Unraveling the crucial roles of Meis1 in leukemogenesis and normal hematopoiesis

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

Yeoh, A. E. J., Ross, M. E., Shurtleff, S. A., Williams, W. K., Patel, D. H., Mahfouz, R. A., Behm, F. G., Raimondi, S. C., Relling, M. V., Patel, A. R., et al. (2002) · Cancer Cell · doi:10.1016/s1535-6108(02)00032-6 · Cited by 1,914

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

Armstrong, S. A., Staunton, J. E., Silverman, L. B., Pieters, R., den Boer, M. L., Minden, M. D., Sallan, S. E., Lander, E. S., Golub, T. R., & Korsmeyer, S. J. (2001) · Nature Genetics · doi:10.1038/ng765 · Cited by 1,721

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells.

Lessard, J., & Sauvageau, G. (2003) · Nature · doi:10.1038/nature01572 · Cited by 1,452

Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity

Hope, K. J., Jin, L., & Dick, J. E. (2004) · Nature Immunology · doi:10.1038/ni1080 · Cited by 986

Altered Hox expression and segmental identity in Mll-mutant mice

Yu, B., Hess, J. L., Horning, S. E., Brown, G. A. J., & Korsmeyer, S. J. (1995) · Nature · doi:10.1038/378505a0 · Cited by 872

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

Kroon, E., Krosl, J., Thorsteinsdottir, U., Baban, S., Buchberg, A. M., & Sauvageau, G. (1998) · The EMBO Journal · doi:10.1093/emboj/17.13.3714 · Cited by 640

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia

Somervaille, T. C. P., & Cleary, M. L. (2006) · Cancer Cell · doi:10.1016/j.ccr.2006.08.020 · Cited by 582

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

Iwama, A., Oguro, H., Negishi, M., Kato, Y., Morita, Y., Tsukui, H., Ema, H., Kamijo, T., Katoh-Fukui, Y., Koseki, H., et al. (2004) · Immunity · doi:10.1016/j.immuni.2004.11.004 · Cited by 515

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

Miyamoto, T., Weissman, I. L., & Akashi, K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.13.7521 · Cited by 465

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

Taussig, D. C. (2005) · Blood · doi:10.1182/blood-2005-03-1072 · Cited by 379

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

Simsek, T., Kocabas, F., Zheng, J., DeBerardinis, R. J., Mahmoud, A. I., Olson, E. N., Schneider, J. W., Zhang, C. C., & Sadek, H. A. (2010) · Cell Stem Cell · doi:10.1016/j.stem.2010.07.011 · Cited by 1,101

Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery

Burslem, G. M., & Crews, C. M. (2020) · Cell · doi:10.1016/j.cell.2019.11.031 · Cited by 1,079

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

Novershtern, N., Subramanian, A., Lawton, L. N., Mak, R. H., Haining, W. N., McConkey, M. E., Habib, N., Yosef, N., Chang, C. Y., Shay, T., et al. (2011) · Cell · doi:10.1016/j.cell.2011.01.004 · Cited by 942

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

Mahmoud, A. I., Kocabaş, F., Muralidhar, S. A., Kimura, W., Koura, A. S., Thet, S., Porrello, E. R., & Sadek, H. A. (2013) · Nature · doi:10.1038/nature12054 · Cited by 565

EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cellsPreprint

Riggi, N., Suvà, M.-L., Vito, C. D., Provero, P., Stehle, J., Baumer, K., Cironi, L., Janiszewska, M., Petricevic, T., Suvà, D., et al. (2010) · Genes & Development · doi:10.1101/gad.1899710 · Cited by 281

Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells

Kocabaş, F., Zheng, J., Thet, S., Copeland, N. G., Jenkins, N. A., DeBerardinis, R. J., Zhang, C. C., & Sadek, H. A. (2012) · Blood · doi:10.1182/blood-2012-05-432260 · Cited by 235

Hypoxia and Metabolic Properties of Hematopoietic Stem Cells

Zhang, C. C., & Sadek, H. A. (2013) · Antioxidants and Redox Signaling · doi:10.1089/ars.2012.5019 · Cited by 160

Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)

Fiskus, W. C., Boettcher, S., Daver, N. G., Mill, C. P., Sasaki, K., Birdwell, C. E., Davis, J. A., Takahashi, K., Kadia, T. M., Dinardo, C. D., et al. (2022) · Blood Cancer Journal · doi:10.1038/s41408-021-00603-3 · Cited by 141

Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance

Buscarlet, M., Krasteva, V., Ho, L., Simon, C., Hébert, J., Wilhelm, B. T., Crabtree, G. R., Sauvageau, G., Thibault, P., & Lessard, J. A. (2014) · Blood · doi:10.1182/blood-2013-02-483495 · Cited by 125

Iron, dopamine, genetics, and hormones in the pathophysiology of restless legs syndrome

Khan, F. H., Ahlberg, C. D., Chow, C. A., Shah, D. R., & Koo, B. B. (2017) · Journal of Neurology · doi:10.1007/s00415-017-8431-1 · Cited by 114

Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia

Mingay, M., Chaturvedi, A., Bilenky, M., Cao, Q., Jackson, L., Hui, T., Moksa, M., Heravi-Moussavi, A., Humphries, R. K., Heuser, M., et al. (2018) · Leukemia · doi:10.1038/leu.2017.171 · Cited by 94

Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1

Fiskus, W. C., Daver, N. G., Boettcher, S., Mill, C. P., Sasaki, K., Birdwell, C. E., Davis, J. A., Das, K., Takahashi, K., Kadia, T. M., et al. (2022) · Leukemia · doi:10.1038/s41375-022-01707-w · Cited by 83

Hypoxic metabolism in human hematopoietic stem cells

Kocabaş, F., Xie, L., Xie, J., Yu, Z., DeBerardinis, R. J., Kimura, W., Thet, S., Elshamy, A. F., Abouellail, H. A., Muralidhar, S. A., et al. (2015) · Cell & Bioscience · doi:10.1186/s13578-015-0020-3 · Cited by 79

Association studies of variants in MEIS1, BTBD9, and MAP2K5/SKOR1 with restless legs syndrome in a US population

Yang, Q., Li, L., Chen, Q., Foldvary‐Schaefer, N., Ondo, W. G., & Wang, Q. K. (2011) · Sleep Medicine · doi:10.1016/j.sleep.2011.06.006 · Cited by 78

MEIS transcription factors in development and disease

Schulte, D., & Geerts, D. (2019) · Development · doi:10.1242/dev.174706 · Cited by 73

Mechanisms of iron metabolism in Caenorhabditis elegans

Anderson, C. P., & Leibold, E. A. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00113 · Cited by 77

PPM1K Regulates Hematopoiesis and Leukemogenesis through CDC20-Mediated Ubiquitination of MEIS1 and p21

Liu, X., Zhang, F., Zhang, Y., Xie, L., Chen, C., Zhou, M., Yu, Z., Liu, Y., Zhao, Y., Hao, X., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.03.140 · Cited by 76

Identification of Pbx1 , a Potential Oncogene, as a Notch3 Target Gene in Ovarian Cancer

Park, J. T., Shih, I., & Wang, T. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-0517 · Cited by 74

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification

Gilmour, J., Assi, S. A., Jägle, U., Kulu, D., van de Werken, H. J. G., Clarke, D., Westhead, D. R., Philipsen, S., & Bonifer, C. (2014) · Development · doi:10.1242/dev.106054 · Cited by 75

Dpp dependent Hematopoietic stem cells give rise to Hh dependent blood progenitors in larval lymph gland of Drosophila

Dey, N. S., Ramesh, P., Chugh, M., Mandal, S., & Mandal, L. (2016) · eLife · doi:10.7554/elife.18295 · Cited by 66

GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis

Dietrich, P. A., Yang, C., Leung, H. H. L., Lynch, J. R., Gonzales‐Aloy, E., Liu, B., Haber, M., Norris, M. D., Wang, J., & Wang, J. Y. (2014) · Blood · doi:10.1182/blood-2013-10-532523 · Cited by 63

Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1

Fiskus, W. C., Mill, C. P., Birdwell, C. E., Davis, J. A., Das, K., Boettcher, S., Kadia, T. M., Dinardo, C. D., Takahashi, K., Loghavi, S., et al. (2023) · Blood Cancer Journal · doi:10.1038/s41408-023-00826-6 · Cited by 57

LncRNA SNORD3A specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression

Luo, L., Zhang, J., Tang, H., Zhai, D., Huang, D., Li, L., Wang, X., Liu, T., Zhang, Q., Zhang, Z., et al. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2557-2 · Cited by 55

Acute Myeloid Leukemia and the Wnt Pathway

Eaves, C. J., & Humphries, R. K. (2010) · New England Journal of Medicine · doi:10.1056/nejmcibr1003522 · Cited by 52

HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancer

Johng, D., Torga, G., Ewing, C. M., Jin, K., Norris, J. D., McDonnell, D. P., & Isaacs, W. B. (2018) · The Prostate · doi:10.1002/pros.23747 · Cited by 49

MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML

Naidu, V. M., Klappacher, J., Oswald, F., Mulaw, M. A., Mandoli, A., Thiel, V. N., Bamezai, S., Feder, K., Martens, J. H. A., Rawat, V. P. S., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.094 · Cited by 47

MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycans

VanOpstall, C., Perike, S., Brechka, H., Gillard, M., Lamperis, S. M., Zhu, B., Brown, R. M., Bhanvadia, R. R., & Griend, D. J. V. (2020) · eLife · doi:10.7554/elife.53600 · Cited by 47

Beyond Hox: the role of ParaHox genes in normal and malignant hematopoiesis

Rawat, V. P. S., Humphries, R. K., & Buske, C. (2012) · Blood · doi:10.1182/blood-2012-02-385898 · Cited by 46

The role of meis1 in primitive and definitive hematopoiesis during zebrafish development

Cvejic, A., Serbanovic‐Canic, J., Stemple, D. L., & Ouwehand, W. H. (2010) · Haematologica · doi:10.3324/haematol.2010.027698 · Cited by 44

Trithorax, Hox, and TALE-class homeodomain proteins ensure cell survival through repression of the BH3-only gene egl-1.

Potts, M. B., Wang, D., & Cameron, S. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.02.022 · Cited by 50

Development of Small Molecule MEIS Inhibitors that modulate HSC activity

Turan, R. D., Albayrak, E., Uslu, M., Si̇yah, P., Alyazici, L. Y., Kalkan, B. M., Aslan, G. S., Yücel, D., Aksöz, M., Tüysüz, E. C., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-64888-3 · Cited by 41

Upregulation of CD11b and CD86 through LSD1 inhibition promotes myeloid differentiation and suppresses cell proliferation in human monocytic leukemia cells

Fang, J., Ying, H., Mao, T., Fang, Y., Lu, Y., Wang, H., Zang, I., Wang, Z., Lin, Y., Zhao, M., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.18564 · Cited by 39

MEIS1, PREP1, and PBX4 Are Differentially Expressed in Acute Lymphoblastic Leukemia: Association of MEIS1 Expression with Higher Proliferation and Chemotherapy Resistance

Rosales-Aviña, J. A., Torres-Flores, J., Aguilar‐Lemarroy, A., Gurrola‐Díaz, C. M., Hernández‐Flores, G., Ortiz‐Lazareno, P. C., Lerma-Díaz, J. M., Célis, R. D., Gonzalez-Ramella, O. R., Barrera‐Chairez, E., et al. (2011) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/1756-9966-30-112 · Cited by 37

Transcriptome Profiling Reveals Disruption of Innate Immunity in Chronic Heavy Ethanol Consuming Female Rhesus Macaques

Sureshchandra, S., Rais, M., Stull, C., Grant, K. A., & Messaoudi, I. (2016) · PLoS ONE · doi:10.1371/journal.pone.0159295 · Cited by 36

