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Histone variants: deviants?

Open access
Kamakaka, Rohinton T., Biggins, Sue·2005·Genes & Development

Abstract

Histones are a major component of chromatin, the protein-DNA complex fundamental to genome packaging, function, and regulation. A fraction of histones are nonallelic variants that have specific expression, localization, and species-distribution patterns. Here we discuss recent progress in understanding how histone variants lead to changes in chromatin structure and dynamics to carry out specific functions. In addition, we review histone variant assembly into chromatin, the structure of the variant chromatin, and post-translational modifications that occur on the variants.

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Metadata

Authors
Kamakaka, R. T., & Biggins, S.
Venue
Genes & Development
Published
2005-02-01
Volume
19
Issue
3
Pages
295-316
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W2145924925
Cited by
374
References
2
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: Histone variants: deviants? https://app.cochat.ai/papers/10.1101/gad.1272805
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Kamakaka, R. T., & Biggins, S. (2005). Histone variants: deviants? Genes & Development. https://doi.org/10.1101/gad.1272805

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