeling of light transport in multi-layered tissues

Wang, L. V., Jacques, S. L., & Zheng, L. (1995) · Computer Methods and Programs in Biomedicine · doi:10.1016/0169-2607(95)01640-f · Cited by 3,330

Capillary pericytes regulate cerebral blood flow in health and disease

Hall, C. N., Reynell, C., Gesslein, B., Hamilton, N. B., Mishra, A., Sutherland, B. A., O’Farrell, F. M., Buchan, A. M., Lauritzen, M., & Attwell, D. (2014) · Nature · doi:10.1038/nature13165 · Cited by 1,870

Functional architecture of cortex revealed by optical imaging of intrinsic signals

Grinvald, A., Lieke, E. E., Frostig, R. D., Gilbert, C. D., & Wiesel, T. N. (1986) · Nature · doi:10.1038/324361a0 · Cited by 1,243

Diversity of astrocyte functions and phenotypes in neural circuits

Khakh, B. S., & Sofroniew, M. V. (2015) · Nature Neuroscience · doi:10.1038/nn.4043 · Cited by 1,239

Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex

Ohki, K., Chung, S., Ch'ng, Y. H., Kara, P., & Reid, R. C. (2005) · Nature · doi:10.1038/nature03274 · Cited by 1,191

Miniaturized integration of a fluorescence microscope

Ghosh, K. K., Burns, L. D., Cocker, E. D., Nimmerjahn, A., Ziv, Y., Gamal, A. E., & Schnitzer, M. J. (2011) · Nature Methods · doi:10.1038/nmeth.1694 · Cited by 1,130

Interactions Between Electrical Activity and Cortical Microcirculation Revealed by Imaging Spectroscopy: Implications for Functional Brain Mapping

Malonek, D., & Grinvald, A. (1996) · Science · doi:10.1126/science.272.5261.551 · Cited by 1,109

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics

Akerboom, J., Calderón, N. C., Tian, L., Wabnig, S., Prigge, M., Tolö, J., Gordus, A. G., Orger, M. B., Severi, K. E., Macklin, J. J., et al. (2013) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2013.00002 · Cited by 736

Open-source statistical and data processing tools for wide-field optical imaging data in mice

Brier, L. M., & Culver, J. P. (2023) · Neurophotonics · doi:10.1117/1.nph.10.1.016601 · Cited by 20

Monitoring of Stimulus Evoked Murine Somatosensory Cortex Hemodynamic Activity With Volumetric Multi-Spectral Optoacoustic Tomography

Larney, B. M., Hutter, M. A., Degtyaruk, O., Deán‐Ben, X. L., & Razansky, D. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00536 · Cited by 19

Neurovascular coupling develops alongside neural circuits in the postnatal brain

Kozberg, M. G., & Hillman, E. M. C. (2016) · Neurogenesis · doi:10.1080/23262133.2016.1244439 · Cited by 20

Wide-field calcium imaging reveals widespread changes in cortical functional connectivity following mild traumatic brain injury in the mouse

Cramer, S. W., Haley, S. P., Popa, L. S., Carter, R. E., Scott, E. P., Flaherty, E. B., Dominguez, J., Aronson, J. D., Sabal, L. T., Surinach, D. A., et al. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105943 · Cited by 18

Spatiotemporal relationships between neuronal, metabolic, and hemodynamic signals in the awake and anesthetized mouse brain

Wang, X., Padawer-Curry, J. A., Bice, A. R., Kim, B., Rosenthal, Z. P., Lee, J., Goyal, M. S., Macauley, S. L., & Bauer, A. Q. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114723 · Cited by 23

Toward Community-Driven Big Open Brain Science: Open Big Data and Tools for Structure, Function, and Genetics

Charles, A. S., Falk, B., Turner, N. L., Pereira, T., Tward, D. J., Pedigo, B. D., Chung, J., Burns, R. C., Ghosh, S., Kebschull, J. M., et al. (2020) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-100119-110036 · Cited by 16

Neurovascular coupling: a review of spontaneous neocortical dynamics linking neuronal activity to hemodynamics and what we have learned from the rodent brain