Higher expression levels of the HOXA9 gene, closely associated with MLL-PTD and EZH2 mutations, predict inferior outcome in acute myeloid leukemia

Gao, L., Sun, J., Liu, F., Zhang, H., & Ma, Y.-G. (2016) · OncoTargets and Therapy · doi:10.2147/ott.s95279 · Cited by 35

RE-IIBP Methylates H3K79 and Induces MEIS1-mediated Apoptosis via H2BK120 Ubiquitination by RNF20

Park, J. W., Kim, K., Kim, J., Chae, Y., Jeong, O.-S., & Seo, S. (2015) · Scientific Reports · doi:10.1038/srep12485 · Cited by 34

Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1

Liu, J., Wang, Y., Birnbaum, M. J., & Stoffers, D. A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1007001107 · Cited by 36

HOXA9 and MEIS1 gene overexpression in the diagnosis of childhood acute leukemias: Significant correlation with relapse and overall survival

Adamaki, M., Lambrou, G. Ι., Athanasiadou, A., Vlahopoulos, S., Papavassiliou, A. G., & Moschovi, M. A. (2015) · Leukemia Research · doi:10.1016/j.leukres.2015.04.012 · Cited by 33

Correlation Between Meis1 and Msi1 in Esophageal Squamous Cell Carcinoma

Moghbeli, M., Rad, A., Farshchian, M., Taghehchian, N., Gholamin, M., & Abbaszadegan, M. R. (2016) · Journal of Gastrointestinal Cancer · doi:10.1007/s12029-016-9824-6 · Cited by 29

Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation

Roode, S. C., Rotroff, D. M., Avery, A. C., Suter, S. E., Bienzle, D., Schiffman, J. D., Motsinger‐Reif, A. A., & Breen, M. (2015) · Chromosome Research · doi:10.1007/s10577-015-9475-7 · Cited by 29

Identification of E74-like factor 1 (ELF1) as a transcriptional regulator of the Hox cofactor MEIS1

Xiang, P., Lo, C., Argiropoulos, B., Lai, C. B., ROUHI, A. M., Imren, S., Jiang, X., Mager, D. L., & Humphries, R. K. (2010) · Experimental Hematology · doi:10.1016/j.exphem.2010.06.006 · Cited by 27

Cell lineage and cell death: Caenorhabditis elegans and cancer research

Potts, M. B., & Cameron, S. (2010) · Nature reviews. Cancer · doi:10.1038/nrc2984 · Cited by 30

Zebrafish hoxd4a Acts Upstream of meis1.1 to Direct Vasculogenesis, Angiogenesis and Hematopoiesis

Amali, A. A., Sie, L., Winkler, C., & Featherstone, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058857 · Cited by 28

Meis1 regulates proliferation of non-small-cell lung cancer cells.

Li, W., Huang, K., Guo, H., & Cui, G. (2014) · PubMed Central · doi:10.3978/j.issn.2072-1439.2014.06.03 · Cited by 28

The Molecular Genetics of Restless Legs Syndrome

Rye, D. B. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2015.05.015 · Cited by 27

The Corepressor Rcor1 Is Essential for Normal Myeloerythroid Lineage Differentiation

Yao, H., Goldman, D. C., Fan, G., Mandel, G., & Fleming, W. (2015) · Stem Cells · doi:10.1002/stem.2086 · Cited by 24

The molecular basis of restless legs syndrome

Freeman, A. A. H., & Rye, D. B. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.07.001 · Cited by 25

Integrated analysis of DNA methylation and microRNA regulation of the lung adenocarcinoma transcriptome

Du, J., & ZHANG, L. (2015) · Oncology Reports · doi:10.3892/or.2015.4023 · Cited by 25

Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia

Tanaka, A., Nakano, T. A., Nomura, M., Yamazaki, H., Bewersdorf, J. P., Mulet‐Lazaro, R., Hogg, S. J., Liu, B., Penson, A., Yokoyama, A., et al. (2022) · Blood · doi:10.1182/blood.2021015325 · Cited by 25

