Genetics of β-Amyloid Precursor Protein in Alzheimer's Disease
TCW, Julia, Goate, Alison M.·2017·Cold Spring Harbor Perspectives in Medicine
Cited by (242)
Items 201–242 of 242
- Amyloid Precursor Protein Can Cause Changes in Neuronal Firing Rates via Axon Initial SegmentDebalina Acharyya, Victoria Norman · 2023 · Journal of Neuroscience
- Identify Alzheimer’s disease subtypes and markers from multi‐omic data of human brain and blood with a subspace merging algorithmZiyan Song, Xiaoqing Huang, Asha Jacob Jannu, Travis S. Johnson, Jie Zhang, Kun Huang · 2023 · Alzheimer s & Dementia
- Lowering glucose enhances BACE1 activity and Aβ generation in mouse brain slice culturesOlivia Sheppard, Robert Humphrey, Claire S. Durrant, Michael P. Coleman · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- The Genetics of Alzheimer’s Disease and the role of non-long coding RNAs in disease pathogenesisSreekanya Roy, Sima Biswas, Dipanjan Guha, Rakhi Dasgupta, Angshuman Bagchi · 2024
- Transposable element small and long RNAs in aging brains and implications in Huntington’s and Parkinson’s diseaseGargi Dayama, Shruti Gupta, Brianne K. Connizzo, Adam Thomas Labadorf, Richard H. Myers, Nelson C. Lau · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- A bird's eye view to the homeostatic, Alzheimer and Glioblastoma attractorsNieves, Joan, Gil, Gabriel, Gonzalez, Augusto · 2025 · Heliyon
- Interactions between mild traumatic brain injury and genetics perturb neuronal and glial pathways and networks relevant to learning and memory in ABCD studyMichael Cheng, Melody Mao, Wenjing Meng, Florin Vaida, Joanna Jacobus, Emily A. Troyer, Everett L. Delfel, Emily L. Dennis, Elisabeth A. Wilde, Tracy J. Abildskov et al. · 2025 · medRxiv
- A Systems Biology Approach to Understanding Delirium Pathophysiology and Identifying Natural Compounds for Potential Therapeutic PurposesBabak Sokouti · 2025 · OBM Neurobiology
- The Flipons, Infections, and Amyloids that Foreshadow the Fading Memories of Alzheimer’s DiseaseAlan G. Herbert · 2025 · Neuroscience Insights
- PF-04691502, a PI3K/mTOR Dual Inhibitor, Ameliorates AD-like Pathology in a Mouse Model of ADMarika Lanza, Rossella Basilotta, Antonella Caccamo, Giovanna Casili, Alberto Repici, Salvatore Oddo, Emanuela Esposito · 2025 · Cells
- The Icelandic mutation APPA673T on amyloid-β plaque burden in the 5xFAD Alzheimer modelAnne Anschuetz, Renny Listyono, Thomas Vorley, Bettina Platt, Charles R. Harrington, Gernot Riedel, K. Schwab · 2025 · bioRxiv
- Autophagy and Neuroinflammatory Pathways in Alzheimer’s DiseaseRohan V. Gupta, Jogendra Singh Pawar, Lohitha Gujjari, Smita Kumari · 2025 · Springer eBooks
- Use of rodent models in drug discovery for Alzheimer’s diseaseJames E. Barrett, Joanne R. Mathiasen, Paul McGonigle · 2025 · Elsevier eBooks
- Identification of chemicals targeting dementia genes and pathways in the Comparative Toxicogenomics DatabaseScarlet M Cockell, Sean M. Harris, Rachel K. Morgan, Gary J. Patti, Erin B. Ware, Kelly M. Bakulski · 2026 · Alzheimer s & Dementia
- Microbiota and Alzheimer's disease: Toward new clinical approachesJelena Đokić, Miroslav Dinić · 2025 · Medicinski podmladak
- Neuropathological Research Developed From the Analysis of Forensic Autopsy CasesNaoki Nishida · 2025 · Pathology International
- Neuroimmune Signalling: Novel Emerging Options to Treat NeurodegenerationAshwani Sharma, Bhaskaranand Pancholi, Anjali Sharma, Debapriya Garabadu · 2026 · Springer eBooks
- In Silico Phosphoproteomic Analysis Reveals Divergent Regulation of Presenilin 1 and Presenilin 2Sadia Begum, Javier de Andrés Álvarez, Claudia Manzoni, Charles Arber, Patrick Alfryn Lewis · 2026 · NeuroMolecular Medicine
- Probing APP Cleavage and Amyloid-β Assembly via Synthetic MUC-Type O -Glycosylated APP GlycopeptidesNancy Vela, Gustavo De Nadai Mundim, Deepika Regmi, Ivet Boneva, Ramya Ayyalasomayajula, Maria E. Vezzi, Valentina Sopo Borraez, Alexis Crowder, Alejandra Coronel-Zegarra, Hasham Shafi et al. · 2026 · ACS Chemical Neuroscience
- Identification of a novel Aβ(pGlu3-x) targeting pathway in Alzheimer’s diseaseSteffen Roßner, Sarah Schrempel, Corinna Höfling, Charlotte Minister, Thomas Liepold, Marcel Naumann, Anna Katharina Kottwitz, Matti Schau, Merle Fricke, Maike Hartlage‐Rübsamen et al. · 2026 · Research Square
