The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.

Cited by (964)

Items 601–700 of 964

1. Irofulven induces replication-dependent CHK2 activation related to p53 status
   Yutian Wang, Timothy D. Wiltshire, Jamie Senft, Eddie Reed, Weixin Wang · 2006 · Biochemical Pharmacology
2. Transcriptome Analysis of CHO Cell Size Increase During a Fed-Batch Process
   Pan, Xiao, Alsayyari, Abdulaziz A., Dalm, Ciska, Hageman, Jos A., Wijffels, René H., Martens, Dirk E. · 2019 · Biotechnology Journal
3. p53-Dependent Cytoprotective Mechanisms behind Resistance to Chemo-Radiotherapeutic Agents Used in Cancer Treatment
   Jayaraman Krishnaraj, Tatsuki Yamamoto, Rieko Ohki · 2023 · Cancers
4. Constitutive and induced functions of the p53 gene
   Andrei O. Zheltukhin, Peter M. Chumakov · 2010 · Biochemistry (Moscow)
5. DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation
   Chris Allen, Walter Tinganelli, Neelam Sharma, Jingyi Nie, Cory Sicard, Francesco Natale, Maurice King, Steve Keysar, Antonio Jimeno, Yoshiya Furusawa et al. · 2015 · Frontiers in Oncology
6. Antitumor Activity of a 5-Hydroxy-1H-Pyrrol-2-(5H)-One-Based Synthetic Small Molecule In Vitro and In Vivo
   Yunyun Geng, Xiaojian Wang, Luo Yang, Haili Sun, Yongqiang Wang, Yue Zhao, Ruiping She, Mei‐Xiang Wang, De‐Xian Wang, Jun Tang · 2015 · PLoS ONE
7. The phenotype of MDM2 auto-degradation after DNA damage is due to epitope masking by phosphorylation
   Cheng, Qian, Chen, Jiandong · 2011 · Cell Cycle
8. Dynamic O-GlcNAcylation coordinates etoposide-triggered tumor cell pyroptosis by regulating p53 stability
   Jing Wang, Yida Wang, Huan Xiao, Wanyi Yang, Weibo Zuo, Ziming You, Chuanfang Wu, Jinku Bao · 2024 · Journal of Biological Chemistry
9. Post-Translational Modifications of p53 in Ferroptosis: Novel Pharmacological Targets for Cancer Therapy
   Le Zhang, Ningning Hou, Bing Chen, Chengxia Kan, Fang Han, Jingwen Zhang, Xiaodong Sun · 2022 · Frontiers in Pharmacology
10. Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells
    Debendra K. Mohapatra, D. Sai Reddy, Mekala Janaki Ramaiah, Sowjanya Ghosh, Vikram Pothula, Swetha Lunavath, Shine Thomas, S.N.C.V.L. Pushpa Valli, Manika Pal Bhadra, Jhillu Singh Yadav · 2014 · Bioorganic & Medicinal Chemistry Letters
11. B1, a novel naphthalimide-based DNA intercalator, induces cell cycle arrest and apoptosis in HeLa cells via p53 activation
    Xin Liang, Aibin Wu, Yufang F. Xu, Ke Xu, Jianwen Liu, Xuhong H. Qian · 2010 · Investigational New Drugs
12. Li-Fraumeni Syndrome: The Genetics and Treatment Considerations for the Sarcoma and Associated Neoplasms
    Brandi Upton, Quyen D. Chu, Benjamin D.�L. Li · 2008 · Surgical Oncology Clinics of North America
13. p53 in a Crosstalk Between DNA Repair and Cell Cycle Checkpoints
    Andrei L. Okorokov · 2003 · Cell Cycle
14. Leptin reduces apoptosis triggered by high temperature in human placental villous explants: The role of the p53 pathway
    Antonio Pérez‐Pérez, Ayelén Rayen Toro, Teresa Vilariño‐García, Pilar Guadix, Julieta Lorena Maymó, José L. Dueñas, Cecilia Laura Varone, Víctor Sánchez‐Margalet · 2016 · Placenta
15. DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide
    Ying Zhang, Guangpei Chen, Zhen Gu, Hai‐Jian Sun, Andrew C. Karaplis, David Goltzman, Dengshun Miao · 2018 · International Journal of Biological Sciences
16. An age‐related increase in resistance to DNA damage‐induced apoptotic cell death is associated with development of DNA repair mechanisms
    Alejandro A. Romero, Stephane R. Gross, Ke‐Yi Cheng, Noriko K. Goldsmith, Herbert M. Geller · 2003 · Journal of Neurochemistry
