The Intraflagellar Transport Machinery

Taschner, Michael, Lorentzen, Esben·2016·Cold Spring Harbor Perspectives in Biology

Cited by (349)

Items 201–300 of 349

  1. New Vistas in the Biology of the Flagellum—Leishmania Parasites
    Scott M. Landfear · 2022 · Pathogens
  2. Flagellar length control in biflagellate eukaryotes: time-of-flight, shared pool, train traffic and cooperative phenomena
    Swayamshree Patra, Frank Jülicher, Debashish Chowdhury · 2020 · New Journal of Physics
  3. CEP19–RABL2–IFT-B axis controls BBSome-mediated ciliary GPCR export
    Zhuang Zhou, Yohei Katoh, Kazuhisa Nakayama · 2022 · Molecular Biology of the Cell
  4. Severe skeletal abnormalities caused by defects in retrograde intraflagellar transport dyneins
    Miriam Schmidts, Hannah M. Mitchison · 2017 · Elsevier eBooks
  5. Speed and Diffusion of Kinesin-2 Are Competing Limiting Factors in Flagellar Length-Control Model
    Rui Ma, Nathan L. Hendel, Wallace F. Marshall, Hongmin Qin · 2020 · Biophysical Journal
  6. Flagellar targeting of an arginine kinase requires a conserved lipidated protein intraflagellar transport (LIFT) pathway in Trypanosoma brucei
    Maneesha Pandey, Yameng Huang, Teck Kwang Lim, Qingsong Lin, Cynthia Y. He · 2020 · Journal of Biological Chemistry
  7. Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity
    Seungwoon Seo, Seong Keun Sonn, Hyae Yon Kweon, Jing Jin, Tsutomu Kume, Je Yeong Ko, Jong Hoon Park, Goo Taeg Oh · 2024 · Investigative Ophthalmology & Visual Science
  8. Proteomic analysis of Giardia lamblia and Trichomonas vaginalis flagella reveal unique post‐translational modifications in tubulin that provide clues to regulation of their motilities
    A. V. S. Sudhakar, Sathisha Kamanna, Mallikarjun Bojja, Utpal Shashikant Tatu · 2021 · PROTEOMICS
  9. Flagellar length control in biflagellate eukaryotes: time-of-flight, shared pool, train traffic and cooperative phenomena
    Patra, S., Frank Jülicher, Chowdhury, D. · 2020 · MPG.PuRe (Max Planck Society)
  10. Intraflagellar transport trains can turn around without the ciliary tip complex
    Adrian P. Nievergelt, Ilia Zykov, Dennis Ray Diener, Tim-Oliver Buchholz, Markus Delling, Stefan Diez, Florian Jug, Ludĕk S̆tĕpánek, Gaia Pigino · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  11. Cilia proteins getting to work – how do they commute from the cytoplasm to the base of cilia?
    Jaime V.K. Hibbard, Neftalí Vázquez, John B. Wallingford · 2022 · Journal of Cell Science
  12. Appearing and disappearing acts of cilia
    Shashank Arora, Mausam Rana, Ananya Sachdev, Jacinta S. D’Souza · 2023 · Journal of Biosciences
  13. Genetic Disruption of Cilia-Associated Signaling Pathways in Patients with VACTERL Association
    Jessica Ritter, Kristina Lisec, Marina Klinner, Martina Heinrich, Dietrich von Schweinitz, Roland Kappler, Jochen Hubertus · 2023 · Children
  14. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans
    Robert A. Brinzer, Alan D. Winter, Antony P. Page · 2024 · G3 Genes Genomes Genetics
  15. Delivery of intraflagellar transport proteins to the ciliary base and assembly into trains
    Aniruddha Mitra, Evangelos Gioukakis, Wouter Mul, Erwin J.G. Peterman · 2025 · Science Advances
  16. An intraflagellar transport dependent negative feedback regulates the MAPKKK DLK-1 to protect cilia from degeneration
    Yue Sun, Yishi Jin · 2023 · Proceedings of the National Academy of Sciences
  17. Primary cilia are critical for tracheoesophageal septation
    Lindsey Avery Fitzsimons, Evangelia Tasouri, Marc A. Willaredt, Daniel Stetson, Christian Gojak, Joachim Kirsch, Humphrey Gardner, Karin Gorgas, Kerry Lee Tucker · 2023 · Developmental Dynamics
  18. Leishmania mexicana pathogenicity requires flagellar assembly but not motility
