The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.
Quorum sensing in bacterial virulence
Abstract
Bacteria communicate through the production of diffusible signal molecules termed autoinducers. The molecules are produced at basal levels and accumulate during growth. Once a critical concentration has been reached, autoinducers can activate or repress a number of target genes. Because the control of gene expression by autoinducers is cell-density-dependent, this phenomenon has been called quorum sensing. Quorum sensing controls virulence gene expression in numerous micro-organisms. In some cases, this phenomenon has proven relevant for bacterial virulence in vivo. In this article, we provide a few examples to illustrate how quorum sensing can act to control bacterial virulence in a multitude of ways. Several classes of autoinducers have been described to date and we present examples of how each of the major types of autoinducer can be involved in bacterial virulence. As quorum sensing controls virulence, it has been considered an attractive target for the development of new therapeutic strategies. We discuss some of the new strategies to combat bacterial virulence based on the inhibition of bacterial quorum sensing systems.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm
Davies, D. G., Parsek, M. R., Pearson, J. P., Iglewski, B. H., Costerton, J. W., & Greenberg, E. P. (1998) · Science · doi:10.1126/science.280.5361.295 · Cited by 3,396
Fuqua, W. C., Winans, S. C., & Greenberg, E. P. (1994) · Journal of Bacteriology · doi:10.1128/jb.176.2.269-275.1994 · Cited by 2,927
Bacterial Quorum-Sensing Network Architectures
Ng, W.-L., & Bassler, B. L. (2009) · Annual Review of Genetics · doi:10.1146/annurev-genet-102108-134304 · Cited by 1,679
Quorum-sensing in Gram-negative bacteria
Whitehead, N. (2001) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(01)00059-6 · Cited by 1,607
Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
Singh, P. K., Schaefer, A. L., Parsek, M. R., Moninger, T. O., Welsh, M. J., & Greenberg, E. P. (2000) · Nature · doi:10.1038/35037627 · Cited by 1,519
Regulation of Gene Expression by Cell-to-Cell Communication: Acyl-Homoserine Lactone Quorum Sensing
Fuqua, C., Parsek, M. R., & Greenberg, E. P. (2001) · Annual Review of Genetics · doi:10.1146/annurev.genet.35.102401.090913 · Cited by 1,388
Establishment of infection: lessons from a versatile opportunist
Lyczak, J. B., Cannon, C. L., & Pier, G. B. (2000) · Microbes and Infection · doi:10.1016/s1286-4579(00)01259-4 · Cited by 1,341
Social evolution theory for microorganisms
West, S. A., Griffin, A. S., Gardner, A., & Diggle, S. P. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1461 · Cited by 1,190
Jarraud, S., Mougel, C., Thioulouse, J., Lina, G., Meugnier, H., Forey, F., Nesme, X., Etienne, J., & Vandenesch, F. (2002) · Infection and Immunity · doi:10.1128/iai.70.2.631-641.2002 · Cited by 1,151
Schuster, M., Lostroh, C. P., Ogi, T., & Greenberg, E. P. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.7.2066-2079.2003 · Cited by 1,126
Cited by
Ecology and Genomic Insights into Plant-Pathogenic and Plant-Nonpathogenic Endophytes
Brader, G., Compant, S., Vescio, K., Mitter, B., Trognitz, F., Ma, L.-J., & Sessitsch, A. (2017) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-080516-035641 · Cited by 482
Evolution of virulence in opportunistic pathogens: generalism, plasticity, and control
Brown, S. P., Cornforth, D. M., & Mideo, N. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.04.005 · Cited by 416
Vandeputte, O. M., Kiendrebeogo, M., Rasamiravaka, T., Stévigny, C., Duez, P., Rajaonson, S., Diallo, B., Mol, A., Baucher, M., & El Jaziri, M. (2011) · Microbiology · doi:10.1099/mic.0.049338-0 · Cited by 293
Nitric oxide regulation of bacterial biofilms
Arora, D. P., Hossain, S., Xu, Y., & Boon, E. M. (2015) · Biochemistry · doi:10.1021/bi501476n · Cited by 206
Kim, S. M., Park, J. H., Lee, H. S., Kim, W. B., Ryu, J. M., Han, H. J., & Choi, S. H. (2013) · Infection and Immunity · doi:10.1128/iai.00561-13 · Cited by 75
Metadata
- Authors
- Antunes, L. C. M., Ferreira, R. B. R., Buckner, M. M. C., & Finlay, B. B.
- Venue
- Microbiology
- Publisher
- Microbiology Society
- Published
- 2010-08-01
- Volume
- 156
- Issue
- 8
- Pages
- 2271-2282
- ISSN
- 1350-0872 (ISSN-L)
- 1465-2080
- OpenAlex
- W2101051206
- Cited by
- 537
- References
- 135
- FWCI
- 13.82
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Quorum sensing in bacterial virulence. https://app.cochat.ai/papers/10.1099/mic.0.038794-0
- The paper
- Antunes, L. C. M., Ferreira, R. B. R., Buckner, M. M. C., & Finlay, B. B. (2010). Quorum sensing in bacterial virulence. Microbiology. https://doi.org/10.1099/mic.0.038794-0
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
