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Cited by 566

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

twist and snail as positive and negative regulators during Drosophila mesoderm development.

Open access
Leptin, M·1991·Genes & Development

Abstract

twist and snail are members of the helix-loop-helix and zinc-finger protein families, respectively, and determine the development of the mesoderm in Drosophila. This paper analyzes their role in mesoderm development by examining how they affect the expression of downstream genes. twist and snail act by regulating gene expression in the mesoderm and in neighboring regions, and have distinct roles in this process. snail prevents expression in the mesoderm of genes that are destined to be active only in more lateral or dorsal regions. twist is required for the activation of downstream mesodermal genes. twist is also required for the full expression of snail and for the maintenance of its own expression. Only the absence of both twist and snail results in the complete loss of all mesodermal characteristics.

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Metadata

Authors
Leptin, M.
Venue
Genes & Development
Published
1991-09
Volume
5
Issue
9
Pages
1568-1576
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W2064387879
Cited by
566
References
32
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: twist and snail as positive and negative regulators during Drosophila mesoderm development. https://app.cochat.ai/papers/10.1101/gad.5.9.1568
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Leptin, M. (1991). twist and snail as positive and negative regulators during Drosophila mesoderm development. Genes & Development. https://doi.org/10.1101/gad.5.9.1568

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.