The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula
Open accessAbstract
In the model legume Medicago truncatula, we identified a new transcription factor of the CCAAT-binding family, MtHAP2-1, for which RNA interference (RNAi) and in situ hybridization experiments indicate a key role during nodule development, possibly by controlling nodule meristem function. We could also show that MtHAP2-1 is regulated by microRNA169, whose overexpression leads to the same nodule developmental block as MtHAP2-1 RNAi constructs. The complementary expression pattern of miR169 and MtHAP2-1 and the phenotype of miR169-resistant MtHAP2-1 nodules strongly suggest, in addition, that the miR169-mediated restriction of MtHAP2-1 expression to the nodule meristematic zone is essential for the differentiation of nodule cells.
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Cites
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Cited by
How rhizobial symbionts invade plants: the Sinorhizobium–Medicago model
Jones, K. M., Kobayashi, H., Davies, B. W., Taga, M. E., & Walker, G. C. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1705 · Cited by 937
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Roles of Plant Small RNAs in Biotic Stress Responses
Ruiz-Ferrer, V., & Voinnet, O. (2009) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.043008.092111 · Cited by 623
Vaucheret, H. (2008) · Trends in Plant Science · doi:10.1016/j.tplants.2008.04.007 · Cited by 585
Deep sequencing of tomato short RNAs identifies microRNAs targeting genes involved in fruit ripening
Moxon, S., Jing, R., Szittya, G., Schwach, F., Rusholme Pilcher, R. L., Moulton, V., & Dalmay, T. (2008) · Genome Research · doi:10.1101/gr.080127.108 · Cited by 470
Metadata
- Authors
- Combier, J.-P., Frugier, F., de Billy, F., Boualem, A., El-Yahyaoui, F., Moreau, S., Vernié, T., Ott, T., Gamas, P., Crespi, M., & Niebel, A.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2006-11-15
- Volume
- 20
- Issue
- 22
- Pages
- 3084-3088
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2095594212
- Cited by
- 517
- References
- 22
- Type
- posted content
- Language
- en
- Open access
- diamond
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- CoChat. (2026). Citation check: MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula. https://app.cochat.ai/papers/10.1101/gad.402806
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- Combier, J.-P., Frugier, F., de Billy, F., Boualem, A., El-Yahyaoui, F., Moreau, S., Vernié, T., Ott, T., Gamas, P., Crespi, M., & Niebel, A. (2006). MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula. Genes & Development. https://doi.org/10.1101/gad.402806
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