The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
EIN2, a Bifunctional Transducer of Ethylene and Stress Responses in Arabidopsis
Abstract
Ethylene regulates plant growth, development, and responsiveness to a variety of stresses. Cloning of the Arabidopsis EIN2 gene identifies a central component of the ethylene signaling pathway. The amino-terminal integral membrane domain of EIN2 shows similarity to the disease-related Nramp family of metal-ion transporters. Expression of the EIN2 CEND is sufficient to constitutively activate ethylene responses and restores responsiveness to jasmonic acid and paraquat-induced oxygen radicals to mutant plants. EIN2 is thus recognized as a molecular link between previously distinct hormone response pathways. Plants may use a combinatorial mechanism for assessing various stresses by enlisting a common set of signaling molecules.
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Cites
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., & Hediger, M. A. (1997) · Nature · doi:10.1038/41343 · Cited by 3,166
Kieber, J. J., Rothenberg, M., Roman, G., Feldmann, K. A., & Ecker, J. R. (1993) · Cell · doi:10.1016/0092-8674(93)90119-b · Cited by 1,923
Self-citationExploiting the triple response of Arabidopsis to identify ethylene-related mutants.
Guzmán, P., & Ecker, J. R. (1990) · The Plant Cell · doi:10.1105/tpc.2.6.513 · Cited by 1,294
Self-citationSolano, R., Stepanova, A., Chao, Q., & Ecker, J. R. (1998) · Genes & Development · doi:10.1101/gad.12.23.3703 · Cited by 1,287
Self-citationCoiled coils: new structures and new functions
LUPAS, A. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)10052-9 · Cited by 1,183
A two-component system that regulates an osmosensing MAP kinase cascade in yeast
Maeda, T., Wurgler-Murphy, S. M., & Saito, H. (1994) · Nature · doi:10.1038/369242a0 · Cited by 1,076
Ethylene Responses Are Negatively Regulated by a Receptor Gene Family in Arabidopsis thaliana
Hua, J., & Meyerowitz, E. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81425-7 · Cited by 1,055
Chao, Q., Rothenberg, M., Solano, R., Roman, G., Terzaghi, W., & Ecker, J. R. (1997) · Cell · doi:10.1016/s0092-8674(00)80300-1 · Cited by 1,043
Self-citationPenninckx, I. A. M. A., Thomma, B. P. H. J., Buchala, A., Métraux, J.-P., & Broekaert, W. F. (1998) · The Plant Cell · doi:10.1105/tpc.10.12.2103 · Cited by 1,037
Cited by
Molecular mechanisms of plant metal tolerance and homeostasis
Clemens, S. (2001) · Planta · doi:10.1007/s004250000458 · Cited by 1,417
Bacterial Volatiles Induce Systemic Resistance in Arabidopsis
Ryu, C.-M., Farag, M. A., Hu, C.-H., Reddy, M. S., Kloepper, J. W., & Paré, P. W. (2004) · PLANT PHYSIOLOGY · doi:10.1104/pp.103.026583 · Cited by 1,308
Phylogenetic Relationships within Cation Transporter Families of Arabidopsis
Mäser, P., Thomine, S., Schroeder, J. I., Ward, J. M., Hirschi, K., Sze, H., Talke, I. N., Amtmann, A., Maathuis, F. J. M., Sanders, D., et al. (2001) · Plant Physiology · doi:10.1104/pp.126.4.1646 · Cited by 1,257
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response
Clay, N. K., Adio, A. M., Denoux, C., Jander, G., & Ausubel, F. M. (2009) · Science · doi:10.1126/science.1164627 · Cited by 1,098
Involvement of NRAMP1 from Arabidopsis thaliana in iron transport
Curie, C., Alonso, J. M., Jean, M. L., Ecker, J. R., & Briat, J. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3470749 · Cited by 555
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Metadata
- Authors
- Alonso, J. M., Hirayama, T., Roman, G., Nourizadeh, S., & Ecker, J. R.
- Venue
- Science
- Published
- 1999-06-25
- Volume
- 284
- Issue
- 5423
- Pages
- 2148-2152
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2084271013
- Cited by
- 1,312
- References
- 34
- FWCI
- 46.50
- Type
- journal article
- Language
- en
- Open access
- closed
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- Alonso, J. M., Hirayama, T., Roman, G., Nourizadeh, S., & Ecker, J. R. (1999). EIN2, a Bifunctional Transducer of Ethylene and Stress Responses in Arabidopsis. Science. https://doi.org/10.1126/science.284.5423.2148
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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