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Untitled work

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The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease

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Imaging light responses of foveal ganglion cells in the living macaque eye

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Safety and Biodistribution Evaluation in Cynomolgus Macaques of rAAV2tYF-CB-hRS1, a Recombinant Adeno-Associated Virus Vector Expressing Retinoschisin

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Optimization of laser-induced choroidal neovascularization in African green monkeys

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Tetramerization and interdomain flexibility of the replication initiation controller YabA enables simultaneous binding to multiple partners

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Directed Evolution of AAV for Efficient Gene Delivery to Canine and Primate Retina - Raw counts of variants from deep sequencing

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617. Identification of Novel AAV Capsid Variants with Enhanced Tropism for the Canine Outer Retina Following Intravitreal Delivery

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Directed evolution identifies novel AAV capsid variants for targeting the canine outer retina following intravitreal delivery

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Optogenetic Therapy for Visual Restoration

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Adeno-Associated Virus (AAV) - Based Gene Therapies for Retinal Diseases: Where are We?

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AAV-Based Strategies for Treatment of Retinal and Choroidal Vascular Diseases: Advances in Age-Related Macular Degeneration and Diabetic Retinopathy Therapies

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Gene Therapies in Clinical Development to Treat Retinal Disorders

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Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy

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Retina-directed gene therapy: Achievements and remaining challenges

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Gene therapy for age-related macular degeneration: a promising frontier in vision preservation

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Adeno-associated virus vectors for retinal gene therapy in basic research and clinical studies

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A Deep Learning Approach to Improve Retinal Structural Predictions and Aid Glaucoma Neuroprotective Clinical Trial Design

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Toward successful retinal drug delivery after intravitreal injection: Current strategies to overcome the inner limiting membrane

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Developing New Vectors for Retinal Gene TherapyPreprint

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Preclinical evaluation of NG101, a potential AAV gene therapy for wet age-related macular degeneration

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The Central Role of Oxidative Stress in Diabetic Retinopathy: Advances in Pathogenesis, Diagnosis, and Therapy

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AAV-based gene therapies for neovascular AMD

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A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization

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Structural dynamics insights into principles underlying the fitness of new broadly potent AAVsPreprint

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Recent Development in in vivo Clinical Gene Therapy Platforms

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Directed evolution of adeno associated virus (AAV) for retinal gene therapy

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Viability of engineered AAVs via protein language modelsPreprint

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In vivo–directed evolution of adeno-associated virus in the primate retina

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Novel AAV variants isolated by directed evolution in primate display enhanced retinal transduction following intravitreal injection

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In Vivo–Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

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Identification of AAV Capsids with Enhanced Intravitreal Transduction and Favorable Safety Profile in Non-Human PrimatesPreprint

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Design and Characterization of a Novel Intravitreal Dual-Transgene Genetic Medicine for Neovascular Retinopathies

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