17. Why is there late replication?
    Erhard Wintersberger · 2000 · Chromosoma
18. The role of the p53 molecule in cancer therapies with radiation and/or hyperthermia.
    Takeo Ohnishi · 2005 · Journal of Cancer Research and Therapeutics
19. Abbreviated cell cycle progression induced by the serine/threonine protein phosphatase inhibitor okadaic acid at concentrations that promote neoplastic transformation
    Donald J. Messner · 2001 · Carcinogenesis
20. Negative Regulation of Mitotic Promoting Factor by the Checkpoint Kinase Chk1 in Simian Virus 40 Lytic Infection
    Eiji Okubo, John M. Lehman, Thomas D. Friedrich · 2002 · Journal of Virology
21. Roles of Claspin in regulation of DNA replication, replication stress responses and oncogenesis in human cells
    Hao-Wen Hsiao, Chi-Chun Yang, Hisao Masai · 2021 · Genome Instability & Disease
22. ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair
    Tilman Polonio-Vallon, Daniel Krüger, Thomas G. Hofmann · 2014 · Frontiers in Oncology
23. p53 Dimers Associate with a Head-to-Tail Response Element to Repress Cyclin B Transcription
    Robert Lipski, Daniel J. Lippincott, Brittany C. Durden, Anne R. Kaplan, Hilary E. Keiser, Jung‐Ho Park, Aime A. Levesque · 2012 · PLoS ONE
24. Chk1 protects against chromatin bridges by constitutively phosphorylating BLM serine 502 to inhibit BLM degradation
    Eleni Petsalaki, Maria Dandoulaki, Nick A. MORRICE, George Zachos · 2014 · Journal of Cell Science
25. ATM in focus: A damage sensor and cancer target
    Hilal S. Khalil, Hemanth Tummala, Nikolai Zhelev · 2012 · Biodiscovery
26. Total flavonoids ofEpimediumreduce ageing-related oxidative DNA damage in testis of rats via p53-dependent pathway
    Haixia Zhao, Song Li, Weifeng Huang, J. Liu, Ding Yuan, Yu Wang, Cong Zhang · 2017 · Andrologia
27. Analysis of the cytotoxic, genotoxic, mutagenic, and pro-oxidant effect of synephrine, a component of thermogenic supplements, in human hepatic cells in vitro
    Diego Luís Ribeiro, Ana Rita Thomazela Machado, Carla da Silva Machado, Patrick Wellington da Silva dos Santos, Alexandre F. Aissa, Gustavo Rafael Mazzaron Barcelos, Lusânia Maria Greggi Antunes · 2019 · Toxicology
28. Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process
    Alfredo Rodríguez, Leda Torres, Ulises Juárez, David Sosa, Eugenio M. Azpeitia, Benilde García‐de Teresa, Edith Cortés Barberena, Rocı́o Ortiz, Ana María Salazar, Patricia Ostrosky‐Wegman et al. · 2015 · Theoretical Biology and Medical Modelling
29. Absence of CHEK2*1100delC mutation in families with hereditary breast cancer in North America
    Maria D. Iniesta, Michael A. Gorin, Ling-Chen Chien, Samantha Marie Thomas, Kara J. Milliron, Julie A. Douglas, Sofia Diana Merajver · 2010 · Cancer Genetics and Cytogenetics
30. Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication
    Marco De Santis Puzzonia, Laetitia Gonzalez, Sonia Ascenzi, Enrico Cundari, Francesca Degrassi · 2015 · Cell Cycle
31. The p53 Tumor Suppressor Pathway and Cancer
    Gerard P. Zambetti · 2005 · Springer eBooks
32. Analysis of CHK2 in patients with myelodysplastic syndromes
    Dilek Aktaş, Matthew J Arno, Feyruz Virgilia Rassool, Ghulam Jeelani Mufti · 2002 · Leukemia Research
33. Regulation of p53-dependent transcription
    Arvi Jõers · 2004 · DSpace repository (University of Tartu)