Homeobox gene Meis1 modulates cardiovascular regeneration

Paul, S., Zhang, X., & He, J. (2019) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2019.10.003 · Cited by 25

Condensate-Promoting ENL Mutation Drives Tumorigenesis In Vivo Through Dynamic Regulation of Histone Modifications and Gene Expression

Liu, Y., Li, Q., Song, L., Gong, C., Tang, S., Budinich, K. A., Vanderbeck, A., Mathias, K. M., Wertheim, G. B. W., Nguyen, S. C., et al. (2024) · Cancer Discovery · doi:10.1158/2159-8290.cd-23-0876 · Cited by 23

Transcriptional Activation by MEIS1A in Response to Protein Kinase A Signaling Requires the Transducers of Regulated CREB Family of CREB Co-activators

Goh, S.-L., Looi, Y., Shen, H., Fang, J. Q., Bodner, C., Houle, M., Ng, A. C., Screaton, R. A., & Featherstone, M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.005090 · Cited by 22

The cancer paradigms of mammalian regeneration: can mammals regenerate as amphibians?

Sarig, R., & Tzahor, E. (2016) · Carcinogenesis · doi:10.1093/carcin/bgw103 · Cited by 22

The homeodomain transcription factor MEIS1 triggers chemokine expression and is involved in CD8+ T‐lymphocyte infiltration in early stage ovarian cancer

Karapetsas, A., Tokamani, M., Evangelou, C., & Sandaltzopoulos, R. (2018) · Molecular Carcinogenesis · doi:10.1002/mc.22840 · Cited by 21

Two new targeted alleles for the comprehensive analysis of M eis1 functions in the mouse

González‐Lázaro, M., Roselló‐Díez, A., Delgado, I., Carramolino, L., Sanguino, M. A., Giovinazzo, G., & Torres, M. (2014) · genesis · doi:10.1002/dvg.22833 · Cited by 21

Meis1 is specifically upregulated in kidney myofibroblasts during aging and injury but is not required for kidney homeostasis or fibrotic response

Chang-Panesso, M., Kadyrov, F. F., Machado, F. G., Kumar, A. R., & Humphreys, B. D. (2018) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00030.2018 · Cited by 22

Promoter methylation and expression levels of selected hematopoietic genes in pediatric B-cell acute lymphoblastic leukemia

Musialik‐Świetlińska, E., Bujko, M., Kober, P., Wypych, A., Gawle‐Krawczyk, K., Matysiak, M. J., & SIEDLECKI, J. A. (2015) · Blood Research · doi:10.5045/br.2015.50.1.26 · Cited by 20

Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression

Coulombe, P., Cole, G., Fentiman, A., Parker, J., Yung, E., Bilenky, M., Degefie, L. T., Lac, P., Ling, M. Y. M., Tam, D., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-40283-0 · Cited by 20

Promoter DNA methylation and expression levels of HOXA4, HOXA5 and MEIS1 in acute myeloid leukemia

Musialik‐Świetlińska, E., Bujko, M., Kober, P., Grygorowicz, M. A., Libura, M. A., Przestrzelska, M., Juszczyński, P., Borg, K., Florek, I., Jakóbczyk, M., et al. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3196 · Cited by 19

Role of MAML1 and MEIS1 in Esophageal Squamous Cell Carcinoma Depth of Invasion

Abbaszadegan, M. R., & Moghbeli, M. (2017) · Pathology & Oncology Research · doi:10.1007/s12253-017-0243-1 · Cited by 19

De Novo Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells for Cellular Therapy

Ding, J., Li, Y., & Larochelle, A. (2023) · Cells · doi:10.3390/cells12020321 · Cited by 17

Discrete regulatory modules instruct hematopoietic lineage commitment and differentiation

Georgolopoulos, G., Psatha, N., Iwata, M., Nishida, A., Som, T., Yiangou, M., Stamatoyannopoulos, J. A., & Vierstra, J. D. (2021) · Nature Communications · doi:10.1038/s41467-021-27159-x · Cited by 16