Meyer-Baese, L., Jaeger, D., & Keilholz, S. D. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00418.2024 · Cited by 18

Imaging high-frequency voltage dynamics in multiple neuron classes of behaving mammals

Haziza, S., Chrapkiewicz, R., Zhang, Y., Kruzhilin, V., Li, J., Li, J., Delamare, G., Swanson, R. A., Buzsáki, G., Kannan, M., et al. (2025) · Cell · doi:10.1016/j.cell.2025.06.028 · Cited by 20

Electro-metabolic signaling

Longden, T. A., & Lederer, W. J. (2023) · The Journal of General Physiology · doi:10.1085/jgp.202313451 · Cited by 19

Detection of neural light-scattering activity in vivo: optical transmittance studies in the rat brain

Pan, W., Lee, S. Y., Billings, J., Nezafati, M., Majeed, W., Buckley, E. M., & Keilholz, S. D. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.06.039 · Cited by 17

Bidirectional alterations in brain temperature profoundly modulate spatiotemporal neurovascular responses in-vivo

Boorman, L. W., Harris, S., Shabir, O., Lee, L., Eyre, B., Howarth, C., & Berwick, J. (2023) · Communications Biology · doi:10.1038/s42003-023-04542-6 · Cited by 18

Bidirectional Neuronal Control of Epileptiform Activity by Repetitive Transcranial Focused Ultrasound Stimulations

Choi, T., Koo, M., Joo, J., Kim, T.-K., Shon, Y., & Park, J. (2023) · Advanced Science · doi:10.1002/advs.202302404 · Cited by 17

Imaging Cajal’s neuronal avalanche: how wide-field optical imaging of the point-spread advanced the understanding of neocortical structure–function relationship

Frostig, R., Chen-Bee, C. H., Johnson, B., & Jacobs, N. S. (2017) · Neurophotonics · doi:10.1117/1.nph.4.3.031217 · Cited by 16

Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer’s disease and neurological injury

Crouzet, C., Phan, T. P., Wilson, R. H., Shin, T. J., & Choi, B. (2023) · Neurophotonics · doi:10.1117/1.nph.10.2.020601 · Cited by 18

DEEP-squared: deep learning powered De-scattering with Excitation Patterning

Wijethilake, N., Anandakumar, M., Zheng, C., So, P. T. C., Yıldırım, M., & Wadduwage, D. N. (2023) · Light Science & Applications · doi:10.1038/s41377-023-01248-6 · Cited by 16

The oxygen initial dip in the brain of anesthetized and awake mice

Aydin, A.-K., Verdier, C., Chaigneau, E. M., & Charpak, S. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2200205119 · Cited by 15

Fiber photometry for monitoring cerebral oxygen saturation in freely-moving rodents

Yu, L., Thurston, E. M. S., Hashem, M., Dunn, J. F., Whelan, P. J., & Murari, K. (2020) · Biomedical Optics Express · doi:10.1364/boe.393295 · Cited by 15

Animal model of assessing cerebrovascular functional reserve by imaging photoplethysmography

Mamontov, O. V., Sokolov, A. Y., Volynsky, M. A., Osipchuk, A. V., Zaytsev, V. V., Владимирович, Р. Р., & Kamshilin, A. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-75824-w · Cited by 15

Nonlinear Evolution via Spatially-Dependent Linear Dynamics for Electrophysiology and Calcium DataPreprint

Hernandez, D., Moretti, A. K., Wei, Z., Saxena, S., Cunningham, J. P., & Paninski, L. (2018) · arXiv (Cornell University) · doi:10.48550/arxiv.1811.02459 · Cited by 14

The effects of locomotion on sensory-evoked haemodynamic responses in the cortex of awake mice

Eyre, B., Shaw, K., Sharp, P., Boorman, L., Lee, L., Shabir, O., Berwick, J., & Howarth, C. (2021) · Scientific Reports · doi:10.1038/s41598-022-10195-y · Cited by 14

Peripheral sensory stimulation elicits global slow waves by recruiting somatosensory cortex bilaterally