34. A novel inhibitor, 2-cyano-3-(1-phenyl-3-(thiophen-2-yl)-pyrazol-4-yl)acrylamide linked to sulphamethoxazole, blocks anti-apoptotic proteins via molecular docking and strongly induced apoptosis of HCT116 cell line by different molecular tools
    Magda F. Mohamed, Heba K. Abdelhakim, Amna A. Saddiq, Ismail A. Abdelhamid · 2020 · Arabian Journal of Chemistry
35. Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics
    Fengjie Liu, Xu‐Yan Chen, Yang Jiao, Zhen Zhou Zhao, Qiao-Lei Wang, Ping Li, Yan Jiang, Hui‐Jun Li · 2022 · Phytomedicine
36. Medical Needs and Therapeutic Options for Melanoma Patients Resistant to Anti-PD-1-Directed Immune Checkpoint Inhibition
    Jessica C. Hassel, Lisa Zimmer, Thomas Sickmann, Thomas Eigentler, Friedegund Elke Meier, Peter Mohr, Tobias Pukrop, Alexander Roesch, Dirk Vordermark, Christina M. Wendl et al. · 2023 · Cancers
37. p22phox confers resistance to cisplatin, by blocking its entry into the nucleus
    Chih‐Chang Hung, Chen‐Yu Chien, Wei‐Fan Chiang, Chang‐Shen Lin, Tzyh‐Chyuan Hour, Hau‐Ren Chen, Ling‐Feng Wang, Jenq‐Yuh Ko, Chi‐Hua Chang, Jeff Yi‐Fu Chen · 2015 · Oncotarget
38. MicroRNAs and the DNA damage response: How is cell fate determined?
    Hartwig Visser, Adam D. Thomas · 2021 · DNA repair
39. Intracellular signalling and cancer: complex pathways lead to multiple targets
    Helen S. Bell, Kevin M. Ryan · 2004 · European Journal of Cancer
40. Checkpoint Kinase 1 Is Cleaved in a Caspase-Dependent Pathway during Genotoxic Stress-Induced Apoptosis
    Naoyuki Okita, Yuki Kudo, Sei‐ichi Tanuma · 2007 · Biological and Pharmaceutical Bulletin
41. Effect of ATM, CHEK2 and ERBB2 TAGSNPs and haplotypes on endometrial cancer risk
    Kristjana Einarsdóttir, Keith Humphreys, Carine Bonnard, Yuqing Li, Yi Li, Kee Seng Chia, Edison T. Liu, Per N Hall, Jianjun Liu, Sara Wedrén · 2006 · Human Molecular Genetics
42. Protein kinase inhibitor 2-aminopurine overrides multiple genotoxic stress-induced cellular pathways to promote cell survival
    Shirley H. Huang, Like Qu, Andrew R. Cuddihy, Rafik Ragheb, Yoichi Taya, Antonis E. Koromilas · 2003 · Oncogene
43. NBP is the p53 homolog p63
    Xuemei Zeng, Yuanzhao Zhu, Huiying Lu · 2001 · Carcinogenesis
44. Absence of Germline CHK2 Mutations in Familial Gastric Cancer
    Kenji Kimura, Kazuya Shinmura, Kimio Yoshimura, Kimihiro Shimizu, Hitoshi Katai, Yasuo Beppu, Hideshige Moriya, Jun Yokota · 2000 · Japanese Journal of Cancer Research
45. Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction
    Utsarga Adhikary, João A. Paulo, Marina Godes, Shrabasti Roychoudhury, Michelle S. Prew, Yael Ben‐Nun, Ellen W. Yu, Amit Budhraja, Joseph T. Opferman, Dipanjan Chowdhury et al. · 2023 · Cell Reports
46. Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells
    Amal A. El-Mabhouh, Mary Ayres, Elizabeth J. Shpall, Veerabhadran Baladandayuthapani, Michael J. Keating, William G. Wierda, Varsha V. Gandhi · 2014 · Blood
47. Giant cell formation: the way to cell death or cell survival?
    Rostyslav Horbay, Rostyslav S. Stoika · 2011 · Open Life Sciences
48. Simulating Molecular Mechanisms of the MDM2-Mediated Regulatory Interactions: A Conformational Selection Model of the MDM2 Lid Dynamics
    Gennady M. Verkhivker · 2012 · PLoS ONE
49. Cellular‐signaling pathways unveil the carcinogenic potential of chemicals
    Giel Hendriks, Bob van de Water, Willem G.E.J. Schoonen, Harry Vrieling · 2013 · Journal of Applied Toxicology
