Genetics of β-Amyloid Precursor Protein in Alzheimer's Disease

TCW, Julia, Goate, Alison M.·2017·Cold Spring Harbor Perspectives in Medicine

Cited by (242)

Items 201–242 of 242

  1. Amyloid Precursor Protein Can Cause Changes in Neuronal Firing Rates via Axon Initial Segment
    Debalina Acharyya, Victoria Norman · 2023 · Journal of Neuroscience
  2. Identify Alzheimer’s disease subtypes and markers from multi‐omic data of human brain and blood with a subspace merging algorithm
    Ziyan Song, Xiaoqing Huang, Asha Jacob Jannu, Travis S. Johnson, Jie Zhang, Kun Huang · 2023 · Alzheimer s & Dementia
  3. Lowering glucose enhances BACE1 activity and Aβ generation in mouse brain slice cultures
    Olivia Sheppard, Robert Humphrey, Claire S. Durrant, Michael P. Coleman · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  4. The Genetics of Alzheimer’s Disease and the role of non-long coding RNAs in disease pathogenesis
    Sreekanya Roy, Sima Biswas, Dipanjan Guha, Rakhi Dasgupta, Angshuman Bagchi · 2024
  5. Transposable element small and long RNAs in aging brains and implications in Huntington’s and Parkinson’s disease
    Gargi Dayama, Shruti Gupta, Brianne K. Connizzo, Adam Thomas Labadorf, Richard H. Myers, Nelson C. Lau · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  6. A bird's eye view to the homeostatic, Alzheimer and Glioblastoma attractors
    Nieves, Joan, Gil, Gabriel, Gonzalez, Augusto · 2025 · Heliyon
  7. Interactions between mild traumatic brain injury and genetics perturb neuronal and glial pathways and networks relevant to learning and memory in ABCD study
    Michael Cheng, Melody Mao, Wenjing Meng, Florin Vaida, Joanna Jacobus, Emily A. Troyer, Everett L. Delfel, Emily L. Dennis, Elisabeth A. Wilde, Tracy J. Abildskov et al. · 2025 · medRxiv
  8. A Systems Biology Approach to Understanding Delirium Pathophysiology and Identifying Natural Compounds for Potential Therapeutic Purposes
    Babak Sokouti · 2025 · OBM Neurobiology
  9. The Flipons, Infections, and Amyloids that Foreshadow the Fading Memories of Alzheimer’s Disease
    Alan G. Herbert · 2025 · Neuroscience Insights
  10. PF-04691502, a PI3K/mTOR Dual Inhibitor, Ameliorates AD-like Pathology in a Mouse Model of AD
    Marika Lanza, Rossella Basilotta, Antonella Caccamo, Giovanna Casili, Alberto Repici, Salvatore Oddo, Emanuela Esposito · 2025 · Cells
  11. The Icelandic mutation APPA673T on amyloid-β plaque burden in the 5xFAD Alzheimer model
    Anne Anschuetz, Renny Listyono, Thomas Vorley, Bettina Platt, Charles R. Harrington, Gernot Riedel, K. Schwab · 2025 · bioRxiv
  12. Autophagy and Neuroinflammatory Pathways in Alzheimer’s Disease
    Rohan V. Gupta, Jogendra Singh Pawar, Lohitha Gujjari, Smita Kumari · 2025 · Springer eBooks
  13. Use of rodent models in drug discovery for Alzheimer’s disease
    James E. Barrett, Joanne R. Mathiasen, Paul McGonigle · 2025 · Elsevier eBooks
  14. Identification of chemicals targeting dementia genes and pathways in the Comparative Toxicogenomics Database
    Scarlet M Cockell, Sean M. Harris, Rachel K. Morgan, Gary J. Patti, Erin B. Ware, Kelly M. Bakulski · 2026 · Alzheimer s & Dementia
  15. Microbiota and Alzheimer's disease: Toward new clinical approaches
    Jelena Đokić, Miroslav Dinić · 2025 · Medicinski podmladak
  16. Neuropathological Research Developed From the Analysis of Forensic Autopsy Cases
    Naoki Nishida · 2025 · Pathology International
  17. Neuroimmune Signalling: Novel Emerging Options to Treat Neurodegeneration
    Ashwani Sharma, Bhaskaranand Pancholi, Anjali Sharma, Debapriya Garabadu · 2026 · Springer eBooks
  18. In Silico Phosphoproteomic Analysis Reveals Divergent Regulation of Presenilin 1 and Presenilin 2
    Sadia Begum, Javier de Andrés Álvarez, Claudia Manzoni, Charles Arber, Patrick Alfryn Lewis · 2026 · NeuroMolecular Medicine
  19. Probing APP Cleavage and Amyloid-β Assembly via Synthetic MUC-Type O -Glycosylated APP Glycopeptides
    Nancy Vela, Gustavo De Nadai Mundim, Deepika Regmi, Ivet Boneva, Ramya Ayyalasomayajula, Maria E. Vezzi, Valentina Sopo Borraez, Alexis Crowder, Alejandra Coronel-Zegarra, Hasham Shafi et al. · 2026 · ACS Chemical Neuroscience
  20. Identification of a novel Aβ(pGlu3-x) targeting pathway in Alzheimer’s disease