Rosenthal, Z. P., Raut, R. V., Bowen, R. M., Snyder, A. Z., Culver, J. P., Raichle, M. E., & Lee, J. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2021252118 · Cited by 16

Developmental Changes in Sensory-Evoked Optical Intrinsic Signals in the Rat Barrel Cortex

Sintsov, M., Suchkov, D., Khazipov, R., & Minlebaev, M. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00392 · Cited by 14

In vivo imaging for neurovascular disease research

Yoon, J., & Jeong, Y. (2019) · Archives of Pharmacal Research · doi:10.1007/s12272-019-01128-x · Cited by 13

Review of data processing of functional optical microscopy for neuroscience

Benisty, H., Song, A. K., Mishne, G., & Charles, A. S. (2022) · Neurophotonics · doi:10.1117/1.nph.9.4.041402 · Cited by 13

Building bridges: simultaneous multimodal neuroimaging approaches for exploring the organization of brain networks

Lake, E. M. R., & Higley, M. J. (2022) · Neurophotonics · doi:10.1117/1.nph.9.3.032202 · Cited by 13

The impact of vasomotion on analysis of rodent fMRI data

Lambers, H., Wachsmuth, L., Lippe, C., & Faber, C. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1064000 · Cited by 12

Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging – A Symposium Review

Marchant, J. K., Ferris, N. G., Grass, D., Allen, M. S., Gopalakrishnan, V., Olchanyi, M., Sehgal, D., Sheft, M., Strom, A., Bilgiç, B., et al. (2024) · Neuroinformatics · doi:10.1007/s12021-024-09686-2 · Cited by 14

Cortical Spreading Depolarizations in a Mouse Model of Subarachnoid Hemorrhage

Lai, J. H., Qin, T., Sakadžić, S., Ayata, C., & Chung, D. Y. (2022) · Neurocritical Care · doi:10.1007/s12028-021-01397-9 · Cited by 13

Activation and depression of neural and hemodynamic responses induced by the intracortical microstimulation and visual stimulation in the mouse visual cortex

Suematsu, N., Vazquez, A. L., & Kozai, T. D. Y. (2024) · Journal of Neural Engineering · doi:10.1088/1741-2552/ad3853 · Cited by 12

Peeking into the sleeping brain: Using in vivo imaging in rodents to understand the relationship between sleep and cognition

Sigl‐Glöckner, J., & Seibt, J. (2018) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2018.09.011 · Cited by 13

Optical imaging of stimulation-evoked cortical activity using GCaMP6f and jRGECO1a

Park, K., Liyanage, A. C., Koretsky, A. P., Pan, Y., & Du, C. (2020) · Quantitative Imaging in Medicine and Surgery · doi:10.21037/qims-20-921 · Cited by 13

Methodology for Cross-Talk Elimination in Simultaneous Voltage and Calcium Optical Mapping Measurements With Semasbestic Wavelengths

Uzelac, I., Crowley, C., Iravanian, S., Kim, T. Y., Cho, H. C., & Fenton, F. H. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.812968 · Cited by 13

Ultrafast Imaging of Physiological Brain Pulsations With Magnetic Resonance Encephalography—From Noise to Predictive Clinical Biomarker

Kiviniemi, V. J., Helakari, H., Raitamaa, L., Huotari, N., Rajna, Z., Järvelä, M., Elabasy, A., Tuunanen, J., Poltojainen, V., Väyrynen, T., et al. (2025) · NMR in Biomedicine · doi:10.1002/nbm.70092 · Cited by 11

Arousal state transitions occlude sensory-evoked neurovascular coupling in neonatal mice

Gheres, K. W., Ünsal, H. S., Han, X., Zhang, Q., Turner, K. L., Zhang, N., & Drew, P. J. (2023) · Communications Biology · doi:10.1038/s42003-023-05121-5 · Cited by 14

Somatostatin-expressing interneurons induce early NO-driven and late specific astrocyte-mediated vasodilation

Vo, T. T., Jung, W. B., Jin, T., Im, G. H., Lee, S., & Kim, S. (2025) · Nature Communications · doi:10.1038/s41467-025-61771-5 · Cited by 12