- Neuronal and glial networks interact with traumatic brain injury to modulate cognition in ABCD studyMichael Cheng, Melody Mao, Wenjing Meng, Joanna Jacobus, Emily A. Troyer, Everett L. Delfel, Emily L. Dennis, Elisabeth A. Wilde, Tracy J. Abildskov, Nicola L. de Souza et al. · 2026 · npj Systems Biology and Applications
- Arsenic Promotes Intracellular Aβ(1−42) Accumulation via Enhanced APP but Reduced NEP Expression, and Indirectly Stimulates Extracellular Aβ Aggregation through AChE Induction in Differentiated SH-SY5Y CellsNaphada Leelaprachakul, Daranee Visitnonthachai, Apichaya Niyomchan, Kanjanamas Maliphol, Piyajit Watcharasit, Jutamaad Satayavivad · 2026 · Biological Trace Element Research
- Studying the role of human Amyloid Precursor Protein (APP) during human cortical neurogenesisKhadijeh Shabani · 2021 · theses.fr (ABES)
- Synthesis and conformational analysis of peptidomimetic foldamers containing diaza-peptide units : application in protein-protein interactionsChenghui Shi · 2022 · theses.fr (ABES)
- Etude des mécanismes physiοpathοlοgiques de la maladie d'Alzheimer : appοrt de l'étude des variants du gène SΟRL1Romain Castelot · 2024 · theses.fr (ABES)
- Pathophysiology and Molecular Mechanisms of Alzheimer’s DiseaseSiva Sai Chandragiri, Manish Mathur, Neha Mathur · 2026 · BENTHAM SCIENCE PUBLISHERS eBooks
- Transposable element small RNAs and large RNAs in aging brains and implications in Huntington's and Parkinson's diseaseGargi Dayama, Jou-Hsuan Roxie Lee, Shruti Gupta, Christian Brion, Brianne K. Connizzo, Adam Thomas Labadorf, Richard H. Myers, Nelson C. Lau · 2026 · Genome Research
- In-vivo evaluation of neuroprotective effect of methanolic extract of Turbinaria ornatacombined with AKG against aluminium chloride-induced Alzheimer’s in Wistar ratsDeepika Kale, Ishwarya Ramachandran, Sreeja Lakshmi, Preetham Elumalai · 2026 · 3 Biotech
- Second Section: A single domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSFLiliana Napolitano · 2026 · Firenze University Press eBooks
- ReferencesLiliana Napolitano · 2026 · Firenze University Press eBooks
- DiscussionLiliana Napolitano · 2026 · Firenze University Press eBooks
- Third Section: Design of a dimeric-nanobody specific for Aβ42 oligomers: the Dimeric-DesAb-OLiliana Napolitano · 2026 · Firenze University Press eBooks
- A multidisciplinary approach for the early diagnosis of Alzheimer’s disease and potential therapeutic applicationsLiliana Napolitano · 2026 · Firenze University Press eBooks
- Material and MethodsLiliana Napolitano · 2026 · Firenze University Press eBooks
- First Section: Putative CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohortLiliana Napolitano · 2026 · Firenze University Press eBooks
- IntroductionLiliana Napolitano · 2026 · Firenze University Press eBooks
- Conclusion and Future PerspectivesLiliana Napolitano · 2026 · Firenze University Press eBooks
- The amino acid substitutions A30W, K28A, and M35C alter amyloid-β peptide toxicity in cell culture and in an in vivo model of amyloidosis in Caenorhabditis elegansDiana Patricia Quijano-Guerrero, Ana Esther Estrada-Rodríguez, Mauricio Caballero-Rodríguez, Danna Loretta de León-Rivera, Cristina Rodrı́guez-Padilla, Víctor Julián Valdés, Diana Elia Caballero-Hernández, Román Vidaltamayo, Ana Carolina Martínez‐Torres, Viviana Zomosa‐Signoret · 2026 · Frontiers in Aging Neuroscience
- The Genetics and Mechanisms of Alzheimer's Disease in Down SyndromeMichel Bourin · 2026 · Journal of Mental Health Disorders
- Alzheimer Hastalığında NHE6İrem Gülfem ALBAYRAK · 2026 · Akademisyen Kitabevi eBooks
- Potential Utilization of Natural Anthraquinone Aglycone Emodin for Alzheimer's Disease: A Comprehensive Review With Computational InsightsSalehin Sheikh, Faysal Mollah, Raihan Chowdhury, Most. Israt Jahan Oni, Mst Muslima Khatun, Md. Shadin, Md. Shimul Bhuia, Md Arshadul Hoque, Mohamed Alfaifi, Faisal H. Altemani et al. · 2026 · ChemistrySelect
- Challenges in Studying Synapses in Alzheimer's DiseaseThomas Christian Südhof · 2026 · Annals of Neurology