Transcriptional Regulation of Stem Cell and Cancer Stem Cell Metabolism

Alptekin, A., Ye, B., & Ding, H. (2017) · Current Stem Cell Reports · doi:10.1007/s40778-017-0071-y · Cited by 16

Elucidating the importance and regulation of key enhancers for human MEIS1 expression

Xiang, P., Yang, X., Escano, L., Dhillon, I., Schneider, E. M., Clemans-Gibbon, J., Wei, W., Wong, J., Wang, S. X., Tam, D., et al. (2022) · Leukemia · doi:10.1038/s41375-022-01602-4 · Cited by 17

Comparative analysis of the Mexico City Prospective Study and the UK Biobank identifies ancestry-specific effects on clonal hematopoiesis

Wen, S., Kuri-Morales, P. A., Hu, F., Nag, A., Tachmazidou, I., Deevi, S. V. V., Taiy, H., Smith, K. R., Loesch, D. P., Burren, O. S., et al. (2025) · Nature Genetics · doi:10.1038/s41588-025-02085-6 · Cited by 18

The TALE homeodomain transcription factor MEIS1 activates the pro‐metastatic melanoma cell adhesion molecule Mcam to promote migration of pancreatic cancer cells

von Burstin, J., Bachhuber, F., Paul, M. C., Schmid, R. M., & Rustgi, A. K. (2016) · Molecular Carcinogenesis · doi:10.1002/mc.22547 · Cited by 15

Meis1 Regulates Postnatal Cardiomyocyte Cell Cycle Arrest

Muralidhar, S. A., & Sadek, H. A. (2016) · Springer eBooks · doi:10.1007/978-4-431-54628-3_11 · Cited by 15

Molecular Profiling of Conjunctival Epithelial Side-Population Stem Cells: Atypical Cell Surface Markers and Sources of a Slow-Cycling Phenotype

Akinci, M. A., Turner, H. C., Taveras, M., Barash, A., Wang, Z., Reinach, P. S., & Wolosin, J. M. (2009) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.08-2861 · Cited by 15

Mechanisms and Therapeutic Targets of Cardiac Regeneration: Closing the Age Gap

Castellan, R. F. P., & Meloni, M. (2018) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2018.00007 · Cited by 14

Tumorigenic and Antiproliferative Properties of the TALE-Transcription Factors MEIS2D and MEIS2A in Neuroblastoma

Groß, A., Schulz, C., Kolb, J., Köster, J., Wehner, S., Czaplinski, S., Khilan, A., Rohrer, H., Harter, P. N., Klingebiel, T. E., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-17-1860 · Cited by 13

C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein

Bisaillon, R., Wilhelm, B. T., Krošl, J., & Sauvageau, G. (2011) · Blood · doi:10.1182/blood-2011-05-354076 · Cited by 13

Role of Meis1 in mitochondrial gene transcription of pancreatic cancer cells

Tomoeda, M., Yuki, M., Kubo, C., Yoshizawa, H., Kitamura, M., Nagata, S., Nishizawa, Y., & Tomita, Y. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.06.066 · Cited by 13

Interplay between FLI-1 and the LDB1 complex in murine erythroleukemia cells and during megakaryopoiesis

Giraud, G., Kolovos, P., Boltsis, I., van Staalduinen, J., Guyot, B., Weiss‐Gayet, M., van IJcken, W. F. J., Morlé, F., & Grosveld, F. G. (2021) · iScience · doi:10.1016/j.isci.2021.102210 · Cited by 11

Targeting lysine demethylase 6B ameliorates ASXL1 truncation–mediated myeloid malignancies in preclinical models

Ge, G., Zhang, P., Sui, P., Shi, C., Yang, H., Guo, Y., Rubalcava, I. P., Noor, A., Delma, C. R., Agosto-Peña, J., et al. (2023) · Journal of Clinical Investigation · doi:10.1172/jci163964 · Cited by 10