Time–frequency cross-coupling between cortical low-frequency neuronal calcium oscillations and blood oxygen metabolism evoked by ultrasound stimulation

Su, Z., Yan, J., Ji, H., Liu, M., Zhang, X., Xiaoli Li, A., & Yuan, Y. (2022) · Cerebral Cortex · doi:10.1093/cercor/bhac370 · Cited by 12

Study of neurovascular coupling by using mesoscopic and microscopic imaging

Chen, C., She, Z., Tang, P., Qin, Z., He, J., & Qu, J. Y. (2021) · iScience · doi:10.1016/j.isci.2021.103176 · Cited by 12

An open source statistical and data processing toolbox for wide-field optical imaging in micePreprint

Brier, L. M., & Culver, J. P. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.07.438885 · Cited by 12

Monitoring norepinephrine release in vivo using next-generation GRAB NE sensorsPreprint

Feng, J., Dong, H., Lischinsky, J. E., Zhou, J., Deng, F., Zhuang, C., Miao, X., Wang, H., Xie, H., Cui, G., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.06.22.546075 · Cited by 12

A cortex-wide multimodal microscope for simultaneous Ca2+ and hemodynamic imaging in awake mice

Qin, W., Li, T., Li, L., Jin, T., Li, B., Qi, W., Chen, Y., Li, H., Ruan, S., Guo, H., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64393-z · Cited by 11

High‐Efficiency Photoacoustic Microscopy for Ultrafast Hemodynamic Imaging

Qin, W., Li, T., Chen, Y., Liang, X., Li, L., Guo, H., Qi, W., & Xi, L. (2025) · Laser & Photonics Review · doi:10.1002/lpor.202401545 · Cited by 11

Determining the light scattering and absorption parameters from forward-directed flux measurements in cardiac tissue

Costantino, A., Hyatt, C. J., Kollisch-Singule, M. C., Beaumont, J., Roth, B. J., & Pertsov, A. M. (2017) · Journal of Biomedical Optics · doi:10.1117/1.jbo.22.7.076009 · Cited by 11

Characterization of cortical hemodynamic changes following sensory, visual, and speech activation by intraoperative optical imaging utilizing phase‐based evaluation methods

Oelschlägel, M., Polanski, W. H., Morgenstern, U., Steiner, G. R., Kirsch, M., Koch, E., Schackert, G., & Sobottka, S. B. (2021) · Human Brain Mapping · doi:10.1002/hbm.25674 · Cited by 11

Altered dorsal functional connectivity after post-weaning social isolation and resocialization in mice

Kim, G. S., Lee, H., & Jeong, Y. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118740 · Cited by 14

Measurement and visualization of stimulus-evoked tissue dynamics in mouse barrel cortex using phase-sensitive optical coherence tomography

Tang, P., Li, Y., Rakymzhan, A., Xie, Z., & Wang, R. K. (2020) · Biomedical Optics Express · doi:10.1364/boe.381332 · Cited by 11

The serotonin 2A receptor agonist 25CN-NBOH increases murine heart rate and neck-arterial blood flow in a temperature-dependent manner

Buchborn, T., Lyons, T., Song, C., Feilding, A., & Knöpfel, T. (2020) · Journal of Psychopharmacology · doi:10.1177/0269881120903465 · Cited by 13

A Multivariate Functional Connectivity Approach to Mapping Brain Networks and Imputing Neural Activity in Mice

Brier, L. M., Zhang, X., Bice, A. R., Gaines, S. H., Landsness, E. C., Lee, J., Anastasio, M. A., & Culver, J. P. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab282 · Cited by 11

Data-driven segmentation of cortical calcium dynamics

Weiser, S. C., Mullen, B. R., Ascencio, D., & Ackman, J. B. (2023) · PLoS Comput. Biol. · doi:10.1371/journal.pcbi.1011085 · Cited by 4

Wide-field imaging in behaving mice as a tool to study cognitive function

Gilad, A. (2024) · Neurophotonics · doi:10.1117/1.nph.11.3.033404 · Cited by 12

Attention-based CNN-BiLSTM for sleep state classification of spatiotemporal wide-field calcium imaging data

