The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Cadherins in development: cell adhesion, sorting, and tissue morphogenesis
Open accessAbstract
Tissue morphogenesis during development is dependent on activities of the cadherin family of cell–cell adhesion proteins that includes classical cadherins, protocadherins, and atypical cadherins (Fat, Dachsous, and Flamingo). The extracellular domain of cadherins contains characteristic repeats that regulate homophilic and heterophilic interactions during adhesion and cell sorting. Although cadherins may have originated to facilitate mechanical cell–cell adhesion, they have evolved to function in many other aspects of morphogenesis. These additional roles rely on cadherin interactions with a wide range of binding partners that modify their expression and adhesion activity by local regulation of the actin cytoskeleton and diverse signaling pathways. Here we examine how different members of the cadherin family act in different developmental contexts, and discuss the mechanisms involved.
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Cites
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“This is further supported by experiments in fibroblasts expressing different cadherins that show sorting out of mixed cell populations is mediated by surface expression levels of cadherins (Duguay et al. 2003; Foty and Steinberg 2005).”
InfluentialWNT signalling molecules act in axis formation in the diploblastic metazoan Hydra
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Self-citationRegulation of motor neuron pool sorting by differential expression of type II cadherins
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Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization
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Cited by
Nieto, M. A., Huang, R. Y.-J., Jackson, R. A., & Thiery, J. P. (2016) · Cell · doi:10.1016/j.cell.2016.06.028 · Cited by 4,492
Zhao, B., Wei, X., Li, W., Udan, R. S., Yang, Q., Kim, J., Xie, J., Ikenoue, T., Yu, J., Li, L., et al. (2007) · Genes & Development · doi:10.1101/gad.1602907 · Cited by 3,092
Intestinal barrier function: molecular regulation and disease pathogenesis
Groschwitz, K. R., & Hogan, S. P. (2009) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2009.05.038 · Cited by 1,775
The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans
King, N., Westbrook, M. J., Young, S. L., Kuo, A., Abedin, M., Chapman, J., Fairclough, S., Hellsten, U., Isogai, Y., Letunic, I., et al. (2008) · Nature · doi:10.1038/nature06617 · Cited by 1,139
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Metadata
- Authors
- Halbleib, J. M., & Nelson, W. J.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2006-12-01
- Volume
- 20
- Issue
- 23
- Pages
- 3199-3214
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2117933964
- Cited by
- 1,064
- References
- 7
- Type
- posted content
- Language
- en
- Open access
- diamond
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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