The Intraflagellar Transport Machinery

Taschner, Michael, Lorentzen, Esben·2016·Cold Spring Harbor Perspectives in Biology

Cited by (349)

Items 101–200 of 349

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  2. Extensive structural rearrangement of intraflagellar transport trains underpins bidirectional cargo transport
    Samuel E. Lacey, Andrea Graziadei, Gaia Pigino · 2024 · Cell
  3. IFT proteins interact with HSET to promote supernumerary centrosome clustering in mitosis
    Benjamin Vitre, Nicolas Taulet, Audrey Guesdon, Audrey Douanier, Aurelie Dosdane, Melanie Cisneros, Justine Maurin, Sabrina Hettinger, Christelle Anguille, Michael John Taschner et al. · 2020 · EMBO Reports
  4. The Enigmatic Role of Lipids in Cilia Signaling
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  5. Teasing out function from morphology: Similarities between primary cilia and immune synapses
    Tiphaine Douanne, Jane C. Stinchcombe, Gillian M. Griffiths · 2021 · The Journal of Cell Biology
  6. Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development
    John Snedeker, Elizabeth N. Schock, Jamie N. Struve, Ching‐Fang Chang, Megan Cionni, Pamela Vivian Tran, Samantha A. Brugmann, Rolf W. Stottmann · 2017 · PLoS ONE
  7. Cytoplasmic preassembly and trafficking of axonemal dyneins
    Paurav B. Desai, Anudariya B. Dean, David R. Mitchell · 2017 · Elsevier eBooks
  8. Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry
    Hantian Qiu, Sayaka Fujisawa, Shohei Nozaki, Yohei Katoh, Kazuhisa Nakayama · 2020 · Biology Open
  9. A Model for Primary Cilium Biogenesis by Polarized Epithelial Cells: Role of the Midbody Remnant and Associated Specialized Membranes
    Leticia Labat‐de‐Hoz, Armando Rubio-Ramos, Javier Casares-Arias, Miguel Bernabé‐Rubio, Isabel Correas, Miguel Angel Alonso · 2021 · Frontiers in Cell and Developmental Biology
  10. A bioactive peptide amidating enzyme is required for ciliogenesis
    Dhivya Kumar, Daniela Strenkert, Ramila Patel, Michael Troy Leonard, Sabeeha Merchant, Richard E. Mains, Stephen M. King, Betty A. Eipper · 2017 · eLife
  11. The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment
    Christin Hanke‐Gogokhia, Zhijian Wu, Ali S. Sharif, Hussein Yazigi, Jeanne M. Frederick, Wolfgang Baehr · 2017 · Journal of Biological Chemistry
  12. Reproduction Function in Male Patients With Bardet Biedl Syndrome
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  13. IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning
    Nicolas Taulet, Benjamin Vitre, Christelle Anguille, Audrey Douanier, Murielle Rocancourt, Michael John Taschner, Esben Lorentzen, Arnaud Échard, Bénédicte Delaval · 2017 · Nature Communications
  14. Formation of the B9-domain protein complex MKS1–B9D2–B9D1 is essential as a diffusion barrier for ciliary membrane proteins
    Misato Okazaki, Takuya Kobayashi, Shuhei Chiba, Ryota Takei, Luxiaoxue Liang, Kazuhisa Nakayama, Yohei Katoh · 2020 · Molecular Biology of the Cell
  15. In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip
    Jenna Lynne Wingfield, Betlehem Mekonnen, Ilaria Mengoni, Peiwei Liu, Mareike A. Jordan, Dennis Ray Diener, Gaia Pigino, Karl F. Lechtreck · 2021 · Journal of Cell Science
  16. Structure of the ciliogenesis-associated CPLANE complex
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  17. Neurodevelopmental Disease Mechanisms, Primary Cilia, and Endosomes Converge on the BLOC-1 and BORC Complexes
    Cortnie L. Hartwig, William J Monis, Xun Chen, Dion K. Dickman, G. Pazour, V. Faundez · 2017 · Developmental Neurobiology
  18. Protein turnover dynamics suggest a diffusion-to-capture mechanism for peri-basal body recruitment and retention of intraflagellar transport proteins
    Jaime V.K. Hibbard, Neftalí Vázquez, Rohit Satija, John B. Wallingford · 2021 · Molecular Biology of the Cell
  19. Mutations in DYNC2H1 , the cytoplasmic dynein 2, heavy chain 1 motor protein gene, cause short‐rib polydactyly type I, Saldino–Noonan type
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  20. Molecular basis of ciliary defects caused by compound heterozygous IFT144/WDR19 mutations found in cranioectodermal dysplasia
    Yamato Ishida, Takuya Kobayashi, Shuhei Chiba, Yohei Katoh, Kazuhisa Nakayama · 2021 · Human Molecular Genetics
  21. A homozygous deleterious CDK10 mutation in a patient with agenesis of corpus callosum, retinopathy, and deafness
    Vincent J. Guen, Simon Edvardson, Nitay Fraenkel, Aviva Fattal‐Valevski, Chaim Jalas, Irene I. Anteby, Avraham Shaag, Talia Dor, David Gillis, Eitan Kerem et al. · 2017 · American Journal of Medical Genetics Part A
