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Cited by 381

The DOI matches its Crossref record; 150 of the 150 references it cites were found in a registry or an index.

Migratory neighbors and distant invaders: tumor-associated niche cells

Open access
Wels, Jared, Kaplan, Rosandra N., Rafii, Shahin, Lyden, David·2008·Genes & Development

Abstract

The cancer environment is comprised of tumor cells as well as a wide network of stromal and vascular cells participating in the cellular and molecular events necessary for invasion and metastasis. Tumor secretory factors can activate the migration of host cells, both near to and far from the primary tumor site, as well as promote the exodus of cells to distant tissues. Thus, the migration of stromal cells and tumor cells among specialized microenvironments takes place throughout tumor and metastatic progression, providing evidence for the systemic nature of a malignancy. Investigations of the tumor–stromal and stromal–stromal cross-talk involved in cellular migration in cancer may lead to the design of novel therapeutic strategies.

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Crossref · 10.1101/gad.1636908

Cites

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Metadata

Authors
Wels, J., Kaplan, R. N., Rafii, S., & Lyden, D.
Venue
Genes & Development
Published
2008-03-01
Volume
22
Issue
5
Pages
559-574
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W1963759977
Cited by
381
References
150
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: Migratory neighbors and distant invaders: tumor-associated niche cells. https://app.cochat.ai/papers/10.1101/gad.1636908
The paper
Wels, J., Kaplan, R. N., Rafii, S., & Lyden, D. (2008). Migratory neighbors and distant invaders: tumor-associated niche cells. Genes & Development. https://doi.org/10.1101/gad.1636908

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.