50. RUNX3 and p53: How Two Tumor Suppressors Cooperate Against Oncogenic Ras?
    Jung-Won Lee, André J. van Wijnen, Suk‐Chul Bae · 2017 · Advances in experimental medicine and biology
51. Quantitative Profiling of DNA Damage and Apoptotic Pathways in UV Damaged Cells Using PTMScan Direct
    Matthew P. Stokes, Jeffrey C. Silva, Xiaoying Jia, Kimberly Lee, Roberto D. Polakiewicz, Michael J. Comb · 2012 · International Journal of Molecular Sciences
52. Lysines in the tetramerization domain of p53 selectively modulate G1 arrest
    Rachel Beckerman, Kathryn E. Yoh, Melissa Mattia-Sansobrino, Andrew Zupnick, Oleg Laptenko, Orit Karni-Schmidt, Jinwoo Ahn, In‐Ja L. Byeon, Susan M. Keezer, Carol L. Prives · 2016 · Cell Cycle
53. p53‐mediated downregulation of Chk1 abrogates the DNA damage‐induced G2M checkpoint in K562 cells, resulting in increased apoptosis
    Michele Cummings, Timo Siitonen, Karen Higginbottom, Adrian C. Newland, Paul D. Allen · 2002 · British Journal of Haematology
54. Cloning and Characterization of Liver-specific Isoform of Chk1 Gene from Rat
    Yih‐Jyh Shann, Ming‐Ta Hsu · 2001 · Journal of Biological Chemistry
55. Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage
    Chen Chen, Shigeomi Shimizu, Yoshihide Tsujimoto, Noboru Motoyama · 2005 · Biochemical and Biophysical Research Communications
56. Tumor Suppression by p53 in the Absence of Atm
    Shawn Lawrence Bailey, Kay E. Gurley, Kyung Hoon-Kim, Karen S. Kelly‐Spratt, Christopher J. Kemp · 2008 · Molecular Cancer Research
57. DNA Damage Induces p53-dependent Down-regulation of hCHK1
    Giovanna L.M. Damia, Yolanda Sánchez, Eugenio Erba, Massimo Broggini · 2001 · Journal of Biological Chemistry
58. The key vulnerabilities and therapeutic opportunities in the USP7-p53/MDM2 axis in cancer
    Gouranga Saha, Mrinal K. Ghosh · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
59. Accumulation of Fat Not Responsible for Femoral Head Necrosis, Revealed by Single-Cell RNA Sequencing: A Preliminary Study
    Yingjie Wang, Dandan Li, Haijia Chen, Zhuolin Li, Bin Feng, Xisheng Weng · 2023 · Biomolecules
60. Analysis of ataxia-telangiectasia mutated (ATM)- and Nijmegen breakage syndrome (NBS)-regulated gene expression patterns
    Eun Ryoung Jang, Joo Hyen Lee, Dae‐Sik Lim, Jong‐Soo Lee · 2004 · Journal of Cancer Research and Clinical Oncology
61. Chek2 DNA Damage Response Pathway and Inherited Breast Cancer Risk
    Nadine Tung, Daniel P. Silver · 2011 · Journal of Clinical Oncology
62. Germline mutations in a DNA repair pathway are associated with familial colorectal cancer
    Pingping Xu, Danfeng Sun, Yaqi Gao, Yi Jiang, Ming Zhong, Gang Zhao, Jinxian Chen, Zheng Wang, Qiang Liu, Jie Hong et al. · 2021 · JCI Insight
63. p53 protein accumulation in addition to the transactivation activity is required for p53-dependent cell cycle arrest after treatment of cells with camptothecin
    Viljar Jaks, Arvi Jõers, Arnold Kristjuhan, Toivo Maimets · 2001 · Oncogene
64. ATM: Sounding the Double-strand Break Alarm
    Yosef Shiloh · 2000 · Cold Spring Harbor Symposia on Quantitative Biology
65. Recombinant, refolded tetrameric p53 and gonadotropin-releasing hormone-p53 slow proliferation and induce apoptosis in p53-deficient cancer cells
    Michelle A. LaFevre-Bernt, Shili Wu, Xinli Lin · 2008 · Molecular Cancer Therapeutics
66. Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells
    Iraia García‐Santisteban, Alba Llopis, Lenno Krenning, Jon Vallejo-Rodríguez, Bram van den Broek, Ana M. Zubiaga, René H. Medema · 2021 · BMC Biology