Zhang, X., Landsness, E. C., Miao, H., Chen, W., Tang, M., Brier, L. M., Culver, J. P., Lee, J., & Anastasio, M. A. (2024) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2024.110250 · Cited by 10

fMRI data acquisition and analysis for task-free, anesthetized rats

Vrooman, R. M., van den Berg, M., Desrosiers-Grégoire, G., van Engelenburg, W. A., Galteau, M. E., Lee, S., Veltien, A. A., Barrière, D. A., Cash, D., Chakravarty, M. M., et al. (2025) · Nature Protocols · doi:10.1038/s41596-024-01110-y · Cited by 11

Linking brain activity across scales with simultaneous opto- and electrophysiology

Hoffmann, A., & Helmchen, F. (2023) · Neurophotonics · doi:10.1117/1.nph.11.3.033403 · Cited by 12

A Longitudinal Pilot Study on Cognition and Cerebral Hemodynamics in a Mouse Model of Preeclampsia Superimposed on Hypertension: Looking at Mothers and Their Offspring

Trigiani, L. J., Lecrux, C., Royea, J., Lavoie, J. L., Lesage, F., Pilote, L., & Hamel, É. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.611984 · Cited by 10

Resting-state functional connectivity analysis of the mouse brain using intrinsic optical signal imaging of cerebral blood volume dynamics

Yoshida, Y., Nakao, M., & Katayama, N. (2018) · Physiological Measurement · doi:10.1088/1361-6579/aac033 · Cited by 10

Quantification of the effect of hemodynamic occlusion in two-photon imaging of mouse cortexPreprint

Yogesh, B., Heindorf, M., Jordan, R., & Keller, G. B. (2025) · eLife · doi:10.7554/elife.104914 · Cited by 10

Differences in the expression of cortex-wide neural dynamics are related to behavioral phenotype

MacDowell, C. J., Briones, B. A., Lenzi, M. J., Gustison, M. L., & Buschman, T. J. (2024) · Current Biology · doi:10.1016/j.cub.2024.02.004 · Cited by 12

Diverse and asymmetric patterns of single-neuron projectome in regulating interhemispheric connectivity

Fei, Y., Wu, Q., Zhao, S., Song, K., Han, J., & Liu, C. (2024) · Nature Communications · doi:10.1038/s41467-024-47762-y · Cited by 9

Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy

Chen, G., Carter, R. E., Cleary, J. D., Reid, T. S., Ranum, L. P. W., Swanson, M. S., & Ebner, T. J. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.01.003 · Cited by 11

Multiscale imaging informs translational mouse modeling of neurological disease

Wang, Y., LeDue, J. M., & Murphy, T. H. (2022) · Neuron · doi:10.1016/j.neuron.2022.09.006 · Cited by 13

Wide-Field Optical Imaging in Mouse Models of Ischemic Stroke

Padawer-Curry, J. A., Bowen, R. M., Jarang, A., Wang, X., Lee, J., & Bauer, A. Q. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2926-0_11 · Cited by 9

Transcranial cortex-wide Ca2+ imaging for the functional mapping of cortical dynamics

Yamada, S., Wang, Y., & Monai, H. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1119793 · Cited by 12

Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model

Bottom-Tanzer, S. F., Corella, S. G., Meyer, J. F., Sommer, M., Bolaños, L. A., Murphy, T. H., Quiñones, S., Heiney, S. A., Shtrahman, M., Whalen, M. J., et al. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae038 · Cited by 10

Cortical Networks Relating to Arousal Are Differentially Coupled to Neural Activity and Hemodynamics

Meyer-Baese, L., Morrissette, A. E., Wang, Y., Chatelier, B. L., Borden, P. Y., Keilholz, S. D., Stanley, G. B., & Jaeger, D. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.0298-23.2024 · Cited by 11

In vivo detection of GPCR-dependent signaling using fiber photometry and FRET-based biosensors

Jones-Tabah, J., Mohammad, H., Clarke, P. B. S., & Hébert, T. E. (2021) · Methods · doi:10.1016/j.ymeth.2021.05.002 · Cited by 9