  22. DYF-5/MAK–dependent phosphorylation promotes ciliary tubulin unloading
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  23. Membrane retrieval, recycling and release pathways that organise and sculpt the ciliary membrane
    Stephen P. Carter, Oliver E. Blacque · 2019 · Current Opinion in Cell Biology
  24. The Caenorhabditis elegans Tubby homolog dynamically modulates olfactory cilia membrane morphogenesis and phospholipid composition
    Danielle N. DiTirro, Alison Philbrook, Kendrick Rubino, Piali Sengupta · 2019 · eLife
  25. Testing the role of intraflagellar transport in flagellar length control using length-altering mutants of Chlamydomonas
    Kimberly A. Wemmer, William Basil Ludington, Wallace F. Marshall · 2019 · Philosophical Transactions of the Royal Society B Biological Sciences
  26. ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane
    Sayaka Fujisawa, Hantian Qiu, Shohei Nozaki, Shuhei Chiba, Yohei Katoh, Kazuhisa Nakayama · 2021 · Biology Open
  27. Regulation of hyperoxia-induced social behaviour in Pristionchus pacificus nematodes requires a novel cilia-mediated environmental input
    Eduardo Moreno, Bogdan Sieriebriennikov, Hanh Witte, Christian Rödelsperger, James W. Lightfoot, Ralf J. Sommer · 2017 · Scientific Reports
  28. Cilia drive developmental plasticity and are essential for efficient prey detection in predatory nematodes
    Eduardo Moreno, James W. Lightfoot, Maša Lenuzzi, Ralf J. Sommer · 2019 · Proceedings of the Royal Society B Biological Sciences
  29. WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System
    Yeon-Joo Kim, Soo‐Hyun Kim · 2020 · Endocrinology and Metabolism
  30. ARL3 mediates BBSome ciliary turnover by promoting its outward movement across the transition zone
    Yan‐Xia Liu, Wei-Yue Sun, Bin Xue, Rui‐Kai Zhang, Wenjuan Li, Xixian Xie, Zhen‐Chuan Fan · 2022 · The Journal of Cell Biology
  31. The Role of Centrosome Distal Appendage Proteins (DAPs) in Nephronophthisis and Ciliogenesis
    Fatma Mansour, Felix J. Boivin, Iman B. Shaheed, Markus Schueler, Kai Martin Schmidt-Ott · 2021 · International Journal of Molecular Sciences
  32. Second case of Bardet–Biedl syndrome caused by biallelic variants in IFT74
    Lotte Kleinendorst, Sanne I. M. Alsters, Ozair Abawi, Quinten Waisfisz, Elles M. J. Boon, Erica L T van den Akker, Mieke M. van Haelst · 2020 · European Journal of Human Genetics
  33. BBS Proteins Affect Ciliogenesis and Are Essential for Hedgehog Signaling, but Not for Formation of iPSC-Derived RPE-65 Expressing RPE-Like Cells
    Caroline Amalie Brunbjerg Hey, Lasse Jonsgaard Larsen, Zeynep Tümer, Karen Brøndum‐Nielsen, Karen Grønskov, Tina Duelund Hjortshøj, Lisbeth Birk Møller · 2021 · International Journal of Molecular Sciences
  34. Functional exploration of heterotrimeric kinesin-II in IFT and ciliary length control in Chlamydomonas
    Shufen Li, Wei Chen, Kirsty Y. Wan, Hui Tao, Xin Liang, Junmin Pan · 2020 · eLife
  35. Primary Ciliary Signaling in the Skin—Contribution to Wound Healing and Scarring
    Mayu Hosio, Viljar Jaks, Heli Lagus, Jyrki Vuola, Rei Ogawa, Esko M Kankuri · 2020 · Frontiers in Cell and Developmental Biology
  36. STORM imaging reveals the spatial arrangement of transition zone components and IFT particles at the ciliary base in Tetrahymena
    Khodor S. Hazime, Zhou Zhu, Ewa Joachimiak, Natalia A. Bulgakova, Dorota Włoga, Jarema J. Malicki · 2021 · Scientific Reports
  37. Direct imaging of intraflagellar-transport turnarounds reveals that motors detach, diffuse, and reattach to opposite-direction trains
    Zhiqing Zhang, Noémie Danné, Bonno Meddens, Iddo Heller, Erwin J.G. Peterman · 2021 · Proceedings of the National Academy of Sciences
  38. Nuclear roles for cilia-associated proteins
    Tristan D. McClure‐Begley, Michael W. Klymkowsky · 2017 · Cilia
  39. RPGRIP1L helps to establish the ciliary gate for entry of proteins
    Huawen Lin, Suyang Guo, Susan K. Dutcher · 2018 · Journal of Cell Science
  40. Composition, structure and function of the eukaryotic flagellum distal tip
    Jacob T. Croft, Davide Zabeo, Radhika Subramanian, Johanna Louise Höög · 2018 · Essays in Biochemistry
  41. CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins
    Deniz Conkar, Ezgi Odabasi, Jovana Deretic, Umut Batman, Kari-Anne Myrum Frikstad, Sebastian Patzke, Elif Nur Firat‐Karalar · 2023 · Journal of Cell Science
  42. Multiple interactions of the dynein-2 complex with the IFT-B complex are required for effective intraflagellar transport
    Shunya Hiyamizu, Hantian Qiu, Laura Vuolo, Nicola L. Stevenson, Caroline Shak, Kate J. Heesom, Yuki Hamada, Yuta Tsurumi, Shuhei Chiba, Yohei Katoh et al. · 2023 · Journal of Cell Science