67. Polyploidization and Cancer
    Randy Y.C. Poon · 2010 · Advances in experimental medicine and biology
68. Mutational analysis of Chk1, Chk2, Apaf1 and Rb1 in human malignant melanoma cell lines
    Thilo Papp, Annett Niemetz, Nils Dosdahl, Krishan Kumar, Dietmar Schiffmann · 2007 · Oncology Reports
69. Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells
    Matthew T. Balmer, Ryan D Katz, Si Liao, James S. Goodwine, Susannah Gal · 2014 · Cancer Biology & Therapy
70. Gene expression patterns in heterozygous Plk4 murine embryonic fibroblasts
    Alan Morettin, Alejandra Ward, Jordan Nantais, John W. Hudson · 2009 · BMC Genomics
71. The Janus Face of p53-Targeting Ubiquitin Ligases
    Qian Hao, Yajie Chen, Xiang Yu Zhou · 2020 · Cells
72. MicroRNA-221/222 Inhibits the Radiation-Induced Invasiveness and Promotes the Radiosensitivity of Malignant Meningioma Cells
    Qing Hua Zhang, Lairong Song, Xulei Huo, Liang Wang, Guo-Bin Zhang, Shuyu Hao, Hai-wei Jia, Chui-Lin Kong, Wang Jia, Zhen Wu et al. · 2020 · Frontiers in Oncology
73. DNA damage checkpoints in nasopharyngeal carcinoma
    Randy Y.C. Poon · 2014 · Oral Oncology
74. Cell-cycle Alterations in Post-mitotic Cells and Cell Death by Mitotic Catastrophe
    Duccio Lombardi, Laura Lasagni · 2016 · InTech eBooks
75. Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner
    J. Jacob Wamsley, C. Gary, Asel Biktasova, M Hajek, Gary Bellinger, Renu K. Virk, Natalia Issaeva, Wendell Gray Yarbrough · 2017 · Oncogenesis
76. Breaking the DNA Damage Response via Serine/Threonine Kinase Inhibitors to Improve Cancer Treatment
    Wioletta Rozpędek‐Kamińska, Dariusz Pytel, Alicja Nowak-Zduńczyk, Dawid Lewko, Radosław Wojtczak, John Alan Diehl, Ireneusz Majsterek · 2018 · Current Medicinal Chemistry
77. Jun N-terminal kinase activation and upregulation of p53 and p21WAF1/CIP1 in selenite-induced apoptosis of regenerating liver
    Rieko Nango, Chieko Terada, Ikuyo Tsukamoto · 2003 · European Journal of Pharmacology
78. Disrupting the p53-mdm2 interaction as a potential therapeutic modality
    Ute Martha Moll, Alex Zaika · 2000 · Drug Resistance Updates
79. Germline CHEK2*1100delC mutations in breast cancer patients with multiple primary cancers
    Jia Huang, S M Domchek, M S Brose, Timothy Richard Rebbeck, Katherine L. Nathanson, B L Weber · 2004 · Journal of Medical Genetics
80. N-Methyl-N′-nitro-N-nitrosoguanidine Activates Cell-Cycle Arrest through Distinct Mechanisms Activated in a Dose-Dependent Manner
    Dillon I. Beardsley, Wan-Ju Kim, Kevin D. Brown · 2005 · Molecular Pharmacology
81. The FHA Domain, a Phosphoamino Acid Binding Domain Involved in the DNA Damage Response Pathway
    Mingxia Huang, Stephen Joseph Elledge · 2000 · Cold Spring Harbor Symposia on Quantitative Biology
82. Maintaining Genome Integrity: Protein Kinases and Phosphatases Orchestrate the Balancing Act of DNA Double-Strand Breaks Repair in Cancer
    Sisi Qin, Ichiwa Kitty, Yalan Hao, Fei Zhao, Wootae Kim · 2023 · International Journal of Molecular Sciences
83. Variant allele of CHEK2 is associated with a decreased risk of esophageal cancer lymph node metastasis in a Chinese population
    Haiyong Gu, Wanshan Qiu, Ying Wan, Guowen Ding, Weifeng Tang, Chao Liu, Yijun Shi, Yijang Chen, Suocheng Chen · 2011 · Molecular Biology Reports
84. A spatiotemporal characterization of the effect of p53 phosphorylation on its interaction with MDM2
    Karim M. ElSawy, Adelene Y. L. Sim, David Philip Lane, Chandra Shekhar Verma, Leo S. D. Caves · 2015 · Cell Cycle
