The DOI matches its Crossref record; 169 of the 169 references it cites were found in a registry or an index.
Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm
Open accessAbstract
Intermediate filaments (IFs) are cytoskeletal polymers whose protein constituents are encoded by a large family of differentially expressed genes. Owing in part to their properties and intracellular organization, IFs provide crucial structural support in the cytoplasm and nucleus, the perturbation of which causes cell and tissue fragility and accounts for a large number of genetic diseases in humans. A number of additional roles, nonmechanical in nature, have been recently uncovered for IF proteins. These include the regulation of key signaling pathways that control cell survival, cell growth, and vectorial processes including protein targeting in polarized cellular settings. As this discovery process continues to unfold, a rationale for the large size of this family and the context-dependent regulation of its members is finally emerging.
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Datta, A., Deng, S., Gopal, V., Yap, K. C.-H., Halim, C. E., Lye, M. L., Ong, M. S., Tan, T. Z., Sethi, G., Hooi, S. C., et al. (2021) · Cancers · doi:10.3390/cancers13081882 · Cited by 184
Vardjan, N., Gabrijel, M., Potokar, M., Švajger, U., Kreft, M., Jeras, M., de Pablo, Y., Faiz, M., Pekny, M., & Zorec, R. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-144 · Cited by 117
Vimentin Regulates Scribble Activity by Protecting It from Proteasomal Degradation
Phua, D. C. Y., Humbert, P. O., & Hunziker, W. (2009) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-02-0199 · Cited by 68
Nuclear Mechanotransduction in Skeletal Muscle
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Metadata
- Authors
- Kim, S., & Coulombe, P. A.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2007-07-01
- Volume
- 21
- Issue
- 13
- Pages
- 1581-1597
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2138424169
- Cited by
- 316
- References
- 169
- Type
- posted content
- Language
- en
- Open access
- diamond
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