The DOI matches its Crossref record; 230 of the 230 references it cites were found in a registry or an index.
The Role of Autophagy in Parkinson's Disease
Open accessAbstract
Great progress has been made toward understanding the pathogenesis of Parkinson's disease (PD) during the past two decades, mainly as a consequence of the discovery of specific gene mutations contributing to the onset of PD. Recently, dysregulation of the autophagy pathway has been observed in the brains of PD patients and in animal models of PD, indicating the emerging role of autophagy in this disease. Indeed, autophagy is increasingly implicated in a number of pathophysiologies, including various neurodegenerative diseases. This article will lead you through the connection between autophagy and PD by introducing the concept and physiological function of autophagy, and the proteins related to autosomal dominant and autosomal recessive PD, particularly α-synuclein and PINK1-PARKIN, as they pertain to autophagy.
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Cited by
Autophagy in Human Health and Disease
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Defects in trafficking bridge Parkinson’s disease pathology and genetics
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Review: Sporadic Parkinson's disease: development and distribution of α‐synuclein pathology
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Roles of Autophagy in Oxidative Stress
Yun, H. R., Jo, Y. H., Kim, J., Shin, Y., Kim, S. S., & Choi, T. G. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093289 · Cited by 396
Metadata
- Authors
- Lynch-Day, M. A., Mao, K., Wang, K., Zhao, M., & Klionsky, D. J.
- Venue
- Cold Spring Harbor Perspectives in Medicine
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2012-02-15
- Volume
- 2
- Issue
- 4
- Pages
- a009357-a009357
- ISSN
- 2157-1422 (ISSN-L)
- OpenAlex
- W2160854976
- Cited by
- 458
- References
- 230
- Type
- posted content
- Language
- en
- Open access
- bronze
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- Lynch-Day, M. A., Mao, K., Wang, K., Zhao, M., & Klionsky, D. J. (2012). The Role of Autophagy in Parkinson's Disease. Cold Spring Harbor Perspectives in Medicine. https://doi.org/10.1101/cshperspect.a009357
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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