Mesoscopic Mapping of Ictal Neurovascular Coupling in Awake Behaving Mice Using Optical Spectroscopy and Genetically Encoded Calcium Indicators

Yang, F., Li, J., Song, Y., Zhao, M., Niemeyer, J. E., Luo, P., Li, D., Lin, W., Ma, H., & Schwartz, T. H. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.704834 · Cited by 9

Modular head-mounted cortical imaging device for chronic monitoring of intrinsic signals in mice

Guinto, M. C., Haruta, M., Kurauchi, Y., Saigo, T., Kurasawa, K., Ryu, S., Ohta, Y., Kawahara, M., Takehara, H., Tashiro, H., et al. (2022) · Journal of Biomedical Optics · doi:10.1117/1.jbo.27.2.026501 · Cited by 9

Subdural CMOS optical probe (SCOPe) for bidirectional neural interfacingPreprint

Pollmann, E. H., Yin, H., Uguz, I., Dubey, A., Wingel, K., Choi, J. S., Moazeni, S., Gilhotra, Y., Andino-Pavlovsky, V., Banees, A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.07.527500 · Cited by 9

Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination

Doran, P. R., Fomin-Thunemann, N., Tang, R. P., Balog, D., Zimmerman, B., Kılıç, K., Martin, E. A., Kura, S., Fisher, H. P., Chabbott, G., et al. (2024) · Neurophotonics · doi:10.1117/1.nph.11.3.034310 · Cited by 8

Fiber-based lactate recordings with fluorescence resonance energy transfer sensors by applying a magnetic resonance-informed correction of hemodynamic artifacts

Lambers, H., Wachsmuth, L., Thomas, D., Boumezbeur, F., Hoesker, V., Pradier, B., & Faber, C. (2022) · Neurophotonics · doi:10.1117/1.nph.9.3.032212 · Cited by 9

State-of-the-Art Techniques to Causally Link Neural Plasticity to Functional Recovery in Experimental Stroke Research

Wahl, A.-S. (2018) · Neural Plasticity · doi:10.1155/2018/3846593 · Cited by 8

Movement and performance predict widespread cortical activity in a visual detection taskPreprint

Salkoff, D. B., Zagha, E., McCarthy, E., & McCormick, D. A. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/709642 · Cited by 8

Attention Decorrelates Sensory and Motor Signals in the Mouse Visual CortexPreprint

Abdolrahmani, M., Lyamzin, D. R., Aoki, R., & Benucci, A. (2021) · SSRN Electronic Journal · doi:10.1101/615229 · Cited by 8

Poster Viewing Sessions PB01-B01 to PB03-V09

Badji, A., de la Colina, A. N., Sabra, D., Karakuzu, A., Bherer, L., Lamarre-Cliche, M., Stikov, N., Gauthier, C. J., Cohen‐Adad, J., & Girouard, H. (2019) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x19851020 · Cited by 8

Dual-color GRAB sensors for monitoring spatiotemporal serotonin release in vivoPreprint

Deng, F., Wan, J., Li, G., Dong, H., Xia, X., Wang, Y., Li, X., Zhuang, C., Zheng, Y., Liu, L. D., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.05.27.542566 · Cited by 8

Longitudinal awake imaging of mouse deep brain microvasculature with super-resolution ultrasound localization microscopyPreprint

Wang, Y., Lowerison, M. R., Huang, Z., You, Q., Lin, B., Llano, D. A., & Song, P. (2024) · eLife · doi:10.7554/elife.95168 · Cited by 8

Microscopic deconstruction of cortical circuit stimulation by transcranial ultrasoundPreprint

Lemaire, T., Yuan, Y., Gellman, C., LeMessurier, A. M., Dray, S. R. H., Little, J. P., Froemke, R. C., & Shoham, S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.10.617091 · Cited by 10

Functional Brain Imaging Based on the Neurovascular Unit for Evaluating Neural Networks after Strok