  43. Optimal sidestepping of intraflagellar transport kinesins regulates structure and function of sensory cilia
    Chao Xie, Liuju Li, Ming Li, Wenxin Shao, Qingyu Zuo, Xiaoshuai Huang, Riwang Chen, Wei Li, Melanie Brunnbauer, Zeynep Ökten et al. · 2020 · The EMBO Journal
  44. Dynamic Changes of Brain Cilia Transcriptomes across the Human Lifespan
    Siwei Chen, Wedad Alhassen, Roudabeh Vakil Monfared, Benjamin Vachirakorntong, Surya M. Nauli, Pierre Baldi, Amal Alachkar · 2021 · International Journal of Molecular Sciences
  45. Conversion of anterograde into retrograde trains is an intrinsic property of intraflagellar transport
    Adrian P. Nievergelt, Ilia Zykov, Dennis Ray Diener, Aditya Chhatre, Tim-Oliver Buchholz, Markus Delling, Stefan Diez, Florian Jug, Ludĕk S̆tĕpánek, Gaia Pigino · 2022 · Current Biology
  46. FLS2 is a CDK-like kinase that directly binds IFT70 and is required for proper ciliary disassembly in Chlamydomonas
    Qin Zhao, Shufen Li, Shangjin Shao, Zhengmao Wang, Junmin Pan · 2020 · PLoS Genetics
  47. Structural insights into the architecture and assembly of eukaryotic flagella
    Narcis-Adrian Petriman, Esben Lorentzen · 2020 · Microbial Cell
  48. Adaptive Lipid Immiscibility and Membrane Remodeling Are Active Functional Determinants of Primary Ciliogenesis
    Miguel Bernabé‐Rubio, Minerva Bosch‐Fortea, Esther García, Jorge Bernardino de la Serna, Miguel Angel Alonso · 2020 · Small Methods
  49. Switching it up: algal insights into sexual transitions
    Susana M. Coelho, James Umen · 2021 · Plant Reproduction
  50. Transient accumulation and bidirectional movement of KIF13B in primary cilia
    Alice Dupont Juhl, Zeinab Anvarian, Stefanie Kuhns, Julia Berges, Jens Andersen, Daniel Wüstner, Lotte Bang Pedersen · 2022 · Journal of Cell Science
  51. Pharmacological Regulation of Primary Cilium Formation Affects the Mechanosensitivity of Osteocytes
    Dong Ding, Xiao Yong Yang, Huiqin Luan, Xintong Wu, Cai He, Lianwen Sun, Yubo Fan · 2020 · Calcified Tissue International
  52. Three-color single-molecule imaging reveals conformational dynamics of dynein undergoing motility
    Stefan Niekamp, Nico Stuurman, Nan Zhang, Ronald D. Vale · 2021 · Proceedings of the National Academy of Sciences
  53. Morphology and Transport in Eukaryotic Cells
    Anamika Agrawal, Zubenelgenubi C. Scott, Elena F. Koslover · 2022 · Annual Review of Biophysics
  54. Permanent cilia loss during cerebellar granule cell neurogenesis involves withdrawal of cilia maintenance and centriole capping
    Sandii Constable, Carolyn M. Ott, Andrew L. Lemire, Kevin White, Yu Xun, Amin Lim, Jennifer Lippincott‐Schwartz, Saikat Mukhopadhyay · 2024 · Proceedings of the National Academy of Sciences
  55. Using Paramecium as a Model for Ciliopathies
    Megan Smith Valentine, Judith Van Houten · 2021 · Genes
  56. Comparative Proteomics Reveals Timely Transport into Cilia of Regulators or Effectors as a Mechanism Underlying Ciliary Disassembly
    Limei Wang, Lixiao Gu, Dan Meng, Qiong Wu, Haiteng Deng, Junmin Pan · 2017 · Journal of Proteome Research
  57. Hedgehog pathway, cell cycle, and primary cilium
    Tenghan Zhuang · 2025 · Cell Death Discovery
  58. Primary cilia function as hubs for signal transduction
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  59. The Functionally Unannotated Proteome of Human Male Tissues: A Shared Resource to Uncover New Protein Functions Associated with Reproductive Biology
    Yves Vandenbrouck, Charles Pineau, Lydie Lane · 2020 · Journal of Proteome Research
  60. BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to intraflagellar transport turnaround involving ICK/CILK1
    Yuuki Satoda, Tatsuro Noguchi, Taiju Fujii, Aoi Taniguchi, Yohei Katoh, Kazuhisa Nakayama · 2022 · Molecular Biology of the Cell
  61. DAF‐19/RFX controls ciliogenesis and influences oxygen‐induced social behaviors in Pristionchus pacificus
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  62. Deciphering cilia and ciliopathies using proteomic approaches
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  63. Assembly and stability of IFT-B complex and its function in BBSome trafficking
    Jieling Wang, Xin Zhu, Zhengmao Wang, Xuecheng Li, Hui Tao, Junmin Pan · 2022 · iScience
  64. Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport
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  65. Molecular and structural perspectives on protein trafficking to the primary cilium membrane
    Vivek Reddy Palicharla, Saikat Mukhopadhyay · 2024 · Biochemical Society Transactions
