The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
tRNA transfers to the limelight
Open accessAbstract
tRNA has a central role in biology as the adaptor between mRNA and protein, in which anticodon interactions with the mRNA codon at one end of the L-shaped tRNA allow an attached amino acid at the other end of the tRNA to condense with the peptide chain on a second tRNA through the action of the ribosome. This familiar role of tRNA requires mature tRNAs to be recognized by the aminoacyl tRNA synthetase to add the amino acid to its 3 end, by EF1 to form a ternary complex with the aminoacylated tRNA and GTP, and by elements of the ribosome and associated components to allow binding, peptide synthesis, and translocation. Before fulfilling this role, all tRNA transcripts have to be extensively processed. Maturation of tRNAs requires five major steps: (1) removal of the 5 leader by RNase P,
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Cites
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
Calfon, M., Zeng, H., Urano, F., Till, J. H., Hubbard, S. R., Harding, H. P., Clark, S. G., & Ron, D. (2002) · Nature · doi:10.1038/415092a · Cited by 2,820
Transport Between the Cell Nucleus and the Cytoplasm
Görlich, D., & Kutay, U. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.607 · Cited by 2,022
Compilation of tRNA sequences and sequences of tRNA genes
Sprinzl, M. (2004) · Nucleic Acids Research · doi:10.1093/nar/gki012 · Cited by 1,914
An extensive network of coupling among gene expression machines
Maniatis, T., & Reed, R. (2002) · Nature · doi:10.1038/416499a · Cited by 1,146
Sidrauski, C., & Walter, P. (1997) · Cell · doi:10.1016/s0092-8674(00)80369-4 · Cited by 899
Compilation of tRNA sequences and sequences of tRNA genes
Sprinzl, M. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.1.148 · Cited by 735
Site-Specific Pseudouridine Formation in Preribosomal RNA Is Guided by Small Nucleolar RNAs
Ganot, P., Bortolin, M.-L., & Kiss, T. (1997) · Cell · doi:10.1016/s0092-8674(00)80263-9 · Cited by 641
Evidence for a Pioneer Round of mRNA Translation
Ishigaki, Y., Li, X., Serin, G., & Maquat, L. E. (2001) · Cell · doi:10.1016/s0092-8674(01)00475-5 · Cited by 582
Improvement of reading frame maintenance is a common function for several tRNA modifications
Urbonavicius, J. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.4863 · Cited by 499
tRNA Ligase Is Required for Regulated mRNA Splicing in the Unfolded Protein Response
Sidrauski, C., Cox, J. S., & Walter, P. (1996) · Cell · doi:10.1016/s0092-8674(00)81361-6 · Cited by 443
Cited by
A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)
Lee, Y. S., Shibata, Y., Malhotra, A., & Dutta, A. (2009) · Genes & Development · doi:10.1101/gad.1837609 · Cited by 1,173
3′ End Processing of a Long Nuclear-Retained Noncoding RNA Yields a tRNA-like Cytoplasmic RNA
Wilusz, J. E., Freier, S. M., & Spector, D. L. (2008) · Cell · doi:10.1016/j.cell.2008.10.012 · Cited by 720
An early step in wobble uridine tRNA modification requires the Elongator complex
HUANG, B., JOHANSSON, M. J. O., & BYSTRÖM, A. S. (2005) · RNA · doi:10.1261/rna.7247705 · Cited by 434
Natural history of S-adenosylmethionine-binding proteins
Kozbial, P. Z., & Mushegian, A. R. (2005) · BMC Structural Biology · doi:10.1186/1472-6807-5-19 · Cited by 297
Noncoding RNAs in DNA Repair and Genome Integrity
Wan, G., Liu, Y., Han, C., Zhang, X., & Lu, X. (2014) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5514 · Cited by 50
Metadata
- Authors
- Hopper, A. K., & Phizicky, E. M.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2003-01-15
- Volume
- 17
- Issue
- 2
- Pages
- 162-180
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2128098883
- Cited by
- 317
- References
- 115
- Type
- posted content
- Language
- en
- Open access
- diamond
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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