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Cited by 342

The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.

Pluripotent stem cell lines

Open access
Yu, Junying, Thomson, James A.·2008·Genes & Development

Abstract

The derivation of human embryonic stem cells 10 years ago ignited an explosion of public interest in stem cells, yet this achievement depended on prior decades of research on mouse embryonic carcinoma cells and embryonic stem cells. In turn, the recent derivation of mouse and human induced pluripotent stem cells depended on the prior studies on mouse and human embryonic stem cells. Both human embryonic stem cells and induced pluripotent stem cells can self-renew indefinitely in vitro while maintaining the ability to differentiate into advanced derivatives of all three germ layers, features very useful for understanding the differentiation and function of human tissues, for drug screen and toxicity testing, and for cellular transplantation therapies. Here we review the family of pluripotent cell lines derived from early embryos and from germ cells, and compare them with the more recently described induced pluripotent stem cells.

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Metadata

Authors
Yu, J., & Thomson, J. A.
Venue
Genes & Development
Published
2008-08-01
Volume
22
Issue
15
Pages
1987-1997
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W2019209906
Cited by
342
References
125
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: Pluripotent stem cell lines. https://app.cochat.ai/papers/10.1101/gad.1689808
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Yu, J., & Thomson, J. A. (2008). Pluripotent stem cell lines. Genes & Development. https://doi.org/10.1101/gad.1689808

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.