The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair
Open accessAbstract
The failure of cells to repair damaged DNA can result in genomic instability and cancer. To efficiently repair chromosomal DNA lesions, the repair machinery must gain access to the damaged DNA in the context of chromatin. Here we report that both the RSC and Swi/Snf ATP-dependent chromatin-remodeling complexes play key roles in double-strand break (DSB) repair, specifically by homologous recombination (HR). RSC and Swi/Snf are each recruited to an in vivo DSB site but with distinct kinetics. We show that Swi/Snf is required earlier, at or preceding the strand invasion step of HR, while RSC is required following synapsis for completion of the recombinational repair event.
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Cites
DNA end-joining: from yeast to man
Critchlow, S. E., & Jackson, S. P. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01284-5 · Cited by 584
Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae
Sudarsanam, P., Iyer, V. R., Brown, P. O., & Winston, F. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3364 · Cited by 389
Genes required for ionizing radiation resistance in yeast
Bennett, C. B., Lewis, L. K., Karthikeyan, G., Lobachev, K. S., Jin, Y. H., Sterling, J. F., Snipe, J. R., & Resnick, M. A. (2001) · Nature Genetics · doi:10.1038/ng778 · Cited by 328
Recombination factors of Saccharomyces cerevisiae
Sung, P., Trujillo, K. M., & Van Komen, S. (2000) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/s0027-5107(00)00054-3 · Cited by 180
Cited by
The Biology of Chromatin Remodeling Complexes
Clapier, C. R., & Cairns, B. R. (2009) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.062706.153223 · Cited by 2,380
Self-citationDynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
Polo, S. E., & Jackson, S. P. (2011) · Genes & Development · doi:10.1101/gad.2021311 · Cited by 1,092
Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae
Tsukuda, T., Fleming, A. B., Nickoloff, J. A., & Osley, M. A. (2005) · Nature · doi:10.1038/nature04148 · Cited by 425
The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer
Hodges, C., Kirkland, J. G., & Crabtree, G. R. (2016) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a026930 · Cited by 414
Williams, R. S., Williams, J. S., & Tainer, J. A. (2007) · Biochemistry and Cell Biology · doi:10.1139/o07-069 · Cited by 399
Metadata
- Authors
- Chai, B., Huang, J., Cairns, B. R., & Laurent, B. C.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2005-07-15
- Volume
- 19
- Issue
- 14
- Pages
- 1656-1661
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2019025864
- Cited by
- 294
- References
- 4
- Type
- posted content
- Language
- en
- Open access
- diamond
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- Chai, B., Huang, J., Cairns, B. R., & Laurent, B. C. (2005). Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair. Genes & Development. https://doi.org/10.1101/gad.1273105
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