PreprintCited by 4Artificial Intelligence in Healthcare and EducationArtificial Intelligence in HealthcareMusculoskeletal Disorders and Rehabilitation

Assessing the performance of GPT-4 in the filed of osteoarthritis and orthopaedic case consultation

Open access
Li, Juntan, Gao, Xiang, Dou, Tianxu, Gao, Yuyang, Zhu, Wannan·2023·medRxiv

Abstract

Background: Large Language Models (LLMs) like GPT-4 demonstrate potential applications in diverse areas, including healthcare and patient education. This study evaluates GPT-4’s competency against osteoarthritis (OA) treatment guidelines from the United States and China and assesses its ability in diagnosing and treating orthopedic diseases. Methods: Data sources included OA management guidelines and orthopedic examination case questions. Queries were directed to GPT-4 based on these resources, and its responses were compared with the established guidelines and cases. The accuracy and completeness of GPT-4’s responses were evaluated using Likert scales, while case inquiries were stratified into four tiers of correctness and completeness. Results: GPT-4 exhibited strong performance in providing accurate and complete responses to OA management recommendations from both the American and Chinese guidelines, with high Likert scale scores for accuracy and completeness. It demonstrated proficiency in handling clinical cases, making accurate diagnoses, suggesting appropriate tests, and proposing treatment plans. Few errors were noted in specific complex cases. Conclusions: GPT-4 exhibits potential as an auxiliary tool in orthopedic clinical practice and patient education, demonstrating high accuracy and completeness in interpreting OA treatment guidelines and analyzing clinical cases. Further validation of its capabilities in real-world clinical scenarios is needed.

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Crossref · 10.1101/2023.08.06.23293735

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Research works printed but not linked: 4

  1. Ashish Vaswani, Noam Shazeer, Niki Parmar, Jakob Uszkoreit, Llion Jones, Aidan N Gomez, Łukasz Kaiser, Illia Polosukhin. Attention is all you need. Advances in neural information processing systems. 2017;30
  2. P. Lee, S. Bubeck, J. Petro. Benefits, Limits, and Risks of GPT-4 as an AI Chatbot for Medicine. Reply. N Engl J Med. 2023;388(25):2400.
  3. Qing Lyu, Josh Tan, Michael E Zapadka, Janardhana Ponnatapura, Chuang Niu, Kyle J Myers, Ge Wang, Christopher T Whitlow. Translating radiology reports into plain language using ChatGPT and GPT-4 with prompt learning: results, limitations, and potential. Visual Computing for Industry, Biomedicine, and Art. 2023;6(1):9.
  4. Sajan B Patel, Kyle Lam, Michael Liebrenz. ChatGPT: friend or foe. Lancet Digit. Health. 2023;5:e102.

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Authors
Li, J., Gao, X., Dou, T., Gao, Y., & Zhu, W.
Affiliations
  • First Hospital of China Medical University (CN)
  • Fourth Affiliated Hospital of China Medical University (CN)
  • Jinzhou Medical University (CN)
Corresponding author
Zhu, Wannan
Venue
medRxiv
Publisher
openRxiv
Published
2023-08-09
OpenAlex
W4385766957
Cited by
4
References
26
Citations by year
2025: 2 · 2024: 2
Type
posted content
Language
en
Open access
Locations
medRxiv (acceptedVersion)
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
  • Health Sciences › Medicine › Rehabilitation › Musculoskeletal Disorders and Rehabilitation
Keywords
GPT-4, large language models, osteoarthritis, orthopedic diagnosis, treatment guidelines, AI-assisted diagnosis, patient education, clinical decision support

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