  66. Intraflagellar transport 46 (IFT46) is essential for trafficking IFT proteins between cilia and cytoplasm in Paramecium
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  67. Male infertility
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  68. The Ciliary Protein IFT 57 in the Macronucleus ofParamecium
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  69. MEIG1 determines the manchette localization of IFT20 and IFT88, two intraflagellar transport components in male germ cells
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  70. The factory, the antenna and the scaffold: the three-way interplay between the Golgi, cilium and extracellular matrix underlying tissue function
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  71. SANS (USH1G) Molecularly Links the Human Usher Syndrome Protein Network to the Intraflagellar Transport Module by Direct Binding to IFT-B Proteins
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  72. Purification and crystal structure of human ODA16 : Implications for ciliary import of outer dynein arms by the intraflagellar transport machinery
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  73. Non-ciliary Roles of IFT Proteins in Cell Division and Polycystic Kidney Diseases
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  74. Large‐scale analysis reveals spatiotemporal circadian patterns of cilia transcriptomes in the primate brain
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  75. Trypanosomes have divergent kinesin-2 proteins that function differentially in flagellum biosynthesis and cell viability
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  76. Gene set predictor for post-treatment Lyme disease
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  77. Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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  78. ERICH3 in Primary Cilia Regulates Cilium Formation and the Localisations of Ciliary Transport and Sonic Hedgehog Signaling Proteins
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  79. CCRK/CDK20 regulates ciliary retrograde protein trafficking via interacting with BROMI/TBC1D32
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  80. Morphologically intact airways in lung fibrosis have an abnormal proteome
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  81. IFT25 is required for the construction of the trypanosome flagellum
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  82. The primary cilia are associated with the axon initial segment in neurons
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  83. Defective airway intraflagellar transport underlies a combined motile and primary ciliopathy syndrome caused byIFT74mutations
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  84. Functions of cilia in cardiac development and disease
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  86. Emerging Roles of the Intraflagellar Transport System in the Orchestration of Cellular Degradation Pathways
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  88. TTC30A and TTC30B Redundancy Protects IFT Complex B Integrity and Its Pivotal Role in Ciliogenesis
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  90. C11ORF74 interacts with the IFT-A complex and participates in ciliary BBSome localization
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  94. Dynein-2–driven intraciliary retrograde trafficking indirectly requires multiple interactions of IFT54 in the IFT-B complex with the dynein-2 complex
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  95. The IFT81‐IFT74 complex acts as an unconventional RabL2 GTPase‐activating protein during intraflagellar transport
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  96. NRF2 and Primary Cilia: An Emerging Partnership
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  97. Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at primary cilia and regulates ciliary length and signaling
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  98. Kinesin family member 3A inhibits the carcinogenesis of non‑small cell lung cancer and prolongs survival
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  99. Compound heterozygous IFT81 variations in a skeletal ciliopathy patient cause Bardet–Biedl syndrome-like ciliary defects
    Koshi Tasaki, Zhuang Zhou, Yamato Ishida, Yohei Katoh, Kazuhisa Nakayama · 2023 · Human Molecular Genetics
  100. The ciliopathy gene product Cep290 is required for primary cilium formation and microtubule network organization
    Elif Nur Firat‐Karalar · 2018 · TURKISH JOURNAL OF BIOLOGY