Zhang, M. Y., Sun, M. Y., Zhang, M. L., Zhang, M. R., & Wang, P. S. (2022) · Advanced ultrasound in diagnosis and therapy · doi:10.37015/audt.2022.210033 · Cited by 7

Interactions between Arousal State and CO 2 Determine the Activity of Central Chemoreceptor Neurons That Drive Breathing

Souza, G. M. P. R., Stornetta, D. S., & Abbott, S. B. G. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1587-24.2024 · Cited by 10

Corticotropin-releasing hormone modulates NREM sleep consolidation through the thalamic reticular nucleus

Cumpana, L., Zanoletti, O., Kankanamge, D., Copits, B. A., Sandi, C., & Astori, S. (2025) · Nature Communications · doi:10.1038/s41467-025-63118-6 · Cited by 7

Longitudinal awake imaging of mouse deep brain microvasculature with super-resolution ultrasound localization microscopy

Wang, Y., Lowerison, M. R., Huang, Z., You, Q., Lin, B., Llano, D. A., & Song, P. (2025) · eLife · doi:10.7554/elife.95168.4 · Cited by 7

Extraction of the anisotropy factor and refractive index of biological tissue in the near-infrared region from diffusion approximation in the spatial frequency domain

Sarid, H., & Abookasis, D. (2021) · Optics Communications · doi:10.1016/j.optcom.2021.127749 · Cited by 7

Distinguishing motion artifacts during optical fiber-based in-vivo hemodynamics recordings from brain regions of freely moving rodents

Bisht, A., Simone, K., Bains, J. S., & Murari, K. (2024) · Neurophotonics · doi:10.1117/1.nph.11.s1.s11511 · Cited by 7

Vascular-Centric Mapping of in Vivo Blood Oxygen Saturation in Preclinical ModelsPreprint

Ren, Y., Senarathna, J., Chu, X., Grayson, W. L., & Pathak, A. P. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4251020 · Cited by 7

Alteration of functional connectivity despite preserved cerebral oxygenation during acute hypoxia

Bakker, M. E., Djerourou, I., Bélanger, S., Lesage, F., & Vanni, M. P. (2023) · Scientific Reports · doi:10.1038/s41598-023-40321-3 · Cited by 6

Decoding state-dependent cortical-cerebellar cellular functional connectivity in the mouse brain

Yan, Y., & Murphy, T. H. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114348 · Cited by 6

Chronic multiscale resolution of mouse brain networks using combined mesoscale cortical imaging and subcortical fiber photometry

Ramandi, D., Michelson, N. J., Raymond, L. A., & Murphy, T. H. (2023) · Neurophotonics · doi:10.1117/1.nph.10.1.015001 · Cited by 8

A comparative study of analytical models of diffuse reflectance in homogeneous biological tissues: Gelatin‐based phantoms and Monte Carlo experiments

Bahl, A., Ségaud, S., Xie, Y., Shapey, J., Bergholt, M. S., & Vercauteren, T. K. (2024) · Journal of Biophotonics · doi:10.1002/jbio.202300536 · Cited by 6

Toward an integrative neurovascular framework for studying brain networks

Guilbert, J., Légaré, A., Koninck, P. D., Desrosiers, P., & Desjardins, M. (2022) · Neurophotonics · doi:10.1117/1.nph.9.3.032211 · Cited by 9

Design and improve of the near-infrared phosphor by adjusting the energy levels or constructing new defects

Qiu, K., Zhang, H., Yuan, T., Shi, J., Wu, S., Meng, X., Liu, J., Li, P., Yang, Z., & Wang, Z. (2019) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2019.04.069 · Cited by 6

Stable behavioral state-specific large scale activity patterns in the developing cortex of neonates

Mojtahedi, N., Kovalchuk, Y., Böttcher, A., & Garaschuk, O. (2021) · Cell Calcium · doi:10.1016/j.ceca.2021.102448 · Cited by 6

Long-term development of dynamic changes in neurovascular coupling after acute temporal lobe epilepsy

Yin, L., Gao, D. S., Hu, J. M., Chen, Z., & Wang, X. (2022) · Brain Research · doi:10.1016/j.brainres.2022.147858 · Cited by 6

