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The Arabidopsis GAI gene defines a signaling pathway that negatively regulates gibberellin responses

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Peng, Jinrong, Carol, Pierre, Richards, Donald E., King, Kathryn E., Cowling, Rachel J., Murphy, George P., Harberd, Nicholas P.·1997·Genes & Development
DOI 10.1101/gad.11.23.3194
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Abstract

The Arabidopsis gai mutant allele confers a reduction in gibberellin (GA) responsiveness. Here we report the molecular cloning of GAI and a closely related gene GRS. The predicted GAI (wild-type) and gai (mutant) proteins differ only by the deletion of a 17-amino-acid segment from within the amino-terminal region. GAI and GRS contain nuclear localization signals, a region of homology to a putative transcription factor, and motifs characteristic of transcriptional coactivators. Genetic analysis indicates that GAI is a repressor of GA responses, that GA can release this repression, and that gai is a mutant repressor that is relatively resistant to the effects of GA. Mutations at SPY and GAR2 suppress the gai phenotype, indicating the involvement of GAI, SPY, and GAR2 in a signaling pathway that regulates GA responses negatively. The existence of this pathway suggests that GA modulates plant growth through derepression rather than through simple stimulation.

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Research works printed but not linked: 64

  1. 10.1016/0168-9525(92)90263-4 · DOI
  2. Balcells, 1991, Transposons as tools for the isolation of plant genes., Trends Biotechnol., 9, 31, 10.1016/0167-7799(91)90009-7 · DOI
  3. Bancroft, 1993, Transposition pattern of the maize element Ds in Arabidopsis thaliana., Genetics, 134, 1221, 10.1093/genetics/134.4.1221 · DOI
  4. 10.1126/science.241.4869.1086 · DOI · Paper page
  5. 10.1046/j.1365-313X.1995.7030441.x · DOI
  6. 10.1038/ng0893-332 · DOI · Paper page
  7. 10.1002/jcb.240550106 · DOI
  8. Brian, 1957, The effects of some microbial metabolic products on plant growth., Symp. Soc. Exp. Biol., 11, 166
  9. Carol, 1995, Isolation and preliminary characterization of gas1-1, a mutation causing partial suppression of the phenotype conferred by the gibberellin-insensitive (gai) mutation in Arabidopsis thaliana (L.) Heyhn., Planta, 197, 414, 10.1007/BF00202665 · DOI
  10. 10.1007/BF00402888 · DOI
  11. 10.1126/science.8211181 · DOI · Paper page
  12. 10.1105/tpc.7.2.195 · DOI · Paper page
  13. 10.1104/pp.94.1.194 · DOI
  14. Davis, 1991, Chemical regulation of vegetative growth., Crit. Rev. Plant Sci., 10, 151, 10.1080/07352689109382310 · DOI
  15. 10.1016/0968-0004(91)90184-W · DOI · Paper page
  16. 10.1073/pnas.85.23.9031 · DOI
  17. 10.1038/hdy.1975.48 · DOI
  18. Gale M.D. Youssefian S. (1985) Dwarfing genes in wheat. in Progress in plant breeding, ed Russell G.E. (Butterworths, London, UK), pp 1–35. · DOI · Paper page
  19. Gilroy, 1994, Perception of gibberellin and abscisic acid at the external face of the plasma membrane of barley (Hordeum vulgare L.) aleurone protoplasts., Plant Physiol., 104, 1185, 10.1104/pp.104.4.1185 · DOI
  20. Grossi, 1995, Characterization of two barley genes that respond rapidly to dehydration stress., Plant Sci., 105, 71, 10.1016/0168-9452(94)04043-G · DOI
  21. Harberd, 1989, Genetics of dominant gibberellin-insensitive dwarfism in maize., Genetics, 121, 827, 10.1093/genetics/121.4.827 · DOI
  22. 10.1007/BF02266949 · DOI · Paper page
