The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
The Ca2+ Pumps of the Endoplasmic Reticulum and Golgi Apparatus
Open accessAbstract
The various splice variants of the three SERCA- and the two SPCA-pump genes in higher vertebrates encode P-type ATPases of the P(2A) group found respectively in the membranes of the endoplasmic reticulum and the secretory pathway. Of these, SERCA2b and SPCA1a represent the housekeeping isoforms. The SERCA2b form is characterized by a luminal carboxy terminus imposing a higher affinity for cytosolic Ca(2+) compared to the other SERCAs. This is mediated by intramembrane and luminal interactions of this extension with the pump. Other known affinity modulators like phospholamban and sarcolipin decrease the affinity for Ca(2+). The number of proteins reported to interact with SERCA is rapidly growing. Here, we limit the discussion to those for which the interaction site with the ATPase is specified: HAX-1, calumenin, histidine-rich Ca(2+)-binding protein, and indirectly calreticulin, calnexin, and ERp57. The role of the phylogenetically older and structurally simpler SPCAs as transporters of Ca(2+), but also of Mn(2+), is also addressed.
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Cites
NAADP mobilizes calcium from acidic organelles through two-pore channels
Calcraft, P. J., Ruas, M., Pan, Z., Cheng, X., Arredouani, A., Hao, X., Tang, J., Rietdorf, K., Teboul, L., Chuang, K.-T., et al. (2009) · Nature · doi:10.1038/nature08030 · Cited by 760
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease
Sakuntabhai, A., Ruiz-Perez, V., Carter, S., Jacobsen, N., Burge, S., Monk, S., Smith, M., Munro, C. S., O'Donovan, M., Craddock, N., et al. (1999) · Nature Genetics · doi:10.1038/6784 · Cited by 740
Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease
Hu, Z., Bonifas, J. M., Beech, J., Bench, G., Shigihara, T., Ogawa, H., Ikeda, S., Mauro, T., & Epstein, E. H. (2000) · Nature Genetics · doi:10.1038/71701 · Cited by 567
Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca2+ pump
Sudbrak, R. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.7.1131 · Cited by 321
Cited by
La Rovere, R. M. L., Roest, G., Bultynck, G., & Parys, J. B. (2016) · Cell Calcium · doi:10.1016/j.ceca.2016.04.005 · Cited by 257
Mitochondria‐associated endoplasmic reticulum membrane: Overview and inextricable link with cancer
Yang, X., Zhuang, J., Song, W., Shen, W., Wu, W., Shen, H., & Han, S. (2023) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17696 · Cited by 55
Metadata
- Authors
- Vandecaetsbeek, I., Vangheluwe, P., Raeymaekers, L., Wuytack, F., & Vanoevelen, J.
- Venue
- Cold Spring Harbor Perspectives in Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2011-02-09
- Volume
- 3
- Issue
- 5
- Pages
- a004184-a004184
- ISSN
- 1943-0264 (ISSN-L)
- OpenAlex
- W2154150494
- Cited by
- 221
- References
- 4
- Type
- posted content
- Language
- en
- Open access
- bronze
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- Vandecaetsbeek, I., Vangheluwe, P., Raeymaekers, L., Wuytack, F., & Vanoevelen, J. (2011). The Ca2+ Pumps of the Endoplasmic Reticulum and Golgi Apparatus. Cold Spring Harbor Perspectives in Biology. https://doi.org/10.1101/cshperspect.a004184
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