The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1
Open accessAbstract
Response to the gaseous plant hormone ethylene in Arabidopsis requires the EIN3/EIL family of nuclear proteins. The biochemical function(s) of EIN3/EIL proteins, however, has remained unknown. In this study, we show that EIN3 and EILs comprise a family of novel sequence-specific DNA-binding proteins that regulate gene expression by binding directly to a primary ethylene response element (PERE) related to the tomato E4-element. Moreover, we identified an immediate target of EIN3,ETHYLENE-RESPONSE-FACTOR1 (ERF1), which contains this element in its promoter. EIN3 is necessary and sufficient for ERF1 expression, and, like EIN3-overexpression in transgenic plants, constitutive expression of ERF1 results in the activation of a variety of ethylene response genes and phenotypes. Evidence is also provided that ERF1 acts downstream of EIN3 and all other components of the ethylene signaling pathway. The results demonstrate that the nuclear proteins EIN3 and ERF1 act sequentially in a cascade of transcriptional regulation initiated by ethylene gas.
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Cites
Stockinger, E. J., Gilmour, S. J., & Thomashow, M. F. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.3.1035 · Cited by 1,807
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Chaves, M. M., Maroco, J. P., & Pereira, J. S. (2003) · Functional Plant Biology · doi:10.1071/fp02076 · Cited by 3,845
Sakuma, Y., Liu, Q., Dubouzet, J. G., Abe, H., Shinozaki, K., & Yamaguchi-Shinozaki, K. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.6299 · Cited by 1,993
EIN2, a Bifunctional Transducer of Ethylene and Stress Responses in Arabidopsis
Alonso, J. M., Hirayama, T., Roman, G., Nourizadeh, S., & Ecker, J. R. (1999) · Science · doi:10.1126/science.284.5423.2148 · Cited by 1,312
Self-citationLicausi, F., Ohme‐Takagi, M., & Perata, P. (2013) · New Phytologist · doi:10.1111/nph.12291 · Cited by 1,020
Recent advances and emerging trends in plant hormone signalling
Santner, A., & Estelle, M. (2009) · Nature · doi:10.1038/nature08122 · Cited by 960
Metadata
- Authors
- Solano, R., Stepanova, A., Chao, Q., & Ecker, J. R.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1998-12-01
- Volume
- 12
- Issue
- 23
- Pages
- 3703-3714
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W1981546231
- Cited by
- 1,287
- References
- 1
- Type
- posted content
- Language
- en
- Open access
- diamond
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- CoChat. (2026). Citation check: Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1. https://app.cochat.ai/papers/10.1101/gad.12.23.3703
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- Solano, R., Stepanova, A., Chao, Q., & Ecker, J. R. (1998). Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1. Genes & Development. https://doi.org/10.1101/gad.12.23.3703
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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