Mouse optical imaging for understanding resting-state functional connectivity in human fMRI

Matsui, T., Murakami, T., & Ohki, K. (2018) · Communicative & Integrative Biology · doi:10.1080/19420889.2018.1528821 · Cited by 6

Simultaneous mesoscopic Ca 2+ imaging and fMRI: Neuroimaging spanning spatiotemporal scalesPreprint

Lake, E. M. R., Ge, X., Shen, X., Hermán, P., Hyder, F., Cardin, J. A., Higley, M. J., Scheinost, D., Papademetris, X., Crair, M. C., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/464305 · Cited by 7

Rapid fluctuations in functional connectivity of cortical networks encode spontaneousPreprint

Benisty, H., Barson, D. G., Moberly, A. H., Lohani, S., Coifman, R. R., Mishne, G., Crair, M. C., Cardin, J. A., & Higley, M. J. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.08.15.456390 · Cited by 6

Coordinated Two‐Photon Fluorescence and Optoacoustic Microscopy of Neural, Vascular, and Cellular Dynamics in the Mouse Brain

Jin, T., Sundar, S., Liu, Y., Glück, C., Zhou, Q., Chen, Z., Reiss, M., Tang, L., Weber, B., & Razansky, D. (2025) · Laser & Photonics Review · doi:10.1002/lpor.202500102 · Cited by 5

Digital instrument simulator to optimize the development of hyperspectral systems: application for intraoperative functional brain mapping

Caredda, C., Lange, F., Giannoni, L., Ezhov, I., Picart, T., Guyotat, J., Tachtsidis, I., & Montcel, B. (2024) · Journal of Biomedical Optics · doi:10.1117/1.jbo.30.2.023513 · Cited by 5

Spatial proximity effects on cognitive processing of multimedia learning among college students: evidence from functional near-infrared spectroscopy

Ma, Y., Peng, Q., & Long, B. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1559696 · Cited by 5

Correcting for the hemoglobin absorption artifact in fiber photometry data

Zhang, R., & Kim, C. K. (2022) · Cell Reports Methods · doi:10.1016/j.crmeth.2022.100257 · Cited by 5

Excitatory–inhibitory mismatch shapes node recruitment in an epileptic network

Luo, P., Yang, F., Li, J., Niemeyer, J. E., Zhan, F., Estin, J., Zhao, M., Li, D., Lin, W., Liou, J.-Y., et al. (2023) · Epilepsia · doi:10.1111/epi.17638 · Cited by 5

Meso-Py: Dual Brain Cortical Calcium Imaging in Mice during Head-Fixed Social Stimulus Presentation

Michelson, N. J., Bolaños, F., Bolaños, L. A., Balbi, M., LeDue, J. M., & Murphy, T. H. (2023) · eNeuro · doi:10.1523/eneuro.0096-23.2023 · Cited by 12

Wide-field optical mapping of neural activity in awake mice and the importance of hemodynamic correction

Ma, Y., Thibodeaux, D. N., Shaik, M. A., Kim, S. H., & Hillman, E. M. C. (2017) · Optics in the Life Sciences · doi:10.1364/brain.2017.brs1b.3 · Cited by 2

Analysis of resting-state neurovascular coupling and locomotion-associated neural dynamics using wide-field optical mapping

Ma, Y. (2018) · doi:10.7916/d8nz9r8p · Cited by 1

Wide-field optical imaging along the neurovascular coupling pathway

Wang, X., Bice, A. R., & Bauer, A. Q. (2020) · Optics in the Life Sciences · doi:10.1364/brain.2020.bw2c.5

Simultaneous Multi-Wavelength Optical Imaging of Neuronal and Hemodynamic Activity

Ma, H., Zhao, M., Harris, S., & Schwartz, T. H. (2014) · Neuromethods · doi:10.1007/978-1-4939-0724-3_12 · Cited by 11

Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain

Gottschalk, S., Degtyaruk, O., Larney, B. M., Rebling, J., Hutter, M. A., Deán‐Ben, X. L., Shoham, S., & Razansky, D. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0372-9 · Cited by 233