85. Gene and protein analysis reveals that p53 pathway is functionally inactivated in cytogenetically normal Acute Myeloid Leukemia and Acute Promyelocytic Leukemia
    Julia Abramowitz, Tzahi Neuman, Riki Perlman, Dina Ben‐Yehuda · 2017 · BMC Medical Genomics
86. DNA Damage Response Pathways and Cancer
    James M. Ford, Michael B. Kastan · 2014 · Elsevier eBooks
87. PKR-Mediated Phosphorylation of eIF2a and CHK1 Is Associated with Doxorubicin-Mediated Apoptosis in HCC1143 Triple-Negative Breast Cancer Cells
    Sol Lee, Ha-Yeon Jee, Yoon-Gyeong Lee, Jong-Il Shin, Yong-Joon Jeon, Ji-Beom Kim, Hye-eun Seo, Ji‐Yeon Lee, Kyung‐Ho Lee · 2022 · International Journal of Molecular Sciences
88. BH3 mimetics targeting BCL-XL have efficacy in solid tumors with RB1 loss and replication stress
    Andreas S. Varkaris, Keshan Wang, Mannan Nouri, Nina V. Kozlova, Daniel R. Schmidt, Anastasia-Maria Stavridi, Seiji Arai, Nicholas Ambrosio, Larysa Poluben, Juan M. Jiménez‐Vacas et al. · 2025 · Nature Communications
89. The role of the DNA damage response kinase ataxia telangiectasia mutated in neuroprotection.
    Konstantina Marinoglou · 2012 · Europe PMC (PubMed Central)
90. Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21
    Marijn T. M. van Jaarsveld, Difan Deng, Erik A.C. Wiemer, Zhike Zi · 2019 · iScience
91. Real-time surface plasmon resonance monitoring of site-specific phosphorylation of p53 protein and its interaction with MDM2 protein
    Ling Wu, Yuhan He, Yuqing Hu, Hanwen Lu, Zhong Yi Cao, Xinyao Yi, Jianxiu Wang · 2019 · The Analyst
92. Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants
    Barbara Mlody, Wasco Wruck, Soraia Martins, Karl Sperling, James Adjaye · 2017 · Scientific Reports
93. Mechanism-Based Screen Establishes Signalling Framework for DNA Damage-Associated G1 Checkpoint Response
    Elizabeth Richardson, Simon R. Stockwell, He Li, Wynne Aherne, Maria Emanuela Cuomo, Sibylle Mittnacht · 2012 · PLoS ONE
94. Analysis of familial male breast cancer for germline mutations in CHEK2
    Nayanta Sodha, Charlotte Wilson, Sarah L. Bullock, Hazel Phillimore, Richard S. Houlston, Rosalind A. Eeles · 2004 · Cancer Letters
95. Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl) ethenyl]-quinazoline induces G2/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells
    JONG-YUN KIM, Hye‐Eun Choi, Hwi‐Ho Lee, Ji‐Sun Shin, DONG-HYUN SHIN, Jung‐Hye Choi, Yong Sup Lee, Kyung‐Tae Lee · 2015 · Oncology Reports
96. Analysis of p53 Gene Alterations in Cancer: A Critical View
    Thierry Soussi · 2005 · Springer eBooks
97. Single‐nucleotide polymorphisms in the p53 pathway genes modify cancer risk in BRCA1 and BRCA2 carriers of Jewish‐Ashkenazi descent
    Ronit I. Yarden, Eitan Friedman, Sally Metsuyanim, Tzvia Olender, Edna Ben‐Asher, Moshe Zvi Papa · 2010 · Molecular Carcinogenesis
98. Cheliensisin A Inhibits EGF-Induced Cell Transformation with Stabilization of p53 Protein Via a Hydrogen Peroxide/Chk1-Dependent Axis
    Jingjie Zhang, Guangxun Gao, Liang Chen, Xu Deng, Jingxia Li, Yonghui Yu, Dongyun Zhang, Fei Li, Min Zhang, Qin‐Shi Zhao et al. · 2013 · Cancer Prevention Research
99. CHK1 regulates NF-κB signaling upon DNA damage in p53- deficient cells and associated tumor-derived microvesicles
    Brittany L. Carroll, Michael J. Pulkoski‐Gross, Yusuf Awni Hannun, Lina Marie Obeid · 2016 · Oncotarget
100. Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation
     Fanghua Li, Emil Mladenov, Rositsa Dueva, Martin Stuschke, Beate Timmermann, George E. Iliakis · 2021 · Cells