    Steffen Roßner, Sarah Schrempel, Corinna Höfling, Charlotte Minister, Thomas Liepold, Marcel Naumann, Anna Katharina Kottwitz, Matti Schau, Merle Fricke, Maike Hartlage‐Rübsamen et al. · 2026 · Research Square
  21. Neuronal and glial networks interact with traumatic brain injury to modulate cognition in ABCD study
    Michael Cheng, Melody Mao, Wenjing Meng, Joanna Jacobus, Emily A. Troyer, Everett L. Delfel, Emily L. Dennis, Elisabeth A. Wilde, Tracy J. Abildskov, Nicola L. de Souza et al. · 2026 · npj Systems Biology and Applications
  22. Arsenic Promotes Intracellular Aβ(1−42) Accumulation via Enhanced APP but Reduced NEP Expression, and Indirectly Stimulates Extracellular Aβ Aggregation through AChE Induction in Differentiated SH-SY5Y Cells
    Naphada Leelaprachakul, Daranee Visitnonthachai, Apichaya Niyomchan, Kanjanamas Maliphol, Piyajit Watcharasit, Jutamaad Satayavivad · 2026 · Biological Trace Element Research
  23. Studying the role of human Amyloid Precursor Protein (APP) during human cortical neurogenesis
    Khadijeh Shabani · 2021 · theses.fr (ABES)
  24. Synthesis and conformational analysis of peptidomimetic foldamers containing diaza-peptide units : application in protein-protein interactions
    Chenghui Shi · 2022 · theses.fr (ABES)
  25. Etude des mécanismes physiοpathοlοgiques de la maladie d'Alzheimer : appοrt de l'étude des variants du gène SΟRL1
    Romain Castelot · 2024 · theses.fr (ABES)
  26. Pathophysiology and Molecular Mechanisms of Alzheimer’s Disease
    Siva Sai Chandragiri, Manish Mathur, Neha Mathur · 2026 · BENTHAM SCIENCE PUBLISHERS eBooks
  27. Transposable element small RNAs and large RNAs in aging brains and implications in Huntington's and Parkinson's disease
    Gargi Dayama, Jou-Hsuan Roxie Lee, Shruti Gupta, Christian Brion, Brianne K. Connizzo, Adam Thomas Labadorf, Richard H. Myers, Nelson C. Lau · 2026 · Genome Research
  28. In-vivo evaluation of neuroprotective effect of methanolic extract of Turbinaria ornatacombined with AKG against aluminium chloride-induced Alzheimer’s in Wistar rats
    Deepika Kale, Ishwarya Ramachandran, Sreeja Lakshmi, Preetham Elumalai · 2026 · 3 Biotech
  29. Second Section: A single domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  30. References
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  31. Discussion
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  32. Third Section: Design of a dimeric-nanobody specific for Aβ42 oligomers: the Dimeric-DesAb-O
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  33. A multidisciplinary approach for the early diagnosis of Alzheimer’s disease and potential therapeutic applications
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  34. Material and Methods
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  35. First Section: Putative CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  36. Introduction
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  37. Conclusion and Future Perspectives
    Liliana Napolitano · 2026 · Firenze University Press eBooks
  38. The amino acid substitutions A30W, K28A, and M35C alter amyloid-β peptide toxicity in cell culture and in an in vivo model of amyloidosis in Caenorhabditis elegans
    Diana Patricia Quijano-Guerrero, Ana Esther Estrada-Rodríguez, Mauricio Caballero-Rodríguez, Danna Loretta de León-Rivera, Cristina Rodrı́guez-Padilla, Víctor Julián Valdés, Diana Elia Caballero-Hernández, Román Vidaltamayo, Ana Carolina Martínez‐Torres, Viviana Zomosa‐Signoret · 2026 · Frontiers in Aging Neuroscience
  39. The Genetics and Mechanisms of Alzheimer's Disease in Down Syndrome
    Michel Bourin · 2026 · Journal of Mental Health Disorders
  40. Alzheimer Hastalığında NHE6
    İrem Gülfem ALBAYRAK · 2026 · Akademisyen Kitabevi eBooks
  41. Potential Utilization of Natural Anthraquinone Aglycone Emodin for Alzheimer's Disease: A Comprehensive Review With Computational Insights
    Salehin Sheikh, Faysal Mollah, Raihan Chowdhury, Most. Israt Jahan Oni, Mst Muslima Khatun, Md. Shadin, Md. Shimul Bhuia, Md Arshadul Hoque, Mohamed Alfaifi, Faisal H. Altemani et al. · 2026 · ChemistrySelect
  42. Challenges in Studying Synapses in Alzheimer's Disease
    Thomas Christian Südhof · 2026 · Annals of Neurology