The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Trp-dependent auxin biosynthesis in Arabidopsis: involvement of cytochrome P450s CYP79B2 and CYP79B3
Open accessAbstract
The plant hormone auxin regulates many aspects of plant growth and development. Although several auxin biosynthetic pathways have been proposed, none of these pathways has been precisely defined at the molecular level. Here we provide in planta evidence that the two Arabidopsis cytochrome P450s, CYP79B2 and CYP79B3, which convert tryptophan (Trp) to indole-3-acetaldoxime (IAOx) in vitro, are critical enzymes in auxin biosynthesis in vivo. IAOx is thus implicated as an important intermediate in auxin biosynthesis. Plants overexpressing CYP79B2 contain elevated levels of free auxin and display auxin overproduction phenotypes. Conversely, cyp79B2 cyp79B3 double mutants have reduced levels of IAA and show growth defects consistent with partial auxin deficiency. Together with previous work on YUCCA, a flavin monooxygenase also implicated in IAOx production, and nitrilases that convert indole-3-acetonitrile to auxin, this work provides a framework for further dissecting auxin biosynthetic pathways and their regulation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Sites and homeostatic control of auxin biosynthesis in Arabidopsis during vegetative growth
Ljung, K., Bhalerao, R. P., & Sandberg, G. (2001) · The Plant Journal · doi:10.1046/j.1365-313x.2001.01173.x · Cited by 653
Cited by
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response
Clay, N. K., Adio, A. M., Denoux, C., Jander, G., & Ausubel, F. M. (2009) · Science · doi:10.1126/science.1164627 · Cited by 1,098
Won, C., Shen, X., Mashiguchi, K., Zheng, Z., Dai, X., Cheng, Y., Kasahara, H., Kamiya, Y., Chory, J., & Zhao, Y. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1108436108 · Cited by 641
Self-citationAuxin biosynthesis and storage forms
Korasick, D. A., Enders, T. A., & Strader, L. C. (2013) · Journal of Experimental Botany · doi:10.1093/jxb/ert080 · Cited by 533
AUXIN RESPONSE FACTOR 2 (ARF2): a pleiotropic developmental regulator
Okushima, Y., Mitina, I., Quach, H. L., & Theologis, A. (2005) · The Plant Journal · doi:10.1111/j.1365-313x.2005.02426.x · Cited by 398
Hormonal regulation of temperature‐induced growth in Arabidopsis
Stavang, J. A., Gallego‐Bartolomé, J., Gómez, M. D., Yoshida, S., Asami, T., Olsen, J. E., García‐Martínez, J. L., Alabadí, D., & Blázquez, M. A. (2009) · The Plant Journal · doi:10.1111/j.1365-313x.2009.03983.x · Cited by 331
Metadata
- Authors
- Zhao, Y., Hull, A. K., Gupta, N. R., Goss, K. A., Alonso, J., Ecker, J. R., Normanly, J., Chory, J., & Celenza, J. L.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2002-12-01
- Volume
- 16
- Issue
- 23
- Pages
- 3100-3112
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2170966566
- Cited by
- 653
- References
- 1
- Type
- posted content
- Language
- en
- Open access
- diamond
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Trp-dependent auxin biosynthesis in Arabidopsis: involvement of cytochrome P450s CYP79B2 and CYP79B3. https://app.cochat.ai/papers/10.1101/gad.1035402
- The paper
- Zhao, Y., Hull, A. K., Gupta, N. R., Goss, K. A., Alonso, J., Ecker, J. R., Normanly, J., Chory, J., & Celenza, J. L. (2002). Trp-dependent auxin biosynthesis in Arabidopsis: involvement of cytochrome P450s CYP79B2 and CYP79B3. Genes & Development. https://doi.org/10.1101/gad.1035402
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