    Tom Beneke, Rachel Neish, Carolina Moura Costa Catta‐Preta, James Smith, Jessica Valli, Ciaran J. McCoy, Andreia Albuquerque-Wendt, Jeremy C. Mottram, Eva Gluenz · 2025 · Virulence
  19. In situ cryo-electron tomography and subtomogram averaging of intraflagellar transport trains
    Mareike A. Jordan, Gaia Pigino · 2019 · Methods in cell biology
  20. Primary ciliary dyskinesia relative protein ZMYND10 is involved in regulating ciliary function and intraflagellar transport in Paramecium tetraurelia
    Lei Shi, Xiangyu Shen, Yuhao Chi, Yuan Shen · 2020 · European Journal of Protistology
  21. Primary cilia control cellular patterning of Meibomian glands during morphogenesis but not lipid composition
    Céline Portal, Yvonne G. Lin, Varuni Rastogi, Cornelia Peterson, Samuel C. Yiu, James William Foster, Amber Wilkerson, Igor A. Butovich, Carlo Iomini · 2023 · Communications Biology
  22. A defined tubby domain β-barrel surface region of TULP3 mediates ciliary trafficking of diverse cargoes
    Vivek Reddy Palicharla, Hemant Badgandi, Sun-Hee Hwang, Emilie Legué, Karel F. Liem, Saikat Mukhopadhyay · 2024 · Molecular Biology of the Cell
  23. Structure of Motile Cilia
    Takashi Ishikawa · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
  24. LRRK1-mediated NDEL1 phosphorylation promotes cilia disassembly via dynein-2-driven retrograde intraflagellar transport
    Hiroshi Hanafusa, Shin Kedashiro, Mako Gotoh, Ko-hei Saitoh, Hironori Inaba, Tomoki Nishioka, Kozo Kaibuchi, Masaki Inagaki, Naoki Hisamoto, Kunihiro Matsumoto · 2022 · Journal of Cell Science
  25. A cilia-mediated environmental input induces solitary behaviour in Caenorhabditis elegans and Pristionchus pacificus nematodes
    Eduardo Moreno, Ralf J. Sommer · 2018 · Nematology
  26. KLC3 Regulates Ciliary Trafficking and Cyst Progression in CILK1 Deficiency–Related Polycystic Kidney Disease
    Gyuyeong Rah, Hwayeon Cha, Joohee Kim, Jieun Song, Hyunho Kim, Yun Kyu Oh, Curie Ahn, Minyong Kang, Jong Min Kim, Kyung Hyun Yoo et al. · 2022 · Journal of the American Society of Nephrology
  27. Primary cilia integrity governs TRPV4-mediated NF-κB/COL2 signaling in osteoarthritis pathogenesis
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  28. Large deletion of Wdr19 in developing renal tubules disrupts primary ciliogenesis, leading to polycystic kidney disease in mice
    Shang-Shiuan Yu, Ellian Wang, Chih-Ying Chiang, Po-Hao Cheng, Yu‐Shan Yeh, Yingying Wu, Yuan‐Yow Chiou, Si‐Tse Jiang · 2022 · The Journal of Pathology
  29. Hyperoxia impairs intraflagellar transport and causes dysregulated metabolism with resultant decreased cilia length
    Daniella Teape, Abigail L. Peterson, Nagib Ahsan, Kimberlyn A. Ellis, Nicholas Correia, Ryan Luo, Katy Hegarty, Hongwei Yao, Phyllis A. Dennery · 2023 · American Journal of Physiology-Lung Cellular and Molecular Physiology
  30. Early prenatal diagnosis of a recurrent case of short-rib thoracic dysplasia 3 due to compound heterozygosity for variations in the DYNC2H1 gene: an “ultrasound first” approach
    Paolo Fontana, Emanuele Agolini, Dario Cocciadiferro, Laura Letizia Mazzarelli, Aniello Di Meglio, Antonio Novelli, Gioacchino Scarano, Cinzia Lombardi, Maria Ciavarella, Fortunato Lonardo · 2023 · The Journal of Maternal-Fetal & Neonatal Medicine
  31. The emerging functions of intraflagellar transport 52 in ciliary transport and ciliopathies
    Prajna Udupa, Debasish Kumar Ghosh · 2024 · Traffic
  32. Gene dosage of independent dynein arm motor preassembly factors influences cilia assembly in Chlamydomonas reinhardtii
    Gervette M. Penny, Susan K. Dutcher · 2024 · PLoS Genetics
  33. Stem cells' centrosomes: How can organelles identified 130 years ago contribute to the future of regenerative medicine?
    Andreas Goutas, Varvara Trachana · 2021 · World Journal of Stem Cells
  34. IFT52 plays an essential role in sensory cilia formation and neuronal sensory function in Drosophila
    Yanan Hou, Yingying Zhang, Yaru Wang, Zhimao Wu, Yun‐Xia Luan, Qing Wei · 2022 · Insect Science
  35. Crystal structure of tetrameric human Rabin8 GEF domain
    Melanie Vetter, Niels Boegholm, Anni Christensen, Sagar Bhogaraju, Marie B. Andersen, Anna Lorentzen, Esben Lorentzen · 2018 · Proteins Structure Function and Bioinformatics
  36. Sub-Ciliary Segregation of Two Drosophila Transient Receptor Potential Channels Begins at the Initial Stage of Their Pre-Ciliary Trafficking
    Youngtae Kwon, Jeongmi Lee, Yun Doo Chung · 2020 · Molecules and Cells
  37. Neuronal guidance behaviours: the primary cilium perspective
    Melody Atkins, Coralie Fassier, Xavier Nicol · 2025 · Frontiers in Cell and Developmental Biology
  38. Defective IFT57 underlies a novel cause of Bardet-Biedl syndrome
    Alexandra Nitoiu, Qihong Zhang, Erika Sendra Tavares, Janice Min Li, Kashif Ahmed, Kit Green-Sanderson, Mahnoor Rashid, Shahir M. Morcos, Jason T. Maynes, Eric I. Campos et al. · 2025 · Human Molecular Genetics
  39. Role of intraflagellar transport protein IFT140 in the formation and function of motile cilia in mammals
    Yi Tian Yap, Jiehong Pan, Jian Xu, Shuo Yuan, Changmin Niu, Cheng Zheng, Wei Li, Ting Zhou, Tao Li, Yong Zhang et al. · 2025 · Cellular and Molecular Life Sciences
  40. Phototropin localization and interactions regulate photophysiological processes in Chlamydomonas reinhardtii
    Sunita Sharma, Kumari Sushmita, Rajani Singh, Sibaji K. Sanyal, Suneel Kateriya · 2025 · Biochimie
  41. Hot-wiring dynein-2 establishes roles for IFT-A in retrograde train assembly and motility
    Francisco Gonçalves-Santos, Ana R. G. De-Castro, Diogo R. M. Rodrigues, Maria J. G. De-Castro, Reto Gassmann, Carla M. C. Abreu, Tiago J. Dantas · 2023 · Cell Reports
  42. ANKS1A-Deficiency Aberrantly Increases the Entry of the Protein Transport Machinery into the Ependymal Cilia
    Haeryung Lee, Jiyeon Lee, Miram Shin, Soochul Park · 2023 · Molecules and Cells
  43. Potential Therapeutic Targets for Olfactory Dysfunction in Ciliopathies Beyond Single-Gene Replacement
    Chao Xie, Jeffrey R. Martens · 2021 · Chemical Senses
  44. Label-free proteomic comparison reveals ciliary and nonciliary phenotypes of IFT-A mutants
    Janelle C. Leggere, Jaime V.K. Hibbard, Ophelia Papoulas, Chanjae Lee, Chad G. Pearson, Edward M. Marcotte, John B. Wallingford · 2024 · Molecular Biology of the Cell
  45. Kinesin-2 autoinhibition requires elbow phosphorylation
    Chen, Guanghan, Guo, Zhengyang, Zhu, Zhiwen, Xie, Shanshan, Zhou, Tianhua, Ou, Guangshuo · 2025 · eLife
  46. Quantitative proteomics reveals insights into the assembly of IFT trains and ciliary assembly
    Shangjin Shao, Yuling Chen, Haiteng Deng, Junmin Pan · 2024 · Journal of Cell Science
  47. Intraflagellar Transport (IFT) and Sperm Formation
    Yunhao Liu, Fang Yu, Opeyemi Dhikhirullahi, Ling Zhang, Zhibing Zhang · 2025 · Advances in experimental medicine and biology
  48. Control of protein and lipid composition of photoreceptor outer segments—Implications for retinal disease
    Markus Masek, Ruxandra Bachmann‐Gagescu · 2023 · Current topics in developmental biology/Current Topics in Developmental Biology
  49. Lipid raft interacting galectin 8 regulates primary ciliogenesis
    Jhan‐Jhang Syu, Chieh‐Hsiang Chang, Pei-Yu Chang, Chia‐Hsiung Liu, Chia‐Jung Yu, Tzuu‐Shuh Jou · 2023 · The FASEB Journal
  50. Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery
    Jiaolong Wang, Rune Thomas Kidmose, Niels Boegholm, Nevin K Zacharia, Mads B. Thomsen, Anni Christensen, Tara Malik, Karl F. Lechtreck, Esben Lorentzen · 2025 · Journal of Biological Chemistry
  51. β-Arrestin mediates the export of ciliary GPR161 but not Smoothened together with the BBSome and intraflagellar transport machinery
    Taiju Fujii, Norihito Murai, Shinya Aso, Hiroyuki Takatsu, Hye‐Won Shin, Yohei Katoh, Kazuhisa Nakayama · 2025 · Journal of Cell Science
  52. The physiological cargo adaptor of kinesin-2 functions as an evolutionary conserved lockpick
    Augustine Cleetus, Georg Merck, Felix Mueller‐Planitz, Zeynep Ökten · 2022 · Proceedings of the National Academy of Sciences
  53. The distal central pair segment is structurally specialised and contributes to IFT turnaround and assembly of the tip capping structures in Chlamydomonas flagella
    Ambra Pratelli, Dalia Corbo, Pietro Lupetti, Caterina Mencarelli · 2022 · Biology of the Cell
  54. FAZ assembly in bloodstream form Trypanosoma brucei requires kinesin KIN-E
    Anna Albisetti, Robert L. Douglas, Matthew D. Welch · 2023 · Molecular Biology of the Cell