  23. 10.1007/BF00016489 · DOI · Paper page
  24. 10.1007/BF01102428 · DOI
  25. 10.1126/science.7569898 · DOI · Paper page
  26. Jacobsen J.V. Gubler F. Chandler P.M. (1995) Gibberellin action in germinated cereal grains. in Plant hormones: Physiology, biochemistry and molecular biology, ed Davies P.J. (Kluwer Academic Publishers, Dordrecht, The Netherlands), pp 246–271. · DOI
  27. 10.1105/tpc.5.8.887 · DOI · Paper page
  28. 10.1073/pnas.93.17.9292 · DOI · Paper page
  29. 10.1016/S0014-5793(97)00293-7 · DOI
  30. 10.1126/science.7973631 · DOI · Paper page
  31. Kieber, 1993, CTR1, a negative regulator of the ethylene response pathway in Arabidopsis, encodes a member of the Raf family of protein kinases., Cell, 72, 1, 10.1016/0092-8674(93)90119-B · DOI · Paper page
  32. 10.1007/BF00265176 · DOI · Paper page
  33. 10.1111/j.1399-3054.1985.tb02355.x · DOI · Paper page
  34. 10.1074/jbc.272.14.9308 · DOI · Paper page
  35. 10.1093/nar/23.10.1647 · DOI
  36. 10.1007/BF00402887 · DOI
  37. Lenton J.R. Hedden P. Gale M.D. (1987) Gibberellin insensitivity and depletion in wheat—consequences for development. in Hormone action in plant development: A critical appraisal, eds Hoad G.V. Lenton J.R. Jackson M.B. Atkin R.K. (Butterworths, London, UK), pp 145–160. · DOI
  38. 10.1073/pnas.90.21.10370 · DOI
  39. 10.1074/jbc.272.14.9316 · DOI · Paper page
  40. 10.1016/S0092-8674(00)80256-1 · DOI · Paper page
  41. 10.1016/S0888-7543(05)80111-9 · DOI · Paper page
  42. 10.1105/tpc.5.3.351 · DOI
  43. 10.1104/pp.113.4.1051 · DOI
  44. 10.1104/pp.108.3.1049 · DOI · Paper page
  45. 10.1111/j.1399-3054.1985.tb02310.x · DOI
  46. Putterill, 1993, Chromosome walking with YAC clones in Arabidopsis: Isolation of 1700 kb of contiguous DNA on chromosome 5, including a 300-kb region containing the flowering-time gene CO., Mol. Gen. Genet., 239, 145, 10.1007/BF00281613 · DOI
  47. 10.1016/0092-8674(95)90288-0 · DOI · Paper page
  48. 10.1104/pp.100.4.1627 · DOI
  49. 10.1016/0092-8674(91)90245-T · DOI · Paper page
  50. 10.1016/0092-8674(93)90537-Z · DOI
  51. 10.1074/jbc.272.9.5838 · DOI
  52. Ross, 1994, Recent advances in the study of gibberellin mutants., Plant Growth Regul., 15, 193, 10.1007/BF00029892 · DOI
  53. 10.1126/science.270.5243.1809 · DOI · Paper page
  54. 10.1016/0031-9422(93)85389-9 · DOI
  55. 10.1105/tpc.6.10.1509 · DOI · Paper page
  56. Swain, 1996, Genetic analysis of gibberellin signal transduction., Plant Physiol., 112, 11, 10.1104/pp.112.1.11 · DOI
  57. 10.1073/pnas.87.20.7983 · DOI
  58. 10.1007/BF02341024 · DOI
  59. 10.1038/42652 · DOI · Paper page
  60. 10.1105/tpc.5.7.757 · DOI · Paper page
  61. Wilson, 1995, Phenotypic suppression of the gibberellin-insensitive mutant (gai) of Arabidopsis., Plant Physiol., 108, 495, 10.1104/pp.108.2.495 · DOI
  62. 10.1104/pp.100.1.403 · DOI · Paper page
  63. Winkler, 1994, Physiological genetics of the dominant gibberellin-nonresponsive maize dwarfs, Dwarf8 and Dwarf9., Planta, 193, 341, 10.1007/BF00201811 · DOI
  64. 10.1073/pnas.92.14.6640 · DOI

Cited by

Metadata

Authors
Peng, J., Carol, P., Richards, D. E., King, K. E., Cowling, R. J., Murphy, G. P., & Harberd, N. P.
Venue
Genes & Development
Publisher
Cold Spring Harbor Laboratory
Published
1997-12-01
Volume
11
Issue
23
Pages
3194-3205
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
DOI
10.1101/gad.11.23.3194
OpenAlex
W1978678736
Cited by
1,153
References
5
Type
posted content
Language
en
Open access
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