RLS-associated MEIS transcription factors control distinct processes in human neural stem cells

Kittke, V., Zhao, C., Lam, D. D., Harrer, P., Krężel, W., Schormair, B., Oexle, K., & Winkelmann, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-80266-9 · Cited by 9

A knock-in mouse strain facilitates dynamic tracking and enrichment of MEIS1

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Dental Epithelial Stem Cells Express the Developmental Regulator Meis1

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Delineating MEIS1 cis-regulatory elements active in hematopoietic cells

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Fluorescent genetic barcoding for cellular multiplex analyses

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The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG

Kugler, E., Madiwale, S., Yong, D., Thoms, J. A. I., Birger, Y., Sykes, D. B., Schmoellerl, J., Drakul, A., Priebe, V., Yassin, M., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-41067-2 · Cited by 8

MEIS1-mediated Apoptosis via TNFR1 in Endometriosis

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Association of controlled ovarian hyperstimulation treatment with down-regulation of key regulators involved in embryonic implantation in mice

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Npm1 haploinsufficiency in collaboration with MEIS1 is sufficient to induce AML in mice

Muranyi, A., Ammer, T., Kechter, A., Rawat, V. P. S., Sinha, A., González-Menéndez, I., Quintanilla‐Martínez, L., Azoitei, A., Güneş, Ç., Mupo, A., et al. (2022) · Blood Advances · doi:10.1182/bloodadvances.2022007015 · Cited by 6

Overcoming menin inhibitor resistance in AML cells with combinations including BET proteins and a dual BRG1/BRM inhibitor

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Evaluation of the HOXA9 and MEIS1 genes as a potential biomarker in adult acute myeloid leukemia

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Differential transcriptional control of hematopoiesis in congenital and cyclic neutropenia patients harboring ELANE mutations

Zeidler, A., Borbaran-Bravo, N., Dannenmann, B., Ritter, M. U., Nasri, M., Klimiankou, M., Kandabarau, S., Zahabi, A., König, J., Zeidler, C., et al. (2023) · Haematologica · doi:10.3324/haematol.2023.284033 · Cited by 3

MEIS1: From functional versatility to post-transcriptional/translational regulation

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Lead Optimization and Structure–Activity Relationship Studies on Myeloid Ecotropic Viral Integration Site 1 Inhibitor

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Triple-negative Thrombocythemia and Subsequent Acute Lymphoblastic Leukemia with Additional Somatic Mutations

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Gene Expression Profile Regulated by CREB in K562 Cell Line

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Comparative analysis of 136,401 Admixed Americans and 419,228 Europeans reveals ancestry-specific genetic determinants of clonal haematopoiesisPreprint

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Elucidating the risk factors and oncogene drivers of acute myeloid leukemia

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Chromatin dynamics during hematopoiesis reveal discrete regulatory modules instructing differentiationPreprint

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The role of prolyl hydroxylases in the function of leukaemic stem cells and the development of leukaemia

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Characterization of the putative CALM/AF10 collaborator Meis1 in leukemia development

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Molecular mechanisms of pathogenesis of myeloproliferative neoplasms: deregulation of genes involved in cell proliferation and apoptosis

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Additional file 1 of Evaluation of the HOXA9 and MEIS1 genes as a potential biomarker in adult acute myeloid leukemia

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Sclerotomal hematopoiesis in vertebrate embryos contributes to robustness of the blood system

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Cooperative reading of DECA-CCAAT composite element by the TALE/NF-Y/Sp2 transcription factors

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The role of MEIS inhibitors in cardiac regeneration and protection

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Progress in the role of MEIS1 in MLL-association leukemia

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Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3

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Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus

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Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation

Cai, M., Langer, E. M., Gill, J. G., Satpathy, A. T., Albring, J. C., Wumesh, K. C., Murphy, T. L., & MURPHY, K. M. M. (2012) · Blood · doi:10.1182/blood-2012-01-403139 · Cited by 53

Identification of Meis1 Target Genes Involved in the Induction of AML in Collaboration with NUP98-HOXD13.

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