  55. Whole genome assessment of a declining game bird reveals cryptic genetic structure and insights for population management
    Leilton Willians Luna, Lisa M. Williams, Kenneth Duren, Reina M. Tyl, David P. L. Toews, Julian D. Avery · 2023 · Molecular Ecology
  56. Affinity Purification of Intraflagellar Transport (IFT) Proteins in Mice Using Endogenous Streptavidin/FLAG Tags
    Tina Beyer, Tiago Martins, Jeshmi Jeyabalan, Marian Seda, Emma Peskett, Franziska Klose, Katrin Junger, Philip L. Beales, Marius Ueffing, Karsten Boldt et al. · 2023 · Methods in molecular biology
  57. Paralog-specific TTC30 regulation of Sonic hedgehog signaling
    F. Hoffmann, Sylvia Bolz, Katrin Junger, Franziska Klose, Isabel F. Stehle, Marius Ueffing, Karsten Boldt, Tina Beyer · 2023 · Frontiers in Molecular Biosciences
  58. Distribution and bulk flow analyses of the intraflagellar transport ( IFT) motor kinesin‐2 support an “on‐demand” model for Chlamydomonas ciliary length control
    Mansi B. Patel, Paul J. Griffin, Spencer F. Olson, Jin Dai, Yuqing Hou, Tara Malik, Poulomi Das, Gui Zhang, Winston Zhao, George B. Witman et al. · 2024 · Cytoskeleton
  59. Mutually independent and cilia-independent assembly of IFT-A and IFT-B complexes at mother centriole
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  60. Chlamydomonas FBB18 is a ubiquitin-like protein essential for the cytoplasmic preassembly of various ciliary dyneins
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  61. Chlamydomonas: Cilia and Ciliopathies
    Dan Meng, Junmin Pan · 2017 · Microbiology monographs
  62. New perspectives on GPCRs: GPCR heterodimer formation (melanocortin receptor) and GPCR on primary cilia (melanin concentrating hormone receptor)
    Yuki Kobayashi · 2020 · General and Comparative Endocrinology
  63. Chronic venous insufficiency. Preventing leg ulcers is primary goal.
    Teresa J. Kelechi, Barbara J. Edlund · 2005 · PubMed
  64. Phototropin localization and interactions regulates photophysiological processes in Chlamydomonas reinhardtii
    Sunita Sharma, Kumari Sushmita, Rajani Singh, Sibaji K. Sanyal, Suneel Kateriya · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  65. Architecture of RabL2‐associated complexes at the ciliary base: A structural modeling perspective
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  66. Embryonic Lethality, Juvenile Growth Variation, and Adult Sterility Correlate With Phylogenetic Distance of Danionin Hybrids
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  67. Analysis of Caveolin in Primary Cilia
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  68. Evolutionary trajectory for nuclear functions of ciliary transport complex proteins
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  69. The role of cilia in the development, survival, and regeneration of hair cells
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  71. IFT88-KAP interaction defines a conserved mechanism for kinesin-2-IFT coupling
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  72. A WDR35-dependent coatomer transports ciliary membrane proteins from the Golgi to the cilia
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  73. CCDC66 regulates primary cilium length and signaling competence via multi-site interactions with transition zone and axonemal proteins
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  74. Cilia and Flagella
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  75. Biochemically validated structural model of the 15-subunit IFT-B complex
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  76. Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling
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  77. Evidence for intraflagellar transport in butterfly spermatocyte cilia
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  78. Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling
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  79. Immunomodulatory potential of primary cilia in the skin
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  80. TTBK2 affects sperm quality by regulating the expression of centrosomal proteins and flagellar transporters during spermiogenesis in mice
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  82. Structure Makes a Difference: IFT Complex in Ciliary Function and Ciliopathy
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  88. Dynein tails: how to hitch a ride on an IFT train
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  92. RAB18 Orchestrates Signaling Protein Ciliary Homeostasis by Facilitating BBSome Diffusion through the Transition Zone